HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: TET2 (Q6N021)
Methylcytosine dioxygenase TET2 (EC 1.14.11.80)
Gene: TET2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 471 Hs			1 2002
+	Hs
		1154477 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		516558 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		195831 NONO_HUMAN (1-471): 1.15e-97: 303: 100.00		TET3_HUMAN (890-2002): 0: 854: 38.53
+	Hs
		195836 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		TET3_HUMAN (890-2002): 0: 854: 38.53
+	Hs
		1244992 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06