HitPredict

Interactor 1: UNC40 (G5EF96)
Netrin receptor unc-40 (Uncoordinated protein 40)
Gene: unc-40

Interactor 2: Q7KPP4 (Q7KPP4)
CRAL-TRIO domain-containing protein (Guanine nucleotide exchange factor UNC-73B)
Gene: unc-73

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	17237778, 20627078
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RhoGEF~fn3
Common GO terms	GO:0001764 - neuron migration GO:0007411 - axon guidance
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1415 Ce			1 1638
+	Dm
		53812 A1Z921_DROME (14-843): 1.17e-63: 240: 16.50		Q7YZA0_DROME (1139-1528): 3.65e-79: 278: 23.31
+	Hs
		279860 PTPRS_HUMAN (4-1121): 9.8e-89: 321: 16.55		TRIO_HUMAN (1194-1638): 1.38e-34: 147: 21.60
+	Hs
		279833 PTPRF_HUMAN (14-949): 2.31e-59: 227: 15.35		TRIO_HUMAN (1194-1638): 1.38e-34: 147: 21.60
+	Hs
		1137771 TITIN_HUMAN (3-157): 9.27e-11: 69.5: 12.82		OBSCN_HUMAN (1193-1513): 3.04e-76: 284: 22.52
+	Hs
		234502 DSCAM_HUMAN (236-1402): 1.81e-37: 156: 10.46		SPTB2_HUMAN (492-1296): 2.04e-43: 176: 10.46
+	Hs
		224694 DSCAM_HUMAN (236-1402): 1.81e-37: 156: 10.46		KALRN_HUMAN (81-1588): 3.59e-38: 159: 11.32
+	Hs
		234520 DSCAM_HUMAN (236-1402): 1.81e-37: 156: 10.46		PLEC_HUMAN (103-1160): 1.1e-28: 128: 8.54
+	Hs
		279839 PTPRD_HUMAN (730-1398): 2.84e-31: 136: 10.07		TRIO_HUMAN (1194-1638): 1.38e-34: 147: 21.60
+	Hs
		855816 TITIN_HUMAN (3-157): 9.27e-11: 69.5: 12.82		VAV2_HUMAN (1134-1634): 3.62e-52: 201: 13.04
+	Hs
		234503 DSCAM_HUMAN (236-1402): 1.81e-37: 156: 10.46		DYST_HUMAN (225-1201): 1.35e-10: 69: 9.69