HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 2514
+	Hs
		1346974 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Xl
		1093463 TB1RA_XENLA (206-415): 1.35e-33: 133: 19.76		Q1W3Z6_XENLA (4-2514): 7.45e-150: 523: 51.60
+	Xl
		1186358 TB1RA_XENLA (206-415): 1.35e-33: 133: 19.76		NCOR1_XENLA (1-2514): 7.28e-122: 434: 32.87
+	Hs
		1083357 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		1083355 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		793042 LIS1_HUMAN (8-257): 7.41e-58: 196: 12.77		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1346970 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		997958 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		SRRM2_HUMAN (11-1905): 4.06e-30: 133: 8.95
+	Hs
		1302927 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		997865 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1074805 TAF5_HUMAN (1-255): 1.65e-36: 143: 17.31		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Mm
		1206786 TBL1X_MOUSE (301-415): 8.16e-13: 72.1: 17.39		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		997967 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		CABIN_HUMAN (722-1134): 2.25e-13: 78.9: 19.17
+	Mm
		1206586 TBL1R_MOUSE (301-415): 2.3e-12: 70.6: 17.39		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		929744 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		929620 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		903450 WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		903374 WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61		KMT2C_HUMAN (679-1264): 4.24e-16: 88: 11.93