HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: SALL1 (Q9NSC2)
Sal-like protein 1 (Spalt-like transcription factor 1) (Zinc finger protein 794) (Zinc finger protein SALL1) (Zinc finger protein Spalt-1) (HSal1) (Sal-1)
Gene: SALL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 34795231
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 1324
+	Hs
		997883 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SALL3_HUMAN (1-1321): 0: 666: 48.78
+	Hs
		997929 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SALL1_HUMAN (1-1324): 0: 631: 85.58
+	Hs
		1083440 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		SALL2_HUMAN (1131-1316): 4.13e-14: 79.6: 25.12
+	Mm
		1141965 RBBP7_MOUSE (1-425): 3.19e-115: 345: 99.77		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92
+	Hs
		997949 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SALL4_HUMAN (1116-1215): 6.58e-15: 82.3: 26.92
+	Mm
		1141942 RBBP4_MOUSE (1-209): 1.59e-39: 148: 12.72		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92
+	Mm
		903671 WDR5_MOUSE (311-425): 1.28e-17: 85.2: 22.61		SALL4_MOUSE (1116-1215): 5.25e-14: 79.2: 26.92