HitPredict

Interactor 1: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28515276, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0016607 - nuclear speck
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 972 Hs			1 551
+	Hs
		846975 U5S1_HUMAN (1-972): 0: 1062: 100.00		SMCA4_HUMAN (126-551): 8.83e-45: 172: 15.98
+	Hs
		1031337 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP4_HUMAN (81-517): 7.23e-31: 129: 13.51
+	Hs
		516526 U5S1_HUMAN (1-972): 0: 1062: 100.00		PABP1_HUMAN (81-518): 2.46e-24: 109: 16.40
+	Hs
		867098 U5S1_HUMAN (1-972): 0: 1062: 100.00		SC24C_HUMAN (233-440): 1.79e-12: 72.2: 17.05
+	Hs
		1064661 U5S1_HUMAN (1-972): 0: 1062: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Sp
		292934 SN114_SCHPO (1-970): 0: 928: 54.22		PABP_SCHPO (60-372): 7.58e-19: 92.3: 14.20