HitPredict

Interactor 1: P2RY6 (Q15077)
P2Y purinoceptor 6 (P2Y6)
Gene: P2RY6

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 328 Hs			1 2671
+	Hs
		91007 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		E1NZA1_HUMAN (1-2671): 0: 2131: 99.96
+	Hs
		723080 OPRM_HUMAN (4-316): 2.42e-65: 212: 23.81		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		824729 NPY2R_HUMAN (11-318): 2.07e-61: 202: 20.25		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		1067562 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		TNPO1_HUMAN (908-1705): 1.2e-50: 198: 13.59
+	Hs
		127275 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		672424 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		2AAB_HUMAN (2265-2670): 2.67e-36: 149: 14.67
+	Hs
		787488 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		787471 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		787434 CXCR4_HUMAN (4-321): 1.82e-67: 216: 25.94		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		723279 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		787417 NPY2R_HUMAN (11-318): 2.07e-61: 202: 20.25		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		1067530 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		723340 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		1067517 P2RY6_HUMAN (1-328): 2.13e-71: 226: 100.00		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		1030954 GPR17_HUMAN (9-317): 1.22e-68: 220: 29.13		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		723051 OPRM_HUMAN (4-316): 2.42e-65: 212: 23.81		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		723321 APJ_HUMAN (28-323): 1.65e-65: 212: 25.99		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		429069 ADRB2_HUMAN (29-323): 1.45e-64: 211: 17.96		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		686654 CCR1_HUMAN (9-319): 6.8e-63: 205: 24.04		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Hs
		824710 NPY2R_HUMAN (11-318): 2.07e-61: 202: 20.25		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24