HitPredict

Interactor 1: C3AR (Q16581)
C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
Gene: C3AR1

Interactor 2: S39A1 (Q9NY26)
Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zinc-iron-regulated transporter-like) (Zrt- and Irt-like protein 1) (ZIP-1) (hZIP1)
Gene: SLC39A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 324
+	Rn
		78156 DRD2_RAT (5-452): 1.56e-70: 232: 16.89		B5DEF5_RAT (1-324): 9.34e-83: 255: 94.14
+	Mm
		897206 DRD2_MOUSE (5-452): 1.59e-70: 232: 16.89		S39A1_MOUSE (1-324): 3.36e-82: 253: 93.83
+	Rn
		88633 DRD2_RAT (5-452): 1.56e-70: 232: 16.89		D3ZIN1_RAT (28-321): 8.63e-58: 190: 33.01
+	Rn
		897207 DRD2_RAT (5-452): 1.56e-70: 232: 16.89		S39A3_RAT (27-323): 1.86e-57: 189: 33.65
+	Hs
		626601 FPR2_HUMAN (316-472): 7.93e-40: 148: 30.91		S39A1_HUMAN (1-324): 7.57e-82: 252: 100.00
+	Hs
		600854 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		S39A1_HUMAN (1-324): 7.57e-82: 252: 100.00
+	Hs
		1299121 GP101_HUMAN (4-472): 3.34e-53: 188: 14.06		S39A9_HUMAN (38-321): 4.08e-43: 152: 16.89
+	Hs
		600857 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		S39AA_HUMAN (135-323): 2.3e-48: 174: 19.02
+	Hs
		723086 OPRM_HUMAN (289-480): 1.16e-26: 113: 22.61		S39AD_HUMAN (31-322): 1.93e-57: 191: 19.41
+	Hs
		600778 C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60		S39A4_HUMAN (16-323): 1.13e-40: 152: 16.33
+	Hs
		1030972 GPR17_HUMAN (337-450): 2.07e-17: 85.4: 23.33		S39A4_HUMAN (16-323): 1.13e-40: 152: 16.33