HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 33961781, 9952408, 21763699
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, blue native page
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~PDZ, PDZ~PDZ, PDZ~PID, PDZ~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 926
Hs

1 837
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+ Rn
+ Ce
+ Dm
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+ Dm

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Last updated: 15 Jul 2024