Protein: ITB3
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)

Gene: ITB3, Itgb3
Organism: Mus musculus
Interactions: 117
UniProt ID: O54890

Gene Ontology (top 5):
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0001968 - fibronectin binding
GO:0002020 - protease binding
GO:0002687 - positive regulation of leukocyte migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

222489

ITB3
Integrin beta-3

1

14

High-throughput

0.647

High

222550

FLNB
Filamin-B

1

20

High-throughput

0.647

High

222557

FLNA
Filamin-A

1

20

High-throughput

0.647

High

222496

ITA5
Integrin alpha-5

1

20

Small-scale

0.618

High

222493

SRC
Proto-oncogene tyrosine-protein kinase Src

2

11

Small-scale

0.584

High

222569

FLNC
Filamin-C

1

20

High-throughput

0.579

High

222508

ITAV
Integrin alpha-V

1

20

Small-scale

0.575

High

222509

PA24A
Cytosolic phospholipase A2

1

4

Small-scale

0.515

High

222513

KPCB
Protein kinase C beta type

1

14

Small-scale

0.515

High

57453

UBR4
E3 ubiquitin-protein ligase UBR4

1

2

High-throughput

0.501

High

57477

A2ANY6
Midasin

1

11

High-throughput

0.501

High

93811

E9QLK7
Transformation/transcription domain-associated protein

1

3

High-throughput

0.501

High

101831

F8WIE5
E3 ubiquitin-protein ligase

1

10

High-throughput

0.501

High

102703

G3X9H5
Huntingtin

1

3

High-throughput

0.501

High

139937

DIAP1
Protein diaphanous homolog 1

1

3

High-throughput

0.501

High

140345

MA2B1
Lysosomal alpha-mannosidase

1

6

High-throughput

0.501

High

222490

SPT5H
Transcription elongation factor SPT5

1

3

High-throughput

0.501

High

222491

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

1

High-throughput

0.501

High

222492

BIRC6
Baculoviral IAP repeat-containing protein 6

1

2

High-throughput

0.501

High

222494

ENPL
Endoplasmin

1

1

High-throughput

0.501

High

222495

NUCL
Nucleolin

1

2

High-throughput

0.501

High

222497

MAP1B
Microtubule-associated protein 1B

1

6

High-throughput

0.501

High

222501

CBL
E3 ubiquitin-protein ligase CBL

1

4

High-throughput

0.501

High

222502

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

High-throughput

0.501

High

222503

MOV10
Putative helicase MOV-10

1

8

High-throughput

0.501

High

222504

TLN1
Talin-1

1

20

High-throughput

0.501

High

222505

UBA1Y
Ubiquitin-like modifier-activating enzyme 1 Y

1

3

High-throughput

0.501

High

222506

DYN2
Dynamin-2

1

1

High-throughput

0.501

High

222511

HS74L
Heat shock 70 kDa protein 4L

1

4

High-throughput

0.501

High

222512

MCM4
DNA replication licensing factor MCM4

1

5

High-throughput

0.501

High

222514

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.501

High

222515

TP53B
TP53-binding protein 1

1

8

High-throughput

0.501

High

222516

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.501

High

222517

MCM6
DNA replication licensing factor MCM6

1

5

High-throughput

0.501

High

222518

PRKDC
DNA-dependent protein kinase catalytic subunit

1

3

High-throughput

0.501

High

222520

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

3

High-throughput

0.501

High

222521

IF2P
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.501

High

222522

PSA
Puromycin-sensitive aminopeptidase

1

2

High-throughput

0.501

High

222523

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.501

High

222524

Q3U2G2
Heat shock 70 kDa protein 4

1

3

High-throughput

0.501

High

222527

PUR4
Phosphoribosylformylglycinamidine synthase

1

1

High-throughput

0.501

High

222529

HCFC1
Host cell factor 1

1

2

High-throughput

0.501

High

222530

EWS
RNA-binding protein EWS

1

4

High-throughput

0.501

High

222531

HS105
Heat shock protein 105 kDa

1

4

High-throughput

0.501

High

222533

MYH10
Myosin-10

1

4

High-throughput

0.501

High

222535

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

19

High-throughput

0.501

High

222537

VINC
Vinculin

1

15

High-throughput

0.501

High

222539

MYOF
Myoferlin

1

5

High-throughput

0.501

High

222540

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.501

High

222542

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

1

High-throughput

0.501

High

222544

XPO1
Exportin-1

1

3

High-throughput

0.501

High

222545

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.501

High

222546

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

8

High-throughput

0.501

High

222548

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

3

High-throughput

0.501

High

222553

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.501

High

222555

IPO5
Importin-5

1

1

High-throughput

0.501

High

222556

SRRM2
Serine/arginine repetitive matrix protein 2

1

6

High-throughput

0.501

High

222558

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.501

High

222561

SMC2
Structural maintenance of chromosomes protein 2

1

6

High-throughput

0.501

High

222563

IPO11
Importin-11

1

9

High-throughput

0.501

High

222564

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.501

High

222566

MYH9
Myosin-9

1

4

High-throughput

0.501

High

222567

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.501

High

222568

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.501

High

222571

SFPQ
Splicing factor, proline- and glutamine-rich

1

2

High-throughput

0.501

High

222572

MA2C1
Alpha-mannosidase 2C1

1

6

High-throughput

0.501

High

222576

OGFR
Opioid growth factor receptor

1

2

High-throughput

0.501

High

222577

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.501

High

222579

IPO7
Importin-7

1

6

High-throughput

0.501

High

222580

RENT1
Regulator of nonsense transcripts 1

1

8

High-throughput

0.501

High

222581

XPO2
Exportin-2

1

8

High-throughput

0.501

High

222584

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.501

High

222586

PLEC
Plectin

1

13

High-throughput

0.501

High

222587

UBQL2
Ubiquilin-2

1

2

Small-scale

0.501

High

222588

VAV3
Guanine nucleotide exchange factor VAV3

1

2

High-throughput

0.501

High

222589

PDC6I
Programmed cell death 6-interacting protein

1

4

High-throughput

0.501

High

222592

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.501

High

222528

CAPR1
Caprin-1

1

0

High-throughput

0.480

High

222538

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.480

High

222549

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.480

High

222570

OAS3
2'-5'-oligoadenylate synthase 3

1

0

High-throughput

0.480

High

222578

DNSL2
Deoxyribonuclease-1-like 2

1

0

High-throughput

0.480

High

222499

KPCA
Protein kinase C alpha type

1

14

Small-scale

0.479

High

222500

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

1

High-throughput

0.479

High

222507

CSK
Tyrosine-protein kinase CSK

1

12

Small-scale

0.479

High

222510

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.479

High

222519

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.479

High

82743

B9EKJ1
Spna2 protein

1

19

High-throughput

0.457

High

93795

E9QKZ2
Importin 9

1

8

High-throughput

0.457

High

100193

TPR
Nucleoprotein TPR

1

9

High-throughput

0.457

High

193230

AP1B1
AP-1 complex subunit beta-1

1

3

High-throughput

0.457

High

222498

AP2A2
AP-2 complex subunit alpha-2

1

1

High-throughput

0.457

High

222525

SC24A
Protein transport protein Sec24A

1

1

High-throughput

0.457

High

222526

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.457

High

222532

KINH
Kinesin-1 heavy chain

1

1

High-throughput

0.457

High

222536

IF4G2
Eukaryotic translation initiation factor 4 gamma 2

1

5

High-throughput

0.457

High

222541

NOMO1
BOS complex subunit NOMO1

1

2

High-throughput

0.457

High

222543

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

2

High-throughput

0.457

High

222547

ATX2L
Ataxin-2-like protein

1

4

High-throughput

0.457

High

222551

Q80X98
RNA helicase

1

1

High-throughput

0.457

High

222552

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.457

High

222554

Q8BIX2
GCN1 activator of EIF2AK4

1

7

High-throughput

0.457

High

222562

COPA
Coatomer subunit alpha

1

1

High-throughput

0.457

High

222565

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.457

High

222574

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

High-throughput

0.457

High

222575

PECR
Peroxisomal trans-2-enoyl-CoA reductase

1

2

High-throughput

0.457

High

222582

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

7

High-throughput

0.457

High

222583

COPB
Coatomer subunit beta

1

2

High-throughput

0.457

High

222585

SON
Protein SON

1

10

High-throughput

0.457

High

222590

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

2

High-throughput

0.457

High

222591

SYVC
Valine--tRNA ligase

1

5

High-throughput

0.457

High

222534

KPCD1
Serine/threonine-protein kinase D1

1

13

Small-scale

0.445

High

93238

E9PWG6
Non-SMC condensin I complex, subunit G

1

0

High-throughput

0.261

Low

222559

Q8C1W8
proton-translocating NAD(P)(+) transhydrogenase

1

0

High-throughput

0.261

Low

222560

Q8C839
Splicing factor 3B subunit 1

1

0

High-throughput

0.261

Low

222573

Q921K2
Poly [ADP-ribose] polymerase

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024