HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	11564863, 21987584
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0045722 - positive regulation of gluconeogenesis
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 837
+	Hs
		1073090 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		KAT2A_HUMAN (75-837): 0: 1159: 100.00
+	Mm
		1265717 SF3B3_MOUSE (3-1126): 0: 1100: 21.33		KAT2A_MOUSE (1-837): 0: 1161: 97.14
+	Hs
		1073091 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		KAT2B_HUMAN (84-837): 0: 1095: 74.31
+	Hs
		998768 DDB1_HUMAN (1-1140): 0: 1424: 100.00		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Mm
		70919 DDB1_MOUSE (1-1140): 0: 1422: 99.65		EP300_MOUSE (652-832): 1.14e-36: 151: 17.94
+	Hs
		244501 DDB1_HUMAN (1-1140): 0: 1424: 100.00		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		1082298 DDB1_HUMAN (1-1140): 0: 1424: 100.00		PHIP_HUMAN (729-831): 2.23e-15: 83.3: 21.70
+	Hs
		1082415 DDB1_HUMAN (1-1140): 0: 1424: 100.00		BRWD1_HUMAN (680-831): 1.07e-13: 77.5: 20.89
+	Mm
		1112292 DDB1_MOUSE (1-1140): 0: 1422: 99.65		BRWD1_MOUSE (680-831): 2.4e-13: 76.7: 19.62
+	Mm
		1112261 DDB1_MOUSE (1-1140): 0: 1422: 99.65		TAF1_MOUSE (733-831): 8.29e-09: 61.6: 30.30
+	Hs
		998737 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		244478 SF3B3_HUMAN (3-1126): 0: 1102: 21.33		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43
+	Hs
		998611 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		EP300_HUMAN (652-832): 2.03e-37: 154: 19.02
+	Hs
		244349 CPSF1_HUMAN (4-527): 4.39e-117: 397: 15.87		BRD4_HUMAN (657-833): 1.8e-30: 131: 21.43