Interactor 1: PTEN (G5EE01)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Abnormal dauer formation protein 18)
Gene: daf-18

Interactor 2: INSR (Q968Y9)
Insulin-like receptor (IR) (EC 2.7.10.1) (Abnormal dauer formation protein 2) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta]
Gene: daf-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 23995781
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms GO:0005886 - plasma membrane
GO:0006606 - protein import into nucleus
GO:0008340 - determination of adult lifespan
GO:0030424 - axon
GO:0040024 - dauer larval development
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 962
Ce

1 1846
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Last updated: 15 Jul 2024