Protein: PHB1
Prohibitin 1 (Protein l(2)37Cc)

Gene: PHB1
Organism: Drosophila melanogaster
Interactions: 108
UniProt ID: P24156

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0007005 - mitochondrion organization
GO:0035632 - mitochondrial prohibitin complex
GO:0071456 - cellular response to hypoxia

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

663956

Q0E924
Prohibitin

2

14

High-throughput

0.737

High

663980

VDAC
Voltage-dependent anion-selective channel

2

9

High-throughput

0.571

High

664008

Q9VMW2
Reticulon-like protein

2

3

High-throughput

0.533

High

649001

ANX10
Annexin B10

2

3

High-throughput

0.521

High

663954

PDI
Protein disulfide-isomerase

2

4

High-throughput

0.521

High

663961

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

3

High-throughput

0.521

High

663977

OLA1
Obg-like ATPase 1

2

2

High-throughput

0.521

High

664007

Q9VMV9
Reticulon-like protein

2

3

High-throughput

0.520

High

663981

Q95RF6
LD34461p

1

1

High-throughput

0.479

High

663992

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

3

High-throughput

0.479

High

663997

Q9VIQ8
Cytochrome c oxidase subunit 4

1

2

High-throughput

0.479

High

664000

ZUC
Mitochondrial cardiolipin hydrolase

1

3

High-throughput

0.479

High

663988

Q9VAC1
GM14349p

1

0

High-throughput

0.464

High

664003

Q9VL58
LP07441p

1

3

High-throughput

0.464

High

664011

RAB26
Ras-related protein Rab-26

1

10

High-throughput

0.464

High

305631

IPYR
Inorganic pyrophosphatase

1

2

High-throughput

0.445

High

663948

CALR
Calreticulin

1

4

High-throughput

0.445

High

663960

ATP5H
ATP synthase subunit d, mitochondrial

1

2

High-throughput

0.445

High

663963

ATPO
ATP synthase subunit O, mitochondrial

1

4

High-throughput

0.445

High

663976

Q8IRD3
Glutathione peroxidase

1

1

High-throughput

0.445

High

663990

Q9VD29
small monomeric GTPase

1

14

High-throughput

0.445

High

664018

SUN
Protein stunted

1

1

High-throughput

0.445

High

118776

M9NFI9
Neurabin-1

1

4

High-throughput

0.442

High

121944

M9PH36
Zinc finger DHHC-type containing 8, isoform E

1

2

High-throughput

0.439

High

664024

Q9W1B5
Glycerol-3-phosphate acyltransferase 4, isoform C

1

5

Small-scale

0.439

High

57742

A1ZB77
Uncharacterized protein, isoform J

1

1

High-throughput

0.437

High

68890

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.437

High

609357

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.437

High

664004

Q9VL69
Translocon-associated protein subunit gamma

1

2

High-throughput

0.437

High

664014

Q9VSE8
UDP-glucuronic acid decarboxylase 1

1

2

High-throughput

0.437

High

664015

Q9VTY2
Uncharacterized protein, isoform A

1

1

High-throughput

0.437

High

664022

Q9W0M4
Endoplasmic reticulum transmembrane protein

1

2

High-throughput

0.437

High

663962

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.426

High

664027

Q9W2X6
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.426

High

664028

ZDHC8
Palmitoyltransferase ZDHHC8

1

2

High-throughput

0.417

High

57520

A1ZB71
Glutathione S transferase E6

1

2

High-throughput

0.407

High

86455

B9EQV3
Endoplasmic reticulum transmembrane protein

1

2

High-throughput

0.407

High

197045

O18332
FI01544p

1

6

High-throughput

0.407

High

426624

HP1
Heterochromatin protein 1

1

2

High-throughput

0.407

High

451730

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

2

High-throughput

0.407

High

561558

SPTCA
Spectrin alpha chain

1

2

High-throughput

0.407

High

578033

ENO
Enolase

1

3

High-throughput

0.407

High

614885

SYB
Synaptobrevin

1

2

High-throughput

0.407

High

616503

ARM
Armadillo segment polarity protein

1

8

High-throughput

0.407

High

626981

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.407

High

648855

ANXB9
Annexin B9

1

3

High-throughput

0.407

High

654832

MA205
205 kDa microtubule-associated protein

1

1

High-throughput

0.407

High

657725

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

2

High-throughput

0.407

High

663950

PNUT
Protein peanut

1

7

High-throughput

0.407

High

663951

SEPT1
Septin-1

1

7

High-throughput

0.407

High

663952

MOEH
Moesin/ezrin/radixin homolog 1

1

3

High-throughput

0.407

High

663953

SEPT2
Septin-2

1

7

High-throughput

0.407

High

663955

GELS
Gelsolin

1

2

High-throughput

0.407

High

663957

MY31D
Unconventional myosin ID

1

7

High-throughput

0.407

High

663958

MY61F
Unconventional myosin IC

1

5

High-throughput

0.407

High

663959

FLII
Protein flightless-1

1

2

High-throughput

0.407

High

663964

U2AF2
Splicing factor U2AF 50 kDa subunit

1

13

High-throughput

0.407

High

663965

Q6QU65
ADAM metalloprotease

1

4

High-throughput

0.407

High

663966

Q7JRJ9
Inner centromere protein, isoform A

1

2

High-throughput

0.407

High

663968

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.407

High

663969

Q7K3J0
T-complex protein 1 subunit theta

1

7

High-throughput

0.407

High

663970

Q7KKI0
T-complex protein 1 subunit epsilon

1

6

High-throughput

0.407

High

663971

Q7KLX3
Translocon-associated protein subunit delta

1

2

High-throughput

0.407

High

663972

TERA
Transitional endoplasmic reticulum ATPase TER94

1

3

High-throughput

0.407

High

663973

Q7KTJ7
Basigin, isoform G

1

5

High-throughput

0.407

High

663974

Q8IQZ7
FI19014p1

1

3

High-throughput

0.407

High

663975

Q8IR86
Bifocal, isoform B

1

1

High-throughput

0.407

High

663982

FAXC
Failed axon connections

1

4

High-throughput

0.407

High

663983

Q960C7
NADP-retinol dehydrogenase

1

5

High-throughput

0.407

High

663984

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

2

High-throughput

0.407

High

663985

JIL1
Chromosomal serine/threonine-protein kinase JIL-1

1

6

High-throughput

0.407

High

663986

ANLN
Anillin

1

4

High-throughput

0.407

High

663987

FRIL
Ferritin light chain

1

2

High-throughput

0.407

High

663989

CISD2
CDGSH iron-sulfur domain protein

1

1

High-throughput

0.407

High

663991

FLNA
Filamin-A

1

7

High-throughput

0.407

High

663993

TWF
Twinfilin

1

1

High-throughput

0.407

High

663994

TEBPH
Cytosolic Prostaglandin E synthase

1

1

High-throughput

0.407

High

663995

ADAL
Adenosine deaminase-like protein

1

1

High-throughput

0.407

High

663996

NESD
Protein nessun dorma

1

1

High-throughput

0.407

High

663999

Q9VJW9
ADAM10 endopeptidase

1

4

High-throughput

0.407

High

664001

AURKB
Aurora kinase B

1

5

High-throughput

0.407

High

664002

EF1D
Probable elongation factor 1-delta

1

2

High-throughput

0.407

High

664005

AK200
A-kinase anchor protein 200

1

4

High-throughput

0.407

High

664009

Q9VN44
FI07923p

1

8

High-throughput

0.407

High

664010

Q9VNX6
LD06749p

1

3

High-throughput

0.407

High

664013

Q9VQL1
serine--tRNA ligase

1

3

High-throughput

0.407

High

664016

RS10B
Small ribosomal subunit protein eS10B

1

3

High-throughput

0.407

High

664019

Q9VXN3
LD07988p

1

2

High-throughput

0.407

High

664020

Q9VZI1
Transgelin

1

2

High-throughput

0.407

High

664021

Q9W0L7
ubiquitinyl hydrolase 1

1

1

High-throughput

0.407

High

664023

SND1
Staphylococcal nuclease domain-containing protein 1

1

5

High-throughput

0.407

High

664025

Q9W1G6
Kazachoc, isoform A

1

5

High-throughput

0.407

High

119689

M9PB45
Uncharacterized protein, isoform B

1

0

High-throughput

0.249

Low

305096

PELI
Protein pellino

1

0

High-throughput

0.249

Low

664012

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

0

High-throughput

0.249

Low

543334

FCP3C
Follicle cell protein 3C-1

1

0

High-throughput

0.238

Low

55216

A1Z995
Sequoia, isoform A

1

0

High-throughput

0.232

Low

69061

A8JRH3
FI20012p1

1

0

High-throughput

0.232

Low

643287

CPD1
Chromosomal protein D1

1

0

High-throughput

0.232

Low

663947

PROF
Profilin

1

0

High-throughput

0.232

Low

663949

PDM1
Protein nubbin

1

0

High-throughput

0.232

Low

663967

Q7K0D3
CG12909 protein

1

0

High-throughput

0.232

Low

663978

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.232

Low

663979

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

663998

Q9VJ59
PRA1 family protein

1

0

High-throughput

0.232

Low

664006

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.232

Low

664017

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.232

Low

664026

Q9W258
Babos, isoform A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025