HitPredict

Interactor 1: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 471 Hs			1 2752
+	Hs
		516749 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		613619 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1069770 NONO_HUMAN (1-471): 1.15e-97: 303: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1127659 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		516546 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		613557 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1069707 NONO_HUMAN (1-471): 1.15e-97: 303: 100.00		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		965106 NONO_HUMAN (1-471): 1.15e-97: 303: 100.00		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		1031405 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		516609 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820908 PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		820986 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516406 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1263596 PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516766 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516595 PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		965152 PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		613371 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		613570 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		613628 SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11