Protein: DNJC3
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)

Gene: DNJC3, DNAJC3
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q13217

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

535009

BIP
Endoplasmic reticulum chaperone BiP

3

20

Small-scale

0.839

High

624047

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

2

14

Small-scale

0.793

High

1098494

DNJB9
DnaJ homolog subfamily B member 9

2

19

High-throughput

0.776

High

1098495

DJB11
DnaJ homolog subfamily B member 11

2

20

High-throughput

0.759

High

566656

PDIA4
Protein disulfide-isomerase A4

2

20

High-throughput

0.754

High

1098491

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

20

Small-scale

0.724

High

1098428

ERN2
Serine/threonine-protein kinase/endoribonuclease IRE2

1

6

High-throughput

0.691

High

185654

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

19

High-throughput

0.647

High

258859

DNJA2
DnaJ homolog subfamily A member 2

1

20

High-throughput

0.618

High

274559

DNJB6
DnaJ homolog subfamily B member 6

1

20

High-throughput

0.618

High

298903

DNJB5
DnaJ homolog subfamily B member 5

1

20

High-throughput

0.618

High

452248

PDIA1
Protein disulfide-isomerase

1

20

High-throughput

0.618

High

537091

HSP7C
Heat shock cognate 71 kDa protein

1

20

Small-scale

0.618

High

573457

ENPL
Endoplasmin

1

20

High-throughput

0.618

High

656111

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

6

High-throughput

0.618

High

717462

PDIA3
Protein disulfide-isomerase A3

1

20

High-throughput

0.618

High

761382

HS71L
Heat shock 70 kDa protein 1-like

1

20

High-throughput

0.618

High

761661

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.618

High

1098395

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

20

High-throughput

0.618

High

1098399

PDIA6
Protein disulfide-isomerase A6

1

20

High-throughput

0.618

High

1098426

TMTC3
Protein O-mannosyl-transferase TMTC3

1

20

High-throughput

0.618

High

1098437

DJC10
DnaJ homolog subfamily C member 10

1

20

High-throughput

0.618

High

1098445

TXND5
Thioredoxin domain-containing protein 5

1

20

High-throughput

0.618

High

1098452

DNJA4
DnaJ homolog subfamily A member 4

1

20

High-throughput

0.618

High

1098460

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

18

High-throughput

0.618

High

1098465

DNJC1
DnaJ homolog subfamily C member 1

1

20

High-throughput

0.618

High

1098470

DNJC7
DnaJ homolog subfamily C member 7

1

19

High-throughput

0.618

High

1098478

TMX1
Thioredoxin-related transmembrane protein 1

1

20

High-throughput

0.618

High

1098487

DJB12
DnaJ homolog subfamily B member 12

1

18

High-throughput

0.618

High

1098497

SEC63
Translocation protein SEC63 homolog

1

18

High-throughput

0.618

High

1098507

HYOU1
Hypoxia up-regulated protein 1

1

20

High-throughput

0.618

High

1098405

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

9

High-throughput

0.611

High

1098493

TEN3
Teneurin-3

2

5

High-throughput

0.601

High

215815

P52K
52 kDa repressor of the inhibitor of the protein kinase

2

8

Small-scale

0.594

High

229704

CALU
Calumenin

2

18

High-throughput

0.584

High

241572

PRKN
E3 ubiquitin-protein ligase parkin

2

13

High-throughput

0.584

High

951132

SC61B
Protein transport protein Sec61 subunit beta

2

4

High-throughput

0.584

High

289081

DEDD
Death effector domain-containing protein

2

0

High-throughput

0.576

High

1047533

NOTC2
Neurogenic locus notch homolog protein 2

1

1

High-throughput

0.575

High

1098467

CNT3B
Contactin-associated protein-like 3B

1

9

High-throughput

0.575

High

1098471

EGFL8
Epidermal growth factor-like protein 8

1

8

High-throughput

0.575

High

467827

BGLR
Beta-glucuronidase

2

2

High-throughput

0.571

High

540433

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.571

High

1098393

MOGS
Mannosyl-oligosaccharide glucosidase

2

1

High-throughput

0.571

High

1098477

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

2

5

High-throughput

0.571

High

1098489

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

2

9

High-throughput

0.571

High

1098444

TTC13
Tetratricopeptide repeat protein 13

1

20

High-throughput

0.553

High

1098504

DJC16
DnaJ homolog subfamily C member 16

1

20

High-throughput

0.553

High

341300

ECEL1
Endothelin-converting enzyme-like 1

2

6

High-throughput

0.549

High

1098416

OLM2B
Olfactomedin-like protein 2B

2

2

High-throughput

0.549

High

143735

WN10B
Protein Wnt-10b

1

4

High-throughput

0.536

High

144093

WNT7A
Protein Wnt-7a

1

4

High-throughput

0.536

High

251151

B4GT4
Beta-1,4-galactosyltransferase 4

1

1

High-throughput

0.536

High

289316

FCN3
Ficolin-3

1

2

High-throughput

0.536

High

472053

MET
Hepatocyte growth factor receptor

1

18

High-throughput

0.536

High

548009

PSPC
Surfactant protein C

1

2

High-throughput

0.536

High

582328

ARSA
Arylsulfatase A

1

5

High-throughput

0.536

High

647349

IDS
Iduronate 2-sulfatase

1

5

High-throughput

0.536

High

935727

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.536

High

942149

WNT3A
Protein Wnt-3a

1

4

High-throughput

0.536

High

1009142

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

8

High-throughput

0.536

High

1013290

HTRA4
Serine protease HTRA4

1

2

High-throughput

0.536

High

1098421

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.536

High

1098436

GLBL2
Beta-galactosidase-1-like protein 2

1

5

High-throughput

0.536

High

1098454

AGRV1
Adhesion G-protein coupled receptor V1

1

5

High-throughput

0.536

High

1098457

GGH
Gamma-glutamyl hydrolase

1

3

High-throughput

0.536

High

1098475

WN10A
Protein Wnt-10a

1

4

High-throughput

0.536

High

1098499

TSP50
Probable threonine protease PRSS50

1

13

High-throughput

0.536

High

1098509

PCDB3
Protocadherin beta-3

1

9

High-throughput

0.536

High

1098473

STK31
Serine/threonine-protein kinase 31

1

0

High-throughput

0.517

High

169247

CASQ2
Calsequestrin-2

1

20

High-throughput

0.515

High

680699

CATS
Cathepsin S

1

5

High-throughput

0.515

High

692950

DPP4
Dipeptidyl peptidase 4

1

6

High-throughput

0.515

High

1098410

FBLN7
Fibulin-7

1

6

High-throughput

0.514

High

539600

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.513

High

627902

TCO2
Transcobalamin-2

1

0

High-throughput

0.513

High

772386

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.513

High

1067006

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.513

High

1098474

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

1098481

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.513

High

507913

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

14

High-throughput

0.501

High

439720

INSR
Insulin receptor

1

20

High-throughput

0.500

High

465504

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.500

High

477233

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

20

High-throughput

0.500

High

1098403

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.500

High

1098406

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.500

High

1098414

EPHAA
Ephrin type-A receptor 10

1

14

High-throughput

0.500

High

1098502

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.500

High

1098409

RABL6
Rab-like protein 6

1

0

High-throughput

0.493

High

64351

CDHR4
Cadherin-related family member 4

1

11

High-throughput

0.489

High

841542

I12R1
Interleukin-12 receptor subunit beta-1

1

4

High-throughput

0.489

High

1098402

EPHA7
Ephrin type-A receptor 7

1

13

High-throughput

0.489

High

1098508

PCDB7
Protocadherin beta-7

1

9

High-throughput

0.489

High

63136

CL18A
C-type lectin domain family 18 member A

1

6

High-throughput

0.479

High

137059

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

14

High-throughput

0.479

High

160705

TOR1A
Torsin-1A

1

7

High-throughput

0.479

High

218139

TGON2
Trans-Golgi network integral membrane protein 2

1

12

High-throughput

0.479

High

251887

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

14

High-throughput

0.479

High

293645

CD123
Translation initiation factor eIF2 assembly protein

1

10

High-throughput

0.479

High

360187

GSHR
Glutathione reductase, mitochondrial

1

5

High-throughput

0.479

High

363217

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

377562

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

2

High-throughput

0.479

High

408044

TBB4A
Tubulin beta-4A chain

1

19

High-throughput

0.479

High

417408

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

535836

LAMC1
Laminin subunit gamma-1

1

11

High-throughput

0.479

High

541465

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

552571

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

4

High-throughput

0.479

High

566973

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

7

High-throughput

0.479

High

571424

GLU2B
Glucosidase 2 subunit beta

1

3

High-throughput

0.479

High

580624

AMPN
Aminopeptidase N

1

8

High-throughput

0.479

High

650733

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

12

High-throughput

0.479

High

666093

PPAC
Low molecular weight phosphotyrosine protein phosphatase

1

2

High-throughput

0.479

High

697870

CALR
Calreticulin

1

20

High-throughput

0.479

High

698623

CALX
Calnexin

1

20

High-throughput

0.479

High

716178

ERP29
Endoplasmic reticulum resident protein 29

1

20

High-throughput

0.479

High

720468

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

3

High-throughput

0.479

High

813074

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

4

High-throughput

0.479

High

820633

CEAM6
Cell adhesion molecule CEACAM6

1

9

High-throughput

0.479

High

880534

LMAN1
Protein ERGIC-53

1

7

High-throughput

0.479

High

903897

BAP31
B-cell receptor-associated protein 31

1

5

High-throughput

0.479

High

947179

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

7

High-throughput

0.479

High

998276

H31
Histone H3.1

1

4

High-throughput

0.479

High

1009828

NUCB2
Nucleobindin-2

1

3

High-throughput

0.479

High

1038851

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

14

High-throughput

0.479

High

1041508

KMT2A
Histone-lysine N-methyltransferase 2A

1

9

High-throughput

0.479

High

1058398

CKAP4
Cytoskeleton-associated protein 4

1

13

High-throughput

0.479

High

1093504

TRDN
Triadin

1

10

High-throughput

0.479

High

1096949

PRDX4
Peroxiredoxin-4

1

4

High-throughput

0.479

High

1098391

SMAD4
Mothers against decapentaplegic homolog 4

1

6

High-throughput

0.479

High

1098396

GANAB
Neutral alpha-glucosidase AB

1

5

High-throughput

0.479

High

1098398

EMC2
ER membrane protein complex subunit 2

1

15

High-throughput

0.479

High

1098401

RCN1
Reticulocalbin-1

1

18

High-throughput

0.479

High

1098407

TECT1
Tectonic-1

1

7

High-throughput

0.479

High

1098408

P3H1
Prolyl 3-hydroxylase 1

1

7

High-throughput

0.479

High

1098412

TGO1
Transport and Golgi organization protein 1 homolog

1

7

High-throughput

0.479

High

1098419

ERAP2
Endoplasmic reticulum aminopeptidase 2

1

8

High-throughput

0.479

High

1098424

SYNE3
Nesprin-3

1

6

High-throughput

0.479

High

1098425

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1098427

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

3

High-throughput

0.479

High

1098429

PLGT3
Protein O-glucosyltransferase 3

1

2

High-throughput

0.479

High

1098430

CNTRL
Centriolin

1

3

High-throughput

0.479

High

1098433

KTN1
Kinectin

1

4

High-throughput

0.479

High

1098434

PLD3
5'-3' exonuclease PLD3

1

8

High-throughput

0.479

High

1098440

EMC1
ER membrane protein complex subunit 1

1

4

High-throughput

0.479

High

1098443

GT251
Procollagen galactosyltransferase 1

1

14

High-throughput

0.479

High

1098449

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

4

High-throughput

0.479

High

1098450

PO210
Nuclear pore membrane glycoprotein 210

1

5

High-throughput

0.479

High

1098455

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

6

High-throughput

0.479

High

1098456

AKAP1
A-kinase anchor protein 1, mitochondrial

1

8

High-throughput

0.479

High

1098459

LRC59
Leucine-rich repeat-containing protein 59

1

11

High-throughput

0.479

High

1098461

PLD4
5'-3' exonuclease PLD4

1

8

High-throughput

0.479

High

1098462

ASTRA
Protein Aster-A

1

4

High-throughput

0.479

High

1098463

ERO1A
ERO1-like protein alpha

1

3

High-throughput

0.479

High

1098466

CALR3
Calreticulin-3

1

20

High-throughput

0.479

High

1098468

CLCC1
Chloride channel CLIC-like protein 1

1

3

High-throughput

0.479

High

1098469

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.479

High

1098472

CNPY3
Protein canopy homolog 3

1

1

Small-scale

0.479

High

1098476

ADT4
ADP/ATP translocase 4

1

5

High-throughput

0.479

High

1098479

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.479

High

1098482

ZFYV1
Zinc finger FYVE domain-containing protein 1

1

4

Small-scale

0.479

High

1098483

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.479

High

1098484

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

1

High-throughput

0.479

High

1098490

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

8

High-throughput

0.479

High

1098492

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.479

High

1098496

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1098500

GRID1
Glutamate receptor ionotropic, delta-1

1

2

High-throughput

0.479

High

1098501

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.479

High

1098503

CNPY2
Protein canopy homolog 2

1

1

High-throughput

0.479

High

771768

SCN4A
Sodium channel protein type 4 subunit alpha

1

1

High-throughput

0.470

High

946654

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

Small-scale

0.458

High

1098394

MLEC
Malectin

1

0

High-throughput

0.458

High

1098400

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.458

High

1098448

ABCF1
ATP-binding cassette sub-family F member 1

1

0

High-throughput

0.458

High

1055044

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.457

High

73800

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

4

High-throughput

0.445

High

167445

WNT9A
Protein Wnt-9a

1

4

High-throughput

0.445

High

183393

MATN3
Matrilin-3

1

2

Small-scale

0.445

High

295737

AP1G2
AP-1 complex subunit gamma-like 2

1

4

High-throughput

0.445

High

388624

C1QA
Complement C1q subcomponent subunit A

1

4

High-throughput

0.445

High

505824

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

4

High-throughput

0.445

High

519607

LYAG
Lysosomal alpha-glucosidase

1

5

High-throughput

0.445

High

593660

BGAL
Beta-galactosidase

1

5

High-throughput

0.445

High

617294

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

2

High-throughput

0.445

High

851114

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

5

High-throughput

0.445

High

937389

LAMB2
Laminin subunit beta-2

1

10

High-throughput

0.445

High

946235

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

2

High-throughput

0.445

High

976803

LCN6
Epididymal-specific lipocalin-6

1

2

High-throughput

0.445

High

1006191

CNTP1
Contactin-associated protein 1

1

8

High-throughput

0.445

High

1060347

SLC31
Amino acid transporter heavy chain SLC3A1

1

3

High-throughput

0.445

High

1098397

MBTP1
Membrane-bound transcription factor site-1 protease

1

6

High-throughput

0.445

High

1098404

EXT1
Exostosin-1

1

2

High-throughput

0.445

High

1098415

GT253
Inactive glycosyltransferase 25 family member 3

1

14

High-throughput

0.445

High

1098417

TEN4
Teneurin-4

1

5

High-throughput

0.445

High

1098431

GALT7
N-acetylgalactosaminyltransferase 7

1

3

High-throughput

0.445

High

1098438

AGRG5
Adhesion G-protein coupled receptor G5

1

3

High-throughput

0.445

High

1098439

LYPD1
Ly6/PLAUR domain-containing protein 1

1

1

High-throughput

0.445

High

1098442

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.445

High

1098451

ARB2A
Cotranscriptional regulator ARB2A

1

1

High-throughput

0.445

High

1098464

LOXL4
Lysyl oxidase homolog 4

1

5

High-throughput

0.445

High

1098485

TEN2
Teneurin-2

1

4

High-throughput

0.445

High

1098506

TMED5
Transmembrane emp24 domain-containing protein 5

1

3

High-throughput

0.445

High

1098510

PCDBB
Protocadherin beta-11

1

9

High-throughput

0.445

High

105860

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

521669

H14
Histone H1.4

1

1

High-throughput

0.437

High

1098390

TIF1B
Transcription intermediary factor 1-beta

1

7

High-throughput

0.437

High

1098411

NOMO2
BOS complex subunit NOMO2

1

3

High-throughput

0.437

High

1098413

TOIP1
Torsin-1A-interacting protein 1

1

3

High-throughput

0.437

High

1098418

TECT3
Tectonic-3

1

7

High-throughput

0.437

High

1098423

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

1098480

TM231
Transmembrane protein 231

1

3

High-throughput

0.437

High

1098486

T106B
Transmembrane protein 106B

1

7

High-throughput

0.437

High

1098488

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

3

High-throughput

0.437

High

1098505

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

327048

NXPH3
Neurexophilin-3

1

0

High-throughput

0.426

High

501818

CO4A
Complement C4-A

1

0

High-throughput

0.426

High

1098420

FBX38
F-box only protein 38

1

0

High-throughput

0.426

High

1098453

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.426

High

332213

UCP5
Brain mitochondrial carrier protein 1

1

9

High-throughput

0.407

High

907899

PLXA3
Plexin-A3

1

6

High-throughput

0.407

High

1098392

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

2

High-throughput

0.407

High

1098432

ZN546
Zinc finger protein 546

1

4

High-throughput

0.407

High

1098441

ZN283
Zinc finger protein 283

1

5

High-throughput

0.407

High

1098446

MOT11
Monocarboxylate transporter 11

1

9

High-throughput

0.407

High

1098447

DIK2A
Divergent protein kinase domain 2A

1

1

High-throughput

0.407

High

1098458

T106A
Transmembrane protein 106A

1

7

High-throughput

0.407

High

1098498

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

3

High-throughput

0.407

High

51322

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

399441

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.232

Low

1098422

MOXD1
DBH-like monooxygenase protein 1

1

0

High-throughput

0.232

Low

1098435

SPA12
Serpin A12

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025