Protein: DBP6
ATP-dependent RNA helicase DBP6 (EC 3.6.4.13) (DEAD box protein 6)

Gene: DBP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 81
UniProt ID: P53734

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710906

URB1
Nucleolar pre-ribosomal-associated protein 1

7

2

Small-scale

0.748

High

811783

URB2
Nucleolar pre-ribosomal-associated protein 2

7

1

Small-scale

0.742

High

755104

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.687

High

744220

MAK5
ATP-dependent RNA helicase MAK5

1

15

Small-scale

0.618

High

754154

CIC1
Proteasome-interacting protein CIC1

1

5

High-throughput

0.618

High

810887

MTR4
ATP-dependent RNA helicase DOB1

1

14

Small-scale

0.618

High

864503

DHR1
Probable ATP-dependent RNA helicase DHR1

1

14

High-throughput

0.618

High

864507

RSA3
Ribosome assembly protein 3

3

0

Small-scale

0.613

High

864511

NOP8
60S ribosome subunit biogenesis protein NOP8

3

0

Small-scale

0.606

High

512210

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.601

High

732233

RRP14
Ribosomal RNA-processing protein 14

2

2

High-throughput

0.594

High

776472

RLP7
Ribosome biogenesis protein RLP7

2

11

High-throughput

0.594

High

797373

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

2

High-throughput

0.594

High

864500

NOG2
Nucleolar GTP-binding protein 2

2

9

High-throughput

0.594

High

864514

RRS1
Regulator of ribosome biosynthesis

2

2

High-throughput

0.594

High

864499

DBP6
ATP-dependent RNA helicase DBP6

1

14

Small-scale

0.590

High

864509

DBP9
ATP-dependent RNA helicase DBP9

1

16

Small-scale

0.590

High

748669

ENP1
Essential nuclear protein 1

2

7

High-throughput

0.584

High

864516

MAK21
Ribosome biogenesis protein MAK21

2

14

Small-scale

0.584

High

864520

NOP58
Nucleolar protein 58

2

10

High-throughput

0.584

High

145765

RL36B
Large ribosomal subunit protein eL36B

1

4

High-throughput

0.575

High

356627

H4
Histone H4

1

10

High-throughput

0.575

High

485790

IF4A
ATP-dependent RNA helicase eIF4A

1

16

High-throughput

0.575

High

701525

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.553

High

494597

HSP72
Heat shock protein SSA2

2

16

High-throughput

0.552

High

691399

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

7

High-throughput

0.541

High

676249

XPO1
Exportin-1

1

19

High-throughput

0.536

High

549449

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.515

High

597870

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.515

High

635143

YCQ6
Uncharacterized protein YCR016W

1

1

High-throughput

0.515

High

864513

ESA1
Histone acetyltransferase ESA1

1

6

Small-scale

0.501

High

535066

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.479

High

630236

RRP43
Exosome complex component RRP43

1

3

High-throughput

0.479

High

662927

TF2B
Transcription initiation factor IIB

1

8

High-throughput

0.479

High

680902

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

688352

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

5

High-throughput

0.479

High

754888

SSF1
Ribosome biogenesis protein SSF1

1

5

High-throughput

0.479

High

764213

NOC2
Nucleolar complex protein 2

1

3

High-throughput

0.479

High

778826

NOP2
25S rRNA

1

11

Small-scale

0.479

High

792527

UTP10
U3 small nucleolar RNA-associated protein 10

1

6

High-throughput

0.479

High

860844

PESC
Pescadillo homolog

1

5

High-throughput

0.479

High

864501

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

864504

UTP14
U3 small nucleolar RNA-associated protein 14

1

5

High-throughput

0.479

High

864508

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

4

High-throughput

0.479

High

864510

NOC4
Nucleolar complex protein 4

1

14

High-throughput

0.479

High

864512

SGO1
Shugoshin

1

6

High-throughput

0.479

High

864515

NOP53
Ribosome biogenesis protein NOP53

1

4

High-throughput

0.479

High

864517

RIO1
Serine/threonine-protein kinase RIO1

1

13

High-throughput

0.479

High

342077

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.445

High

492002

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

544175

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.445

High

556204

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

566634

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

641020

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.445

High

695220

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

705488

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.445

High

733885

RPF2
Ribosome biogenesis protein RPF2

1

3

High-throughput

0.445

High

769071

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

772908

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.445

High

796920

GCN20
Protein GCN20

1

2

High-throughput

0.445

High

829648

RL4B
Large ribosomal subunit protein uL4B

1

8

High-throughput

0.445

High

864505

RRP5
rRNA biogenesis protein RRP5

1

12

High-throughput

0.445

High

864518

RL7B
Large ribosomal subunit protein uL30B

1

11

High-throughput

0.445

High

637151

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

4

High-throughput

0.437

High

762432

LAA1
AP-1 accessory protein LAA1

1

7

High-throughput

0.437

High

860333

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.437

High

864502

NUM1
Nuclear migration protein NUM1

1

11

High-throughput

0.437

High

864519

YO093
Uncharacterized protein YOR093C

1

1

High-throughput

0.437

High

340226

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

411050

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.426

High

424639

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

454418

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

399576

RLA0
Large ribosomal subunit protein uL10

1

7

High-throughput

0.407

High

687441

EF2
Elongation factor 2

1

5

High-throughput

0.407

High

864506

PAL1
Protein PAL1

1

0

High-throughput

0.249

Low

333870

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

341102

CBPY
Carboxypeptidase Y

1

0

High-throughput

0.232

Low

360979

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

421672

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

785137

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024