HitPredict

Interactor 1: APRIO (F7VJQ1)
Alternative prion protein (AltPrP)
Gene: PRNP

Interactor 2: PLCB1 (Q9NQ66)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-I) (PLC-I) (Phospholipase C-beta-1) (PLC-beta-1)
Gene: PLCB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29791485, 33618749
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 73 Hs			1 1216
+	Hs
		106863 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLCL2_HUMAN (18-1017): 0: 836: 26.39
+	Hs
		105966 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLCL1_HUMAN (18-1066): 0: 788: 24.95
+	Hs
		105597 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLCD1_HUMAN (8-796): 0: 767: 28.34
+	Hs
		105301 APRIO_HUMAN (1-73): 1.71e-29: 100: 100.00		PLCG1_HUMAN (491-792): 3.23e-77: 281: 31.29