HitPredict

Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1
Gene: LUZP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4684 Hs			1 1076
+	Hs
		1068617 PLEC_HUMAN (1-4684): 0: 1783: 100.00		MY18A_HUMAN (4-516): 2.88e-29: 129: 11.91
+	Hs
		148841 PLEC_HUMAN (1-4684): 0: 1783: 100.00		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Mm
		93578 PLEC_MOUSE (1-4684): 0: 1747: 93.29		DESP_MOUSE (110-643): 8.06e-23: 108: 10.26
+	Hs
		724839 PLEC_HUMAN (1-4684): 0: 1783: 100.00		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Hs
		1068536 PLEC_HUMAN (1-4684): 0: 1783: 100.00		PLEC_HUMAN (35-503): 1.33e-11: 71.4: 16.50
+	Hs
		1068548 PLEC_HUMAN (1-4684): 0: 1783: 100.00		GRDN_HUMAN (10-513): 1.42e-09: 64.9: 17.82
+	Hs
		1068551 PLEC_HUMAN (1-4684): 0: 1783: 100.00		FIL1L_HUMAN (208-656): 4.26e-09: 62.8: 12.71
+	Hs
		148722 ACTN3_HUMAN (166-893): 2.36e-146: 484: 25.79		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		148330 SPTB1_HUMAN (151-2274): 6.68e-124: 442: 17.12		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		148339 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		521484 ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Hs
		148591 EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		885258 EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75		MRCKA_HUMAN (1-362): 2.6e-17: 90.2: 17.96
+	Hs
		164647 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		MY18A_HUMAN (4-516): 2.88e-29: 129: 11.91
+	Hs
		148142 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		148690 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		CTRO_HUMAN (2-458): 4.05e-25: 115: 14.56
+	Hs
		164575 SPTN2_HUMAN (1390-3166): 2.85e-25: 118: 12.24		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83
+	Mm
		513811 DMD_MOUSE (1215-3224): 1.33e-25: 120: 9.43		FLIP1_MOUSE (230-668): 1.77e-09: 64.4: 9.42
+	Mm
		513821 DMD_MOUSE (1215-3224): 1.33e-25: 120: 9.43		PLEC_MOUSE (3-390): 6.63e-09: 62.5: 19.86
+	Hs
		724781 SPTB2_HUMAN (1531-3349): 2.4e-17: 92.7: 9.53		MYH9_HUMAN (385-763): 9.36e-12: 71.6: 8.83