Protein: 5MP1
eIF5-mimic protein 1 (Basic leucine zipper and W2 domain-containing protein 2)

Gene: 5MP1, BZW2
Organism: Homo sapiens
Interactions: 115
UniProt ID: Q9Y6E2

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006446 - regulation of translational initiation
GO:0016020 - membrane
GO:0045296 - cadherin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1271322

5MP2
eIF5-mimic protein 2

5

3

High-throughput

0.925

High

760788

CD68
Macrosialin

3

1

High-throughput

0.667

High

1381416

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

3

4

High-throughput

0.662

High

322076

ENDD1
Endonuclease domain-containing 1 protein

3

0

High-throughput

0.634

High

1334340

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

1

High-throughput

0.628

High

1461121

NXT1
NTF2-related export protein 1

2

4

High-throughput

0.628

High

332729

LYPD3
Ly6/PLAUR domain-containing protein 3

3

1

High-throughput

0.609

High

1294874

STX12
Syntaxin-12

3

1

High-throughput

0.609

High

1413716

TMM43
Transmembrane protein 43

3

1

High-throughput

0.604

High

1436026

PACC1
Proton-activated chloride channel

3

2

High-throughput

0.604

High

1490674

EXOG
Nuclease EXOG, mitochondrial

3

2

High-throughput

0.604

High

327522

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.602

High

1358495

CANT1
Soluble calcium-activated nucleotidase 1

2

0

High-throughput

0.602

High

1430270

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.602

High

1124247

EI2BA
Translation initiation factor eIF2B subunit alpha

2

9

Small-scale

0.595

High

243446

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

939993

TPTE
Putative tyrosine-protein phosphatase TPTE

2

1

High-throughput

0.584

High

438114

GLPB
Glycophorin-B

2

3

High-throughput

0.574

High

1278166

MAVS
Mitochondrial antiviral-signaling protein

2

1

High-throughput

0.574

High

1389732

TV23C
Golgi apparatus membrane protein TVP23 homolog C

2

1

High-throughput

0.574

High

262348

SCN2B
Sodium channel regulatory subunit beta-2

2

1

High-throughput

0.558

High

171627

S27A2
Long-chain fatty acid transport protein 2

2

6

High-throughput

0.549

High

374314

RASN
GTPase NRas

1

5

High-throughput

0.536

High

388345

GLPA
Glycophorin-A

1

3

High-throughput

0.536

High

585836

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

3

High-throughput

0.536

High

658988

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

1

High-throughput

0.536

High

909266

NEK4
Serine/threonine-protein kinase Nek4

1

2

High-throughput

0.536

High

939475

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

9

High-throughput

0.536

High

970206

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

973643

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

1310573

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1360546

PSPC1
Paraspeckle component 1

1

7

High-throughput

0.536

High

1460840

CC018
Uncharacterized protein C3orf18

1

1

High-throughput

0.536

High

1490545

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

1

High-throughput

0.536

High

220826

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

1

High-throughput

0.515

High

1399190

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.513

High

891923

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.508

High

627744

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

7

Small-scale

0.501

High

955804

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.501

High

1121935

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

Small-scale

0.501

High

1417769

EIF2A
Eukaryotic translation initiation factor 2A

1

8

Small-scale

0.501

High

389588

FINC
Fibronectin

1

3

High-throughput

0.489

High

520719

RRAS
Ras-related protein R-Ras

1

6

High-throughput

0.489

High

914385

EFNA4
Ephrin-A4

1

4

High-throughput

0.489

High

1101720

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

9

High-throughput

0.489

High

1228794

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

2

High-throughput

0.489

High

1249882

BTNL9
Butyrophilin-like protein 9

1

2

High-throughput

0.489

High

1491802

NPTN
Neuroplastin

1

2

High-throughput

0.489

High

1491826

SAR1B
Small COPII coat GTPase SAR1B

1

3

High-throughput

0.489

High

364101

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

556450

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

607282

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

643170

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

4

High-throughput

0.479

High

890178

EI2BB
Translation initiation factor eIF2B subunit beta

1

9

High-throughput

0.479

High

935371

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

999012

H31
Histone H3.1

1

2

High-throughput

0.479

High

1067893

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1256312

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1280649

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

1434371

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.479

High

1458576

HDAC6
Protein deacetylase HDAC6

1

3

High-throughput

0.479

High

1458859

DUX4
Double homeobox protein 4

1

1

High-throughput

0.479

High

1459497

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1460175

EI2BD
Translation initiation factor eIF2B subunit delta

1

8

High-throughput

0.479

High

1490736

FND3A
Fibronectin type-III domain-containing protein 3A

1

5

High-throughput

0.479

High

1048339

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

1135881

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1330457

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

186152

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.457

High

136569

GOLI4
Golgi integral membrane protein 4

1

2

High-throughput

0.445

High

316586

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

1

High-throughput

0.445

High

1144691

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

1

High-throughput

0.445

High

1240996

S27A4
Long-chain fatty acid transport protein 4

1

6

High-throughput

0.445

High

1292386

UN93A
Protein unc-93 homolog A

1

2

High-throughput

0.445

High

1405355

P2RX4
P2X purinoceptor 4

1

1

High-throughput

0.445

High

844146

HD
Huntingtin

1

0

High-throughput

0.438

High

219034

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

412905

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

590164

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

697002

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

733521

GP183
G-protein coupled receptor 183

1

8

High-throughput

0.437

High

769648

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

957580

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.437

High

1142051

EEA1
Early endosome antigen 1

1

3

High-throughput

0.437

High

1164105

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

2

High-throughput

0.437

High

1249381

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

1367711

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1430498

RAB1B
Ras-related protein Rab-1B

1

1

High-throughput

0.437

High

1433714

EMRE
Essential MCU regulator, mitochondrial

1

1

High-throughput

0.437

High

1453076

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.437

High

1460212

IPO11
Importin-11

1

6

High-throughput

0.437

High

1461955

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.437

High

166465

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

420058

B3A2
Anion exchange protein 2

1

0

High-throughput

0.426

High

904225

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

934304

BI1
Bax inhibitor 1

1

0

High-throughput

0.426

High

1083167

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.426

High

1275437

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.426

High

1324405

ABD12
Lysophosphatidylserine lipase ABHD12

1

0

High-throughput

0.426

High

253918

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.407

High

1111403

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.407

High

1448632

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

1

High-throughput

0.407

High

1459049

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.407

High

1490853

S27A5
Long-chain fatty acid transport protein 5

1

6

High-throughput

0.407

High

887391

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.373

High

1439557

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

3

0

High-throughput

0.345

High

835430

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

0

High-throughput

0.328

High

1388615

OMA1
Metalloendopeptidase OMA1, mitochondrial

2

0

High-throughput

0.328

High

280973

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

1384742

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

502613

H2A1
Histone H2A type 1

1

0

High-throughput

0.249

Low

1339783

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

1453729

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low

1333528

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.232

Low

1381048

S35B4
Nucleotide sugar transporter SLC35B4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025