Protein: KLF10
Krueppel-like factor 10 (EGR-alpha) (Transforming growth factor-beta-inducible early growth response protein 1) (TGFB-inducible early growth response protein 1) (TIEG-1)

Gene: KLF10
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q13118

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001046 - core promoter sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

464941

SP1
Transcription factor Sp1

2

18

Small-scale

0.807

High

667819

CDK2
Cyclin-dependent kinase 2

1

2

Small-scale

0.747

High

1025333

CDK6
Cyclin-dependent kinase 6

1

4

Small-scale

0.710

High

1095085

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.656

High

1095099

Z512B
Zinc finger protein 512B

1

20

High-throughput

0.656

High

1095092

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

3

Small-scale

0.625

High

586286

ZEP1
Zinc finger protein 40

1

20

High-throughput

0.618

High

613014

EGR1
Early growth response protein 1

1

18

Small-scale

0.618

High

1095100

SIN3A
Paired amphipathic helix protein Sin3a

2

10

Small-scale

0.611

High

1095096

FBXW7
F-box/WD repeat-containing protein 7

1

9

Small-scale

0.578

High

371914

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.571

High

1095106

KDM5B
Lysine-specific demethylase 5B

1

3

Small-scale

0.561

High

279354

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

1095095

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.527

High

1095104

TENS1
Tensin-1

1

2

High-throughput

0.508

High

617690

XRCC1
DNA repair protein XRCC1

1

1

High-throughput

0.500

High

976999

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

6

High-throughput

0.500

High

915898

CRIP2
Cysteine-rich protein 2

1

0

High-throughput

0.486

High

666983

CCNE1
G1/S-specific cyclin-E1

1

3

Small-scale

0.479

High

714075

PML
Protein PML

1

20

High-throughput

0.479

High

714614

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

7

Small-scale

0.479

High

1045237

TF65
Transcription factor p65

1

16

High-throughput

0.479

High

1095082

CTBP1
C-terminal-binding protein 1

1

5

High-throughput

0.479

High

1095083

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1095086

ELAV1
ELAV-like protein 1

1

4

Small-scale

0.479

High

1095087

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1095088

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

9

High-throughput

0.479

High

1095090

I2BP2
Interferon regulatory factor 2-binding protein 2

1

4

High-throughput

0.479

High

1095091

I2BP1
Interferon regulatory factor 2-binding protein 1

1

2

High-throughput

0.479

High

1095101

SP130
Histone deacetylase complex subunit SAP130

1

9

High-throughput

0.479

High

1095102

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

5

High-throughput

0.479

High

1095103

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

9

High-throughput

0.479

High

1095105

SHCAF
SIN3-HDAC complex-associated factor

1

2

High-throughput

0.479

High

898627

RL14
Large ribosomal subunit protein eL14

1

3

High-throughput

0.464

High

1095084

BOP1
Ribosome biogenesis protein BOP1

1

5

High-throughput

0.464

High

431562

AP2A
Transcription factor AP-2-alpha

1

2

High-throughput

0.457

High

447750

TPM3
Tropomyosin alpha-3 chain

1

11

High-throughput

0.457

High

995411

TPM4
Tropomyosin alpha-4 chain

1

10

High-throughput

0.457

High

1095089

MYH14
Myosin-14

1

6

High-throughput

0.457

High

1095093

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

4

High-throughput

0.457

High

1092529

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

1

High-throughput

0.437

High

1095098

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

6

Small-scale

0.437

High

1095094

PIGC
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

1

0

High-throughput

0.265

Low

1095097

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025