Protein: NUDT5
ADP-sugar pyrophosphatase (EC 3.6.1.13) (8-oxo-dGDP phosphatase) (EC 3.6.1.58) (Nuclear ATP-synthesis protein NUDIX5) (EC 2.7.7.96) (Nucleoside diphosphate-linked moiety X motif 5) (Nudix motif 5) (hNUDT5) (YSA1H)

Gene: NUDT5
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9UKK9

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006338 - chromatin remodeling
GO:0006753 - nucleoside phosphate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1461122

NUDT5
ADP-sugar pyrophosphatase

2

1

High-throughput

0.783

High

1385539

P5CR2
Pyrroline-5-carboxylate reductase 2

3

1

High-throughput

0.667

High

862536

YAP1
Transcriptional coactivator YAP1

3

2

Small-scale

0.640

High

1054242

PUR1
Amidophosphoribosyltransferase

3

0

High-throughput

0.634

High

352739

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.622

High

734028

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

3

1

High-throughput

0.609

High

1439005

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

0

High-throughput

0.559

High

278177

FLNB
Filamin-B

1

2

High-throughput

0.536

High

637781

FLNA
Filamin-A

1

2

High-throughput

0.536

High

1125420

FLNC
Filamin-C

1

2

High-throughput

0.536

High

245753

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.518

High

1099815

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1137574

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.513

High

1150500

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

0

High-throughput

0.513

High

1161748

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.513

High

1217066

CBPC2
Cytosolic carboxypeptidase 2

1

0

High-throughput

0.513

High

1384518

SKA1
SKA complex subunit 1

1

0

High-throughput

0.513

High

1161256

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

380183

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.479

High

1429009

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

346476

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

412784

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

556410

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

558479

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

589999

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

607206

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

659632

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

696827

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

718657

CDC27
Cell division cycle protein 27 homolog

1

0

Small-scale

0.458

High

765104

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

831626

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

941298

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

971269

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

981172

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1033304

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1122581

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1156619

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.458

High

1233563

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1276944

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1289705

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1311989

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

1350496

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

1364670

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1459027

TRM7
tRNA

1

0

High-throughput

0.458

High

1459259

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1461123

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

1461124

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

409533

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

1410929

HSPB9
Heat shock protein beta-9

1

0

Small-scale

0.438

High

404948

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1227676

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

528528

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

0

High-throughput

0.316

High

1436717

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

51335

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

326795

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

1256673

CC062
Uncharacterized protein C3orf62

1

0

High-throughput

0.279

Low

1328597

RFLB
Refilin-B

1

0

High-throughput

0.279

Low

106826

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

377232

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

643129

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

1256034

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1420758

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025