Protein: LKH1
Dual specificity protein kinase lkh1 (EC 2.7.12.1)

Gene: LKH1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 78
UniProt ID: Q10156

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000920 - septum digestion after cytokinesis
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

149433

PMP1
Tyrosine-protein phosphatase pmp1

2

3

High-throughput

0.791

High

151228

CSX1
RNA-binding post-transcriptional regulator csx1

1

6

Small-scale

0.725

High

151827

RSD1
RNA-binding protein rsd1

1

15

High-throughput

0.647

High

153783

WIS4
MAP kinase kinase kinase wis4

1

9

High-throughput

0.647

High

205934

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22

1

5

High-throughput

0.647

High

534537

ACT
Actin

1

4

High-throughput

0.647

High

836495

GAR2
Protein gar2

1

14

High-throughput

0.647

High

1082733

LKH1
Dual specificity protein kinase lkh1

1

16

High-throughput

0.647

High

1082748

RSV1
Zinc finger protein rsv1

1

1

High-throughput

0.647

High

152474

MAK2
Peroxide stress-activated histidine kinase mak2

1

0

High-throughput

0.614

High

206955

CIP1
RNA-binding post-transcriptional regulator cip1

1

0

High-throughput

0.614

High

207008

YBP8
Uncharacterized ABC transporter ATP-binding protein C16H5.08c

1

0

High-throughput

0.614

High

1082740

INCE
Inner centromere protein pic1

1

0

High-throughput

0.614

High

154009

SCE3
Probable RNA-binding protein sce3

1

15

High-throughput

0.579

High

267666

SCW1
Cell wall integrity protein scw1

1

7

High-throughput

0.579

High

267922

POB1
Protein pob1

1

8

High-throughput

0.579

High

1082747

YN8E
Pumilio domain-containing protein P35G2.14

1

1

High-throughput

0.579

High

823555

RUM1
Cyclin-dependent kinase inhibitor rum1

1

1

Small-scale

0.578

High

1068484

TUP11
Transcriptional repressor tup11

1

10

Small-scale

0.578

High

1082755

TUP12
Transcriptional repressor tup12

1

8

Small-scale

0.578

High

1018105

VIPI
Protein vip1

1

0

High-throughput

0.541

High

148839

SRW1
WD repeat-containing protein srw1

1

16

High-throughput

0.501

High

267599

SNUT3
U4/U6.U5 tri-snRNP-associated protein 3-like protein C162.01c

1

1

High-throughput

0.501

High

267707

YQC1
Uncharacterized protein C1739.01

1

3

High-throughput

0.501

High

268083

MSH2
DNA mismatch repair protein msh2

1

1

High-throughput

0.501

High

268825

TFH47
General transcription and DNA repair factor IIH subunit ssl1

1

1

High-throughput

0.501

High

314312

PSA1
Probable proteasome subunit alpha type-1

1

5

High-throughput

0.501

High

661360

PP2A2
Major serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

10

High-throughput

0.501

High

1009066

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.501

High

1068488

DBP10
ATP-dependent RNA helicase dbp10

1

6

High-throughput

0.501

High

1068548

THO2
THO complex subunit 2

1

5

High-throughput

0.501

High

1082722

YAT2
Uncharacterized protein C1D4.02c

1

3

High-throughput

0.501

High

1082734

SF3B1
U2 snRNP component prp10

1

4

High-throughput

0.501

High

1082737

PSA4
Probable proteasome subunit alpha type-4

1

5

High-throughput

0.501

High

1082738

IF4G
Eukaryotic translation initiation factor 4 gamma

1

6

High-throughput

0.501

High

1082744

ASE1
Anaphase spindle elongation protein 1

1

10

High-throughput

0.501

High

1082750

UBP9
Probable ubiquitin carboxyl-terminal hydrolase 9

1

8

High-throughput

0.501

High

1082754

SNF21
Chromatin structure-remodeling complex subunit snf21

1

2

High-throughput

0.501

High

1082757

BYE1
Transcription factor bye1

1

4

High-throughput

0.501

High

1082758

YOP2
N-terminal acetyltransferase A complex subunit-like protein C418.02

1

2

High-throughput

0.501

High

151773

DCP2
mRNA decapping complex subunit 2

1

0

High-throughput

0.480

High

152022

SPT5
Transcription elongation factor spt5

1

0

High-throughput

0.480

High

206938

OGA1
Ribosome-associated protein oga1

1

0

High-throughput

0.480

High

238304

METK
S-adenosylmethionine synthase

1

0

High-throughput

0.480

High

267585

SET11
Ribosomal lysine N-methyltransferase set11

1

0

High-throughput

0.480

High

267617

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.480

High

267697

MU123
Meiotically up-regulated gene 123 protein

1

0

High-throughput

0.480

High

267857

YCV2
Uncharacterized transcriptional regulatory protein C777.02

1

0

High-throughput

0.480

High

313734

MPR1
Multistep phosphorelay regulator 1

1

0

High-throughput

0.480

High

896086

HSP9
Heat shock protein hsp9

1

0

High-throughput

0.480

High

1082739

YDG7
Uncharacterized oxidoreductase C26F1.07

1

0

High-throughput

0.480

High

1082741

THRC
Threonine synthase

1

0

High-throughput

0.480

High

1082742

SST6
ESCRT-I complex subunit vps23

1

0

High-throughput

0.480

High

1082746

ASK1
DASH complex subunit ask1

1

0

High-throughput

0.480

High

1082749

SNF30
SWI/SNF chromatin-remodeling complex subunit snf30

1

0

High-throughput

0.480

High

1082751

TF211
Transposon Tf2-11 polyprotein

1

0

High-throughput

0.480

High

153807

CYK3
cytokinesis protein 3

1

1

High-throughput

0.457

High

206115

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.457

High

237962

MAP2
Methionine aminopeptidase 2

1

2

High-throughput

0.457

High

268464

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.457

High

314208

RGA7
Probable Rho-GTPase-activating protein 7

1

5

High-throughput

0.457

High

1068587

CDC15
Cell division control protein 15

1

2

High-throughput

0.457

High

1082735

IMP2
Septation protein imp2

1

2

High-throughput

0.457

High

1082736

DPH2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

1

1

High-throughput

0.457

High

1082743

PUB1
E3 ubiquitin-protein ligase pub1

1

8

High-throughput

0.457

High

1082745

UBP2
Probable ubiquitin carboxyl-terminal hydrolase 2

1

11

High-throughput

0.457

High

1082756

RGA9
Probable Rho-GTPase-activating protein 9

1

2

High-throughput

0.457

High

150896

YDY2
Uncharacterized protein C11E3.02c

1

0

High-throughput

0.261

Low

153306

MDE5
Alpha-amylase mde5

1

0

High-throughput

0.261

Low

206846

YF75
Uncharacterized protein C3G9.05

1

0

High-throughput

0.261

Low

207035

YBPC
Uncharacterized protein C16H5.12c

1

0

High-throughput

0.261

Low

268314

MSY1
Mechanosensitive ion channel protein Msy1

1

0

High-throughput

0.261

Low

313647

SUR2
Sphingolipid C4-hydroxylase sur2

1

0

High-throughput

0.261

Low

314363

YCDA
UPF0619 GPI-anchored membrane protein C1322.10

1

0

High-throughput

0.261

Low

1068678

YAG9
Uncharacterized protein C12G12.09

1

0

High-throughput

0.261

Low

1082752

RS26A
Small ribosomal subunit protein eS26A

1

0

High-throughput

0.261

Low

1082753

PFD2
Probable prefoldin subunit 2

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025