HitPredict

Interactor 1: G5EES2 (G5EES2)
Moesin/ezrin/radixin homolog 1
Gene: erm-1

Interactor 2: LET23 (P24348)
Receptor tyrosine-protein kinase let-23 (EC 2.7.10.1) (Lethal protein 23)
Gene: let-23

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24785082
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0002119 - nematode larval development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 563 Ce			1 1323
+	Hs
		665555 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		EPHB2_HUMAN (478-1322): 1.08e-180: 564: 17.39
+	Hs
		640048 MOES_HUMAN (2-563): 1.29e-146: 436: 54.42		EPHB2_HUMAN (478-1322): 1.08e-180: 564: 17.39
+	Hs
		546943 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		EPHA2_HUMAN (478-1190): 8.61e-167: 525: 18.92
+	Hs
		719689 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		EPHA5_HUMAN (511-1181): 1.57e-164: 521: 18.61
+	Hs
		383579 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		ERBB2_HUMAN (382-1323): 1.51e-139: 459: 21.61
+	Hs
		383651 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		ERBB2_HUMAN (382-1323): 1.51e-139: 459: 21.61
+	Hs
		383621 MOES_HUMAN (2-563): 1.29e-146: 436: 54.42		ERBB2_HUMAN (382-1323): 1.51e-139: 459: 21.61
+	Hs
		383650 MERL_HUMAN (2-563): 6.75e-144: 430: 41.80		ERBB2_HUMAN (382-1323): 1.51e-139: 459: 21.61
+	Hs
		547018 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		FAK1_HUMAN (846-1242): 4.27e-107: 365: 30.33
+	Hs
		434145 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		RET_HUMAN (601-1174): 1.45e-107: 368: 21.75
+	Hs
		507828 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		FGFR1_HUMAN (887-1139): 2.53e-47: 185: 35.90
+	Hs
		507885 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		FGFR1_HUMAN (887-1139): 2.53e-47: 185: 35.90
+	Hs
		609192 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		FGFR3_HUMAN (881-1139): 1.83e-47: 185: 36.88
+	Hs
		507865 MOES_HUMAN (2-563): 1.29e-146: 436: 54.42		FGFR1_HUMAN (887-1139): 2.53e-47: 185: 35.90
+	Dm
		448235 MOEH_DROME (1-563): 3.69e-153: 453: 59.17		INSR_DROME (366-678): 3.67e-39: 162: 22.63
+	Hs
		337871 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		EGFR_HUMAN (29-329): 5.87e-35: 147: 20.85
+	Hs
		338027 RADI_HUMAN (2-563): 4.66e-148: 440: 52.88		EGFR_HUMAN (29-329): 5.87e-35: 147: 20.85
+	Hs
		338026 MERL_HUMAN (2-563): 6.75e-144: 430: 41.80		EGFR_HUMAN (29-329): 5.87e-35: 147: 20.85
+	Hs
		546927 EZRI_HUMAN (2-563): 3.27e-154: 455: 53.05		ERBB3_HUMAN (377-750): 3.6e-27: 122: 18.74
+	Hs
		435541 MOES_HUMAN (2-563): 1.29e-146: 436: 54.42		IGF1R_HUMAN (367-669): 1.14e-23: 111: 20.49