Protein: AP2B
Transcription factor AP-2-beta (AP2-beta) (Activating enhancer-binding protein 2-beta)

Gene: AP2B, TFAP2B
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q92481

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431591

AP2A
Transcription factor AP-2-alpha

2

9

Small-scale

0.789

High

1280266

AP2D
Transcription factor AP-2-delta

1

9

High-throughput

0.691

High

1363182

CITE2
Cbp/p300-interacting transactivator 2

2

4

Small-scale

0.595

High

340374

YETS4
YEATS domain-containing protein 4

1

0

Small-scale

0.549

High

1363183

SSBP4
Single-stranded DNA-binding protein 4

1

3

High-throughput

0.541

High

1363187

KLH20
Kelch-like protein 20

1

2

High-throughput

0.536

High

1139781

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.515

High

1347338

LMO3
LIM domain only protein 3

1

1

High-throughput

0.515

High

1363184

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.513

High

993678

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.508

High

170255

AURKA
Aurora kinase A

1

2

Small-scale

0.501

High

1363180

CITE4
Cbp/p300-interacting transactivator 4

1

7

Small-scale

0.501

High

1363181

CITE1
Cbp/p300-interacting transactivator 1

1

7

Small-scale

0.501

High

1363186

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

1

High-throughput

0.501

High

1328748

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

2

High-throughput

0.494

High

966685

1433G
14-3-3 protein gamma

1

0

High-throughput

0.493

High

1363177

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

406441

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.479

High

414310

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

1258856

KCTD1
BTB/POZ domain-containing protein KCTD1

1

5

Small-scale

0.479

High

1363175

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1363176

CBP
CREB-binding protein

1

2

Small-scale

0.479

High

1363178

H2A1C
Histone H2A type 1-C

1

0

High-throughput

0.438

High

1363179

MEG10
Multiple epidermal growth factor-like domains protein 10

1

5

Small-scale

0.437

High

690525

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.279

Low

1363185

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025