Protein: SIR1
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]

Gene: SIR1, SIRT1
Organism: Homo sapiens
Interactions: 426
UniProt ID: Q96EB6

Gene Ontology (top 5):
GO:0000012 - single strand break repair
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000720 - pyrimidine dimer repair by nucleotide-excision repair
GO:0000731 - DNA synthesis involved in DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1388691

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

13

Small-scale

0.768

High

414387

P53
Cellular tumor antigen p53

16

6

Small-scale

0.766

High

1323126

CCAR2
Cell cycle and apoptosis regulator protein 2

9

5

Small-scale

0.759

High

1388778

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

11

1

Small-scale

0.753

High

1100217

TIF1B
Transcription intermediary factor 1-beta

5

4

Small-scale

0.719

High

430224

JUN
Transcription factor Jun

5

5

Small-scale

0.714

High

997933

CSK21
Casein kinase II subunit alpha

5

8

Small-scale

0.712

High

1085604

FOXO1
Forkhead box protein O1

5

13

Small-scale

0.706

High

1292963

AROS
Active regulator of SIRT1

6

0

Small-scale

0.704

High

219744

FOXO3
Forkhead box protein O3

4

13

Small-scale

0.704

High

249301

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

6

0

Small-scale

0.700

High

1025316

CDKL1
Cyclin-dependent kinase-like 1

4

6

High-throughput

0.699

High

1102623

MTA1
Metastasis-associated protein MTA1

4

3

Small-scale

0.694

High

502090

H2AZ
Histone H2A.Z

1

10

High-throughput

0.691

High

1045628

TF65
Transcription factor p65

4

7

Small-scale

0.691

High

1067592

EP300
Histone acetyltransferase p300

4

13

Small-scale

0.691

High

685046

DNMT1
DNA

3

7

Small-scale

0.686

High

1127701

HIC1
Hypermethylated in cancer 1 protein

4

4

Small-scale

0.683

High

279451

TULP3
Tubby-related protein 3

5

0

Small-scale

0.682

High

1155650

EZH2
Histone-lysine N-methyltransferase EZH2

3

12

Small-scale

0.678

High

790082

ZEB1
Zinc finger E-box-binding homeobox 1

4

5

Small-scale

0.676

High

193067

FGF10
Fibroblast growth factor 10

3

3

High-throughput

0.667

High

478713

HXB5
Homeobox protein Hox-B5

3

10

High-throughput

0.667

High

586821

RS2
Small ribosomal subunit protein uS5

3

2

High-throughput

0.667

High

1287318

TAD2B
Transcriptional adapter 2-beta

3

5

High-throughput

0.667

High

1332692

ZBT38
Zinc finger and BTB domain-containing protein 38

3

3

High-throughput

0.667

High

1388757

CWC15
Spliceosome-associated protein CWC15 homolog

3

1

High-throughput

0.667

High

981004

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

Small-scale

0.665

High

1307295

H2A2B
Histone H2A type 2-B

1

8

Small-scale

0.665

High

1371229

KAT5
Histone acetyltransferase KAT5

3

5

Small-scale

0.664

High

1122947

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

2

7

Small-scale

0.659

High

372807

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.653

High

1370563

FGF11
Fibroblast growth factor 11

3

3

High-throughput

0.650

High

787892

SRBP1
Sterol regulatory element-binding protein 1

2

6

Small-scale

0.650

High

1369194

KAT2B
Histone acetyltransferase KAT2B

2

14

Small-scale

0.649

High

1029133

E2F1
Transcription factor E2F1

3

0

Small-scale

0.649

High

998665

H31
Histone H3.1

1

10

Small-scale

0.647

High

995191

CSK2B
Casein kinase II subunit beta

2

3

Small-scale

0.644

High

601978

ZNF8
Zinc finger protein 8

3

6

High-throughput

0.643

High

334224

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

1

Small-scale

0.641

High

1388782

IRS2
Insulin receptor substrate 2

2

9

Small-scale

0.641

High

315871

RECQ4
ATP-dependent DNA helicase Q4

3

9

Small-scale

0.640

High

1388737

ECT2
Protein ECT2

3

3

Small-scale

0.640

High

443471

CDK1
Cyclin-dependent kinase 1

2

6

Small-scale

0.639

High

908343

AK1D1
Aldo-keto reductase family 1 member D1

3

0

High-throughput

0.638

High

1232375

SFRP4
Secreted frizzled-related protein 4

3

0

High-throughput

0.638

High

487629

PARP1
Poly [ADP-ribose] polymerase 1

2

6

Small-scale

0.634

High

530205

TAU
Microtubule-associated protein tau

2

5

Small-scale

0.634

High

1388735

KAT8
Histone acetyltransferase KAT8

2

5

Small-scale

0.634

High

1193675

CERKL
Ceramide kinase-like protein

3

0

High-throughput

0.634

High

69813

ZN785
Zinc finger protein 785

2

5

High-throughput

0.628

High

171913

ZN263
Zinc finger protein 263

2

1

High-throughput

0.628

High

839338

MTOR
Serine/threonine-protein kinase mTOR

2

10

Small-scale

0.628

High

889788

CLK3
Dual specificity protein kinase CLK3

2

11

High-throughput

0.628

High

1276058

ZN550
Zinc finger protein 550

2

4

High-throughput

0.628

High

1294607

Z354C
Zinc finger protein 354C

2

2

High-throughput

0.628

High

1385010

ZN669
Zinc finger protein 669

2

3

High-throughput

0.628

High

1388738

WDR76
WD repeat-containing protein 76

2

7

High-throughput

0.628

High

1388762

APEX2
DNA-(apurinic or apyrimidinic site) endonuclease 2

2

2

High-throughput

0.628

High

278402

NCOR1
Nuclear receptor corepressor 1

2

11

Small-scale

0.624

High

1061608

FOXM1
Forkhead box protein M1

2

3

Small-scale

0.624

High

1161357

HIF1A
Hypoxia-inducible factor 1-alpha

2

10

Small-scale

0.624

High

1388740

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

6

Small-scale

0.624

High

216509

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

4

Small-scale

0.621

High

605215

TAL1
T-cell acute lymphocytic leukemia protein 1

2

5

High-throughput

0.618

High

1017103

H33
Histone H3.3

1

10

High-throughput

0.618

High

1312364

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

13

Small-scale

0.618

High

1388747

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

Small-scale

0.618

High

543588

ERR1
Steroid hormone receptor ERR1

2

15

Small-scale

0.611

High

285409

EED
Polycomb protein EED

2

4

Small-scale

0.611

High

461800

HS90A
Heat shock protein HSP 90-alpha

2

3

Small-scale

0.611

High

558324

XRCC6
X-ray repair cross-complementing protein 6

2

5

Small-scale

0.611

High

573868

CCNB1
G2/mitotic-specific cyclin-B1

2

3

Small-scale

0.611

High

1005629

PITX1
Pituitary homeobox 1

2

5

High-throughput

0.611

High

1039329

RL6
Large ribosomal subunit protein eL6

2

1

High-throughput

0.611

High

1388741

SP110
Sp110 nuclear body protein

2

12

High-throughput

0.611

High

789552

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.604

High

1322235

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.602

High

1388708

SOST
Sclerostin

2

0

High-throughput

0.602

High

1388753

TBCC1
TBCC domain-containing protein 1

2

0

High-throughput

0.602

High

634865

HXA5
Homeobox protein Hox-A5

2

9

High-throughput

0.601

High

772516

IRS1
Insulin receptor substrate 1

2

12

Small-scale

0.601

High

941037

HDAC4
Histone deacetylase 4

2

10

Small-scale

0.601

High

1368047

HDAC2
Histone deacetylase 2

2

9

Small-scale

0.601

High

1370523

FGF13
Fibroblast growth factor 13

2

3

High-throughput

0.601

High

1388695

ZMAT2
Zinc finger matrin-type protein 2

2

2

High-throughput

0.601

High

1388736

DCR1B
5' exonuclease Apollo

2

2

High-throughput

0.601

High

1154419

STK11
Serine/threonine-protein kinase STK11

2

0

Small-scale

0.598

High

186786

P73
Tumor protein p73

1

6

Small-scale

0.596

High

697215

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

Small-scale

0.596

High

728377

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.596

High

1197490

VWA3B
von Willebrand factor A domain-containing protein 3B

2

0

High-throughput

0.595

High

1246923

RICTR
Rapamycin-insensitive companion of mTOR

2

2

Small-scale

0.595

High

1111184

SNW1
SNW domain-containing protein 1

1

2

Small-scale

0.594

High

714343

PML
Protein PML

1

7

Small-scale

0.589

High

1149272

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

14

Small-scale

0.589

High

520620

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.586

High

1137448

SUZ12
Polycomb protein SUZ12

2

0

Small-scale

0.585

High

260284

BRD4
Bromodomain-containing protein 4

2

14

Small-scale

0.584

High

396685

ESR1
Estrogen receptor

2

20

Small-scale

0.584

High

447305

NPM
Nucleophosmin

2

2

Small-scale

0.584

High

834022

HNF4A
Hepatocyte nuclear factor 4-alpha

2

15

Small-scale

0.584

High

1109981

HDAC1
Histone deacetylase 1

2

9

Small-scale

0.584

High

1369149

KAT2A
Histone acetyltransferase KAT2A

2

17

Small-scale

0.584

High

262112

NBN
Nibrin

1

0

Small-scale

0.583

High

370754

FOS
Protein c-Fos

1

5

Small-scale

0.578

High

406483

MYCN
N-myc proto-oncogene protein

1

8

Small-scale

0.578

High

520274

ANDR
Androgen receptor

1

14

Small-scale

0.578

High

1124684

SRC8
Src substrate cortactin

1

2

Small-scale

0.578

High

1126802

HES1
Transcription factor HES-1

1

5

Small-scale

0.578

High

1388692

CHFR
E3 ubiquitin-protein ligase CHFR

1

1

Small-scale

0.578

High

1388730

HIPK2
Homeodomain-interacting protein kinase 2

1

17

Small-scale

0.578

High

1388761

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

5

Small-scale

0.578

High

1388763

BAZ1B
Tyrosine-protein kinase BAZ1B

1

19

Small-scale

0.578

High

1388776

FZR1
Fizzy-related protein homolog

1

8

Small-scale

0.578

High

1355985

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

Small-scale

0.578

High

879744

MAPK2
MAP kinase-activated protein kinase 2

2

0

High-throughput

0.576

High

1023595

CYC
Cytochrome c

2

0

High-throughput

0.576

High

1331834

SYT2
Synaptotagmin-2

2

0

High-throughput

0.576

High

1388759

DNM3B
DNA

2

0

Small-scale

0.576

High

1047852

TLE1
Transducin-like enhancer protein 1

1

2

Small-scale

0.573

High

1156178

ZYX
Zyxin

1

2

Small-scale

0.573

High

1388739

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

Small-scale

0.564

High

132756

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

13

Small-scale

0.561

High

177703

SMAD7
Mothers against decapentaplegic homolog 7

1

1

Small-scale

0.561

High

192952

CLOCK
Circadian locomoter output cycles protein kaput

1

10

Small-scale

0.561

High

409031

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

Small-scale

0.561

High

543527

VDR
Vitamin D3 receptor

1

18

Small-scale

0.561

High

604848

HXB9
Homeobox protein Hox-B9

1

8

Small-scale

0.561

High

635210

HNF1A
Hepatocyte nuclear factor 1-alpha

1

1

Small-scale

0.561

High

667977

CDK2
Cyclin-dependent kinase 2

1

6

Small-scale

0.561

High

696185

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

Small-scale

0.561

High

853724

MK08
Mitogen-activated protein kinase 8

1

4

Small-scale

0.561

High

960520

PSME3
Proteasome activator complex subunit 3

1

1

Small-scale

0.561

High

1028334

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

Small-scale

0.561

High

1060624

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.561

High

1115355

CUL4B
Cullin-4B

1

5

Small-scale

0.561

High

1157862

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.561

High

1388701

MPP8
M-phase phosphoprotein 8

1

9

Small-scale

0.561

High

1388703

NECD
Necdin

1

3

Small-scale

0.561

High

1388706

EPAS1
Endothelial PAS domain-containing protein 1

1

8

Small-scale

0.561

High

1388707

ANM1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.561

High

1388718

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

5

Small-scale

0.561

High

1388726

BC11A
BCL11 transcription factor A

1

5

Small-scale

0.561

High

1388760

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

1

Small-scale

0.561

High

827888

STAT3
Signal transducer and activator of transcription 3

2

0

Small-scale

0.559

High

1352680

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

2

0

Small-scale

0.559

High

1023215

FOXO4
Forkhead box protein O4

1

12

Small-scale

0.554

High

1388700

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.554

High

1025405

CDK6
Cyclin-dependent kinase 6

1

7

Small-scale

0.550

High

442788

RB
Retinoblastoma-associated protein

2

0

Small-scale

0.547

High

1094236

ACACA
Acetyl-CoA carboxylase 1

1

16

Small-scale

0.546

High

390257

FETA
Alpha-fetoprotein

1

0

Small-scale

0.537

High

1032770

SATB1
DNA-binding protein SATB1

1

0

Small-scale

0.537

High

1289033

CATAC
Centrosomal AT-AC splicing factor

1

0

Small-scale

0.537

High

1388698

NR1H4
Bile acid receptor

1

20

Small-scale

0.536

High

49573

FEZF1
Fez family zinc finger protein 1

1

3

High-throughput

0.536

High

212304

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

5

Small-scale

0.536

High

625555

CSK22
Casein kinase II subunit alpha'

1

11

Small-scale

0.536

High

749101

RL9
Large ribosomal subunit protein uL6

1

2

High-throughput

0.536

High

841870

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.536

High

961204

FGF12
Fibroblast growth factor 12

1

3

High-throughput

0.536

High

975857

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.536

High

1052898

HME1
Homeobox protein engrailed-1

1

8

High-throughput

0.536

High

1088501

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

11

Small-scale

0.536

High

1128664

ZN460
Zinc finger protein 460

1

2

High-throughput

0.536

High

1181527

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

4

High-throughput

0.536

High

1234608

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

2

High-throughput

0.536

High

1322619

RPTOR
Regulatory-associated protein of mTOR

1

5

Small-scale

0.536

High

1323266

SIX5
Homeobox protein SIX5

1

3

High-throughput

0.536

High

1350641

ZN675
Zinc finger protein 675

1

1

High-throughput

0.536

High

1356127

THAP3
THAP domain-containing protein 3

1

1

High-throughput

0.536

High

1361083

MYO3B
Myosin-IIIb

1

7

High-throughput

0.536

High

1385456

ZN707
Zinc finger protein 707

1

4

High-throughput

0.536

High

1388693

ZN514
Zinc finger protein 514

1

4

High-throughput

0.536

High

1388711

NOC4L
Nucleolar complex protein 4 homolog

1

5

Small-scale

0.536

High

1388744

AGO4
Protein argonaute-4

1

2

High-throughput

0.536

High

1388756

DDX56
Probable ATP-dependent RNA helicase DDX56

1

9

High-throughput

0.536

High

1388774

ZN777
Zinc finger protein 777

1

3

High-throughput

0.536

High

159390

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

7

Small-scale

0.534

High

208335

RRP8
Ribosomal RNA-processing protein 8

1

2

Small-scale

0.534

High

654126

XPA
DNA repair protein complementing XP-A cells

1

0

Small-scale

0.530

High

138743

IMA4
Importin subunit alpha-4

1

7

Small-scale

0.515

High

138936

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

13

Small-scale

0.515

High

159794

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

6

Small-scale

0.515

High

532853

CH60
60 kDa heat shock protein, mitochondrial

1

5

Small-scale

0.515

High

535401

BIP
Endoplasmic reticulum chaperone BiP

1

10

Small-scale

0.515

High

688102

EF1G
Elongation factor 1-gamma

1

1

Small-scale

0.515

High

699828

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

2

Small-scale

0.515

High

713125

NOS3
Nitric oxide synthase 3

1

1

Small-scale

0.515

High

749489

C2TA
MHC class II transactivator

1

3

Small-scale

0.515

High

761482

HS71L
Heat shock 70 kDa protein 1-like

1

6

Small-scale

0.515

High

764959

CTNB1
Catenin beta-1

1

11

Small-scale

0.515

High

911047

IMA1
Importin subunit alpha-1

1

7

Small-scale

0.515

High

1040888

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

Small-scale

0.515

High

1124010

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

Small-scale

0.515

High

1152582

ELAV1
ELAV-like protein 1

1

4

Small-scale

0.515

High

1295384

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

1

3

Small-scale

0.515

High

1371400

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

6

Small-scale

0.515

High

1388721

NAT10
RNA cytidine acetyltransferase

1

2

Small-scale

0.515

High

1388729

ATG5
Autophagy protein 5

1

1

Small-scale

0.515

High

1388742

ELL3
RNA polymerase II elongation factor ELL3

1

2

Small-scale

0.515

High

1388783

HES2
Transcription factor HES-2

1

7

Small-scale

0.515

High

709217

IMPA1
Inositol monophosphatase 1

1

0

High-throughput

0.513

High

877783

TNNI2
Troponin I, fast skeletal muscle

1

0

High-throughput

0.513

High

1053160

STP2
Nuclear transition protein 2

1

0

High-throughput

0.513

High

1117201

THOC5
THO complex subunit 5

1

0

High-throughput

0.513

High

1388733

RPP21
Ribonuclease P protein subunit p21

1

0

High-throughput

0.513

High

1388764

TRM6
tRNA

1

0

High-throughput

0.513

High

1388779

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1388781

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

1041579

KMT2A
Histone-lysine N-methyltransferase 2A

1

10

Small-scale

0.506

High

993703

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.501

High

1060282

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

2

Small-scale

0.501

High

1093158

STK4
Serine/threonine-protein kinase 4

1

6

Small-scale

0.501

High

1388717

BHE41
Class E basic helix-loop-helix protein 41

1

7

Small-scale

0.501

High

913853

ZN138
Zinc finger protein 138

1

2

High-throughput

0.500

High

1252439

ZN793
Zinc finger protein 793

1

3

High-throughput

0.500

High

890873

TSC2
Tuberin

1

0

Small-scale

0.493

High

994713

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.493

High

1119250

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

Small-scale

0.493

High

1198139

RHG29
Rho GTPase-activating protein 29

1

0

Small-scale

0.493

High

1242122

MTFR2
Mitochondrial fission regulator 2

1

0

High-throughput

0.493

High

1388748

ZHANG
CREB/ATF bZIP transcription factor

1

0

Small-scale

0.493

High

1388750

DIAP3
Protein diaphanous homolog 3

1

0

Small-scale

0.493

High

1388787

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

Small-scale

0.493

High

1251340

DJC14
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.489

High

964413

SUMO2
Small ubiquitin-related modifier 2

1

0

Small-scale

0.480

High

1154901

NEDD8
Ubiquitin-like protein NEDD8

1

0

Small-scale

0.480

High

1388713

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.480

High

58743

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

4

High-throughput

0.479

High

122540

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

3

High-throughput

0.479

High

132223

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

Small-scale

0.479

High

143184

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

227176

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

12

Small-scale

0.479

High

228339

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

1

Small-scale

0.479

High

228503

LANC1
Glutathione S-transferase LANCL1

1

1

Small-scale

0.479

High

242554

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

250762

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

4

Small-scale

0.479

High

253675

IMA7
Importin subunit alpha-7

1

7

High-throughput

0.479

High

253782

UGDH
UDP-glucose 6-dehydrogenase

1

2

Small-scale

0.479

High

298425

DNJC8
DnaJ homolog subfamily C member 8

1

5

High-throughput

0.479

High

298947

DNJB5
DnaJ homolog subfamily B member 5

1

1

High-throughput

0.479

High

316943

MTA2
Metastasis-associated protein MTA2

1

3

Small-scale

0.479

High

334575

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

9

Small-scale

0.479

High

337383

PARN
Poly(A)-specific ribonuclease PARN

1

1

High-throughput

0.479

High

342287

BRD1
Bromodomain-containing protein 1

1

4

High-throughput

0.479

High

343005

HERC2
E3 ubiquitin-protein ligase HERC2

1

11

Small-scale

0.479

High

355017

CHK2
Serine/threonine-protein kinase Chk2

1

6

Small-scale

0.479

High

386075

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

Small-scale

0.479

High

474201

NFIC
Nuclear factor 1 C-type

1

6

High-throughput

0.479

High

481357

HMGB1
High mobility group protein B1

1

6

Small-scale

0.479

High

482163

RET1
Retinol-binding protein 1

1

1

Small-scale

0.479

High

598174

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

Small-scale

0.479

High

605091

JUND
Transcription factor JunD

1

4

Small-scale

0.479

High

648834

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

1

Small-scale

0.479

High

658751

JAK1
Tyrosine-protein kinase JAK1

1

1

Small-scale

0.479

High

708863

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

2

High-throughput

0.479

High

716603

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

2

Small-scale

0.479

High

761815

HSP74
Heat shock 70 kDa protein 4

1

13

Small-scale

0.479

High

765783

BMI1
Polycomb complex protein BMI-1

1

3

Small-scale

0.479

High

800037

COIL
Coilin

1

1

High-throughput

0.479

High

801456

HSPA9
Stress-70 protein, mitochondrial

1

14

Small-scale

0.479

High

832765

BCL6
B-cell lymphoma 6 protein

1

5

Small-scale

0.479

High

839913

AF9
Protein AF-9

1

4

Small-scale

0.479

High

862364

YAP1
Transcriptional coactivator YAP1

1

7

Small-scale

0.479

High

887107

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

899763

PAPOA
Poly(A) polymerase alpha

1

1

Small-scale

0.479

High

905460

HCFC1
Host cell factor 1

1

4

Small-scale

0.479

High

933952

NR1H2
Oxysterols receptor LXR-beta

1

20

Small-scale

0.479

High

945721

FOXL2
Forkhead box protein L2

1

3

Small-scale

0.479

High

957812

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

Small-scale

0.479

High

965822

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

7

Small-scale

0.479

High

1004383

NOP14
Nucleolar protein 14

1

1

Small-scale

0.479

High

1024753

VIGLN
Vigilin

1

6

High-throughput

0.479

High

1026504

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.479

High

1030027

RELB
Transcription factor RelB

1

7

Small-scale

0.479

High

1033135

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

1037918

HEN2
Helix-loop-helix protein 2

1

5

Small-scale

0.479

High

1040748

ENL
Protein ENL

1

8

Small-scale

0.479

High

1066437

RBBP4
Histone-binding protein RBBP4

1

6

Small-scale

0.479

High

1087937

NFIA
Nuclear factor 1 A-type

1

6

High-throughput

0.479

High

1095509

NR1H3
Oxysterols receptor LXR-alpha

1

20

Small-scale

0.479

High

1097478

CBX3
Chromobox protein homolog 3

1

6

High-throughput

0.479

High

1101469

KCAB2
Voltage-gated potassium channel subunit beta-2

1

1

Small-scale

0.479

High

1113956

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1114995

CUL4A
Cullin-4A

1

5

Small-scale

0.479

High

1115899

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

15

Small-scale

0.479

High

1123077

FHL2
Four and a half LIM domains protein 2

1

1

Small-scale

0.479

High

1133596

NFIX
Nuclear factor 1 X-type

1

7

High-throughput

0.479

High

1140128

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

Small-scale

0.479

High

1158955

RBBP7
Histone-binding protein RBBP7

1

7

Small-scale

0.479

High

1159799

OCLN
Occludin

1

2

High-throughput

0.479

High

1161875

DUS5
Dual specificity protein phosphatase 5

1

1

High-throughput

0.479

High

1195580

ARI4B
AT-rich interactive domain-containing protein 4B

1

8

Small-scale

0.479

High

1219872

OBI1
ORC ubiquitin ligase 1

1

1

Small-scale

0.479

High

1220474

K2C79
Keratin, type II cytoskeletal 79

1

3

Small-scale

0.479

High

1232364

Q6FHH6
Glutathione S-transferase LANCL1

1

1

Small-scale

0.479

High

1237913

PHLB3
Pleckstrin homology-like domain family B member 3

1

6

Small-scale

0.479

High

1241282

TAF2
Transcription initiation factor TFIID subunit 2

1

2

Small-scale

0.479

High

1255013

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1258021

UBP31
Ubiquitin carboxyl-terminal hydrolase 31

1

6

Small-scale

0.479

High

1287003

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

8

Small-scale

0.479

High

1287239

Q86TH3
Dishevelled, dsh homolog 1

1

4

Small-scale

0.479

High

1287406

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

Small-scale

0.479

High

1314356

SLX4
Structure-specific endonuclease subunit SLX4

1

7

High-throughput

0.479

High

1325226

CMYA5
Cardiomyopathy-associated protein 5

1

7

Small-scale

0.479

High

1334756

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1340777

COP1
E3 ubiquitin-protein ligase COP1

1

8

Small-scale

0.479

High

1361206

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

1364204

TOPB1
DNA topoisomerase 2-binding protein 1

1

4

Small-scale

0.479

High

1368559

KAT6A
Histone acetyltransferase KAT6A

1

14

High-throughput

0.479

High

1371590

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

13

Small-scale

0.479

High

1380074

FBXW7
F-box/WD repeat-containing protein 7

1

6

Small-scale

0.479

High

1381571

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

9

High-throughput

0.479

High

1388621

SPDLY
Protein Spindly

1

5

Small-scale

0.479

High

1388699

TRIB3
Tribbles homolog 3

1

4

Small-scale

0.479

High

1388702

POP1
Ribonucleases P/MRP protein subunit POP1

1

2

High-throughput

0.479

High

1388704

PITX2
Pituitary homeobox 2

1

5

High-throughput

0.479

High

1388714

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

7

High-throughput

0.479

High

1388715

FOXP3
Forkhead box protein P3

1

7

Small-scale

0.479

High

1388719

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.479

High

1388720

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

1388722

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

6

Small-scale

0.479

High

1388723

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

5

Small-scale

0.479

High

1388724

TSYL1
Testis-specific Y-encoded-like protein 1

1

3

Small-scale

0.479

High

1388725

ING2
Inhibitor of growth protein 2

1

8

Small-scale

0.479

High

1388727

DUS15
Dual specificity protein phosphatase 15

1

1

High-throughput

0.479

High

1388732

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

5

Small-scale

0.479

High

1388743

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

6

Small-scale

0.479

High

1388752

DJC17
DnaJ homolog subfamily C member 17

1

10

High-throughput

0.479

High

1388754

WDR70
WD repeat-containing protein 70

1

2

Small-scale

0.479

High

1388765

ANC2
Anaphase-promoting complex subunit 2

1

7

Small-scale

0.479

High

1388766

ING1
Inhibitor of growth protein 1

1

8

Small-scale

0.479

High

1388767

DJC12
DnaJ homolog subfamily C member 12

1

5

High-throughput

0.479

High

1388769

AGO2
Protein argonaute-2

1

2

High-throughput

0.479

High

1388770

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.479

High

1388772

ZN346
Zinc finger protein 346

1

2

Small-scale

0.479

High

1388775

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

2

Small-scale

0.479

High

1388785

MAFB
Transcription factor MafB

1

4

High-throughput

0.479

High

1388786

HCFC2
Host cell factor 2

1

4

Small-scale

0.479

High

282288

SAP30
Histone deacetylase complex subunit SAP30

1

0

Small-scale

0.458

High

319166

ST65G
STAGA complex 65 subunit gamma

1

0

Small-scale

0.458

High

352219

MBD3
Methyl-CpG-binding domain protein 3

1

0

Small-scale

0.458

High

378163

TNFA
Tumor necrosis factor

1

0

Small-scale

0.458

High

555414

SKI
Ski oncogene

1

0

Small-scale

0.458

High

593185

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

617723

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

719360

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

732668

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.458

High

822809

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

844268

MTHR
Methylenetetrahydrofolate reductase

1

0

High-throughput

0.458

High

874843

SPB4
Serpin B4

1

0

Small-scale

0.458

High

982119

RAP1A
Ras-related protein Rap-1A

1

0

Small-scale

0.458

High

983929

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

1025942

NDP
Norrin

1

0

Small-scale

0.458

High

1107592

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

Small-scale

0.458

High

1110952

ITPK1
Inositol-tetrakisphosphate 1-kinase

1

0

Small-scale

0.458

High

1135635

AT7L3
Ataxin-7-like protein 3

1

0

Small-scale

0.458

High

1135773

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1180880

UVSSA
UV-stimulated scaffold protein A

1

0

Small-scale

0.458

High

1199884

AKIR2
Akirin-2

1

0

Small-scale

0.458

High

1238985

R13P3
Putative ribosomal protein uL13-like

1

0

High-throughput

0.458

High

1309734

MFN1
Mitofusin-1

1

0

Small-scale

0.458

High

1357512

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1363938

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1383971

ARK2N
Protein ARK2N

1

0

High-throughput

0.458

High

1384844

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1388696

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1388697

PUS7
Pseudouridylate synthase 7 homolog

1

0

Small-scale

0.458

High

1388705

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

Small-scale

0.458

High

1388712

SCNM1
Sodium channel modifier 1

1

0

Small-scale

0.458

High

1388716

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1388731

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.458

High

1388734

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1388745

AKIP1
A-kinase-interacting protein 1

1

0

Small-scale

0.458

High

1388749

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.458

High

1388755

BCD1
Box C/D snoRNA protein 1

1

0

Small-scale

0.458

High

1388768

TNIK
TRAF2 and NCK-interacting protein kinase

1

2

High-throughput

0.457

High

60197

ZN320
Zinc finger protein 320

1

5

High-throughput

0.445

High

76477

ZN736
Zinc finger protein 736

1

2

High-throughput

0.445

High

478298

HXD4
Homeobox protein Hox-D4

1

8

High-throughput

0.445

High

584129

FOSL2
Fos-related antigen 2

1

2

High-throughput

0.445

High

600112

ZNF20
Zinc finger protein 20

1

2

High-throughput

0.445

High

626327

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

13

Small-scale

0.445

High

686637

ELAV4
ELAV-like protein 4

1

4

High-throughput

0.445

High

892916

MRE11
Double-strand break repair protein MRE11

1

2

Small-scale

0.445

High

1036613

ZNF45
Zinc finger protein 45

1

1

High-throughput

0.445

High

1241435

ZFP1
Zinc finger protein 1 homolog

1

1

High-throughput

0.445

High

1271968

ZN765
Zinc finger protein 765

1

5

High-throughput

0.445

High

1273081

ZN627
Zinc finger protein 627

1

3

High-throughput

0.445

High

1290466

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

7

High-throughput

0.445

High

1327411

ZN561
Zinc finger protein 561

1

2

High-throughput

0.445

High

1330809

ZN611
Zinc finger protein 611

1

4

High-throughput

0.445

High

1330872

ZN614
Zinc finger protein 614

1

1

High-throughput

0.445

High

1365810

ZN516
Zinc finger protein 516

1

4

Small-scale

0.445

High

1369737

RAD50
DNA repair protein RAD50

1

10

Small-scale

0.445

High

1388709

ZNF2
Zinc finger protein 2

1

1

High-throughput

0.445

High

1388710

ZN577
Zinc finger protein 577

1

3

High-throughput

0.445

High

1388751

ZFP57
Zinc finger protein 57 homolog

1

3

High-throughput

0.445

High

1388771

AGO1
Protein argonaute-1

1

2

High-throughput

0.445

High

1388773

ZN215
Zinc finger protein 215

1

4

High-throughput

0.445

High

1388780

RT18C
Small ribosomal subunit protein bS18m

1

3

High-throughput

0.445

High

648790

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

1

Small-scale

0.437

High

1206514

PRC2B
Protein PRRC2B

1

10

High-throughput

0.437

High

1323386

Q8N1C8
Stress-70 protein, mitochondrial

1

14

Small-scale

0.437

High

1327124

FBXL6
F-box/LRR-repeat protein 6

1

6

High-throughput

0.437

High

1359384

DNJB3
DnaJ homolog subfamily B member 3

1

4

High-throughput

0.437

High

1388728

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1388746

Q9NQ82
Uridine diphospho-glucose dehydrogenase

1

2

Small-scale

0.437

High

1388758

SEP10
Septin-10

1

1

High-throughput

0.437

High

67030

ZN729
Zinc finger protein 729

1

0

High-throughput

0.426

High

342453

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.426

High

480262

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.426

High

503640

TFPT
TCF3 fusion partner

1

0

High-throughput

0.426

High

1334351

IN80E
INO80 complex subunit E

1

0

High-throughput

0.426

High

1381441

ZN566
Zinc finger protein 566

1

0

High-throughput

0.426

High

1388777

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.426

High

1388694

MF14A
Hippocampus abundant transcript 1 protein

1

1

High-throughput

0.407

High

1103785

PLD1
Phospholipase D1

2

0

High-throughput

0.318

High

1388784

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.302

High

1163333

LAMA3
Laminin subunit alpha-3

1

0

Small-scale

0.269

Low

167461

WNT9A
Protein Wnt-9a

1

0

High-throughput

0.232

Low

516116

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low

1331418

MB213
Protein mab-21-like 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025