HitPredict

Interactor 1: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	25416956, 32296183, 36574265, 31515488, unassigned1304
Identification Methods	two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 117
+	Hs
		891151 TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306178 TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1064108 TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1064148 TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1064123 TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		1326219 SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		891236 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		1255687 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Hs
		306245 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Ce
		361126 MYO1_CAEEL (27-547): 1.23e-10: 67: 13.88		LGG1_CAEEL (1-116): 3.74e-55: 169: 78.45
+	Hs
		725011 MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33		GBRL1_HUMAN (1-117): 4.54e-56: 171: 100.00
+	Ce
		522318 MYO2_CAEEL (148-525): 6.16e-09: 61.5: 16.22		LGG1_CAEEL (1-116): 3.74e-55: 169: 78.45
+	Hs
		1255678 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1255690 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1255684 RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Hs
		502871 LAMC1_HUMAN (4-285): 9.73e-10: 64.2: 9.27		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62