Protein: DHYS
Deoxyhypusine synthase (DHS) (EC 2.5.1.46)

Gene: DHYS, DHPS
Organism: Homo sapiens
Interactions: 81
UniProt ID: P49366

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006412 - translation
GO:0008216 - spermidine metabolic process
GO:0008284 - positive regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826500

DHYS
Deoxyhypusine synthase

3

3

High-throughput

0.861

High

647513

MK03
Mitogen-activated protein kinase 3

10

3

High-throughput

0.756

High

826550

IF5A2
Eukaryotic translation initiation factor 5A-2

5

7

High-throughput

0.726

High

701990

RL9
Large ribosomal subunit protein uL6

6

0

High-throughput

0.710

High

658849

MK01
Mitogen-activated protein kinase 1

5

3

High-throughput

0.703

High

826509

IF5A1
Eukaryotic translation initiation factor 5A-1

3

7

High-throughput

0.675

High

826513

REL
Proto-oncogene c-Rel

3

0

High-throughput

0.646

High

826505

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

3

0

High-throughput

0.638

High

826516

BYST
Bystin

3

0

High-throughput

0.638

High

826529

NUD18
8-oxo-dGDP phosphatase NUDT18

2

0

High-throughput

0.613

High

826549

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.613

High

203570

KCAB3
Voltage-gated potassium channel subunit beta-3

2

1

High-throughput

0.611

High

719328

PTN7
Tyrosine-protein phosphatase non-receptor type 7

2

2

High-throughput

0.611

High

826510

CDK17
Cyclin-dependent kinase 17

2

1

High-throughput

0.611

High

826519

PTPRR
Receptor-type tyrosine-protein phosphatase R

2

1

High-throughput

0.611

High

613373

SFPQ
Splicing factor, proline- and glutamine-rich

2

0

High-throughput

0.602

High

826517

SAFB2
Scaffold attachment factor B2

2

0

High-throughput

0.602

High

826521

RHG15
Rho GTPase-activating protein 15

2

0

High-throughput

0.585

High

826555

SPHK1
Sphingosine kinase 1

2

0

High-throughput

0.585

High

450560

RET1
Retinol-binding protein 1

2

0

High-throughput

0.580

High

641340

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

826540

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.580

High

749224

BRCA1
Breast cancer type 1 susceptibility protein

2

0

High-throughput

0.561

High

826531

VASH1
Tubulinyl-Tyr carboxypeptidase 1

1

0

High-throughput

0.549

High

826547

NTAQ1
Protein N-terminal glutamine amidohydrolase

1

0

High-throughput

0.549

High

826535

DAA11
Dynein axonemal assembly factor 11

1

1

High-throughput

0.536

High

183359

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

621773

PRTN3
Myeloblastin

1

0

High-throughput

0.513

High

826504

DLX1
Homeobox protein DLX-1

1

0

High-throughput

0.513

High

826511

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.513

High

826527

PADI6
Protein-arginine deiminase type-6

1

0

High-throughput

0.513

High

826533

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.513

High

826537

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

826541

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.513

High

826542

ES8L1
Epidermal growth factor receptor kinase substrate 8-like protein 1

1

0

High-throughput

0.513

High

826544

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.513

High

826508

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.493

High

826553

PTPRH
Receptor-type tyrosine-protein phosphatase H

1

0

High-throughput

0.493

High

826501

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

56517

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

1

High-throughput

0.479

High

826518

EXOS7
Exosome complex component RRP42

1

1

High-throughput

0.479

High

826520

DUS28
Dual specificity phosphatase 28

1

1

High-throughput

0.479

High

826543

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.479

High

826551

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

1

Small-scale

0.479

High

826554

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.479

High

826558

ANC2
Anaphase-promoting complex subunit 2

1

1

High-throughput

0.479

High

826525

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

294524

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

351306

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

569379

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

826503

DRG2
Developmentally-regulated GTP-binding protein 2

1

0

High-throughput

0.458

High

826506

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

826514

CUL3
Cullin-3

1

0

High-throughput

0.458

High

826515

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.458

High

826524

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.458

High

826528

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

826545

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

826557

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

826507

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.457

High

826526

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

119854

RB27B
Ras-related protein Rab-27B

3

0

High-throughput

0.352

High

826502

ZN138
Zinc finger protein 138

3

0

High-throughput

0.352

High

826523

SUSD4
Sushi domain-containing protein 4

3

0

High-throughput

0.347

High

826532

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

826548

ZN414
Zinc finger protein 414

2

0

High-throughput

0.328

High

826536

CFA46
Cilia- and flagella-associated protein 46

2

0

High-throughput

0.313

High

58360

CI170
Uncharacterized protein encoded by LINC02872

1

0

High-throughput

0.279

Low

265890

LGR5
Leucine-rich repeat-containing G-protein coupled receptor 5

1

0

High-throughput

0.279

Low

826522

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

826534

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.279

Low

826538

ZN276
Zinc finger protein 276

1

0

High-throughput

0.279

Low

826539

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

826556

NHSL3
NHS-like protein 3

1

0

High-throughput

0.279

Low

262395

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

826512

TLE3
Transducin-like enhancer protein 3

1

0

High-throughput

0.249

Low

826530

ASXL2
Putative Polycomb group protein ASXL2

1

0

High-throughput

0.249

Low

826546

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

826552

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.249

Low

826559

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.249

Low

2094

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024