HitPredict

Interactor 1: PTPRK (Q15262)
Receptor-type tyrosine-protein phosphatase kappa (Protein-tyrosine phosphatase kappa) (R-PTP-kappa) (EC 3.1.3.48)
Gene: PTPRK

Interactor 2: AMGO3 (Q86WK7)
Amphoterin-induced protein 3 (AMIGO-3) (Alivin-3)
Gene: AMIGO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	I-set~LRR_8
Common GO terms	GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1439 Hs			1 504
+	Hs
		1069952 PTPRK_HUMAN (26-1439): 0: 1191: 100.00		PXDN_HUMAN (279-473): 3.46e-31: 130: 13.93
+	Hs
		1069940 PTPRK_HUMAN (26-1439): 0: 1191: 100.00		AMGO1_HUMAN (10-146): 1.14e-16: 84.6: 23.97
+	Hs
		1069962 PTPRK_HUMAN (26-1439): 0: 1191: 100.00		LRIG1_HUMAN (279-445): 3.19e-12: 71.5: 15.39
+	Hs
		1069932 PTPRK_HUMAN (26-1439): 0: 1191: 100.00		LRIG3_HUMAN (279-374): 1.51e-09: 62.6: 14.43
+	Hs
		616984 PTPRD_HUMAN (103-939): 2.78e-70: 263: 12.10		LRRN1_HUMAN (1-371): 8.21e-56: 200: 16.48
+	Hs
		259496 PTPRD_HUMAN (103-939): 2.78e-70: 263: 12.10		LRRN2_HUMAN (9-504): 6.51e-45: 169: 16.37
+	Hs
		299564 PTPRO_HUMAN (1162-1433): 5.11e-94: 333: 30.22		LRIG2_HUMAN (9-341): 4.69e-19: 93: 17.18
+	Hs
		616988 PTPRD_HUMAN (103-939): 2.78e-70: 263: 12.10		LIGO2_HUMAN (41-372): 6.93e-40: 154: 20.56
+	Hs
		200339 PTPRD_HUMAN (103-939): 2.78e-70: 263: 12.10		LRRT2_HUMAN (65-241): 7.93e-11: 66.2: 31.67
+	Rn
		73316 PTPRS_RAT (299-939): 2.7e-22: 106: 8.75		LRRT4_RAT (34-199): 2e-13: 74.7: 31.33
+	Hs
		1032001 PTPRS_HUMAN (264-939): 5.82e-22: 105: 9.34		LRRT4_HUMAN (34-199): 2e-13: 74.7: 31.33