Protein: MLP3C
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)

Gene: MLP3C, MAP1LC3C
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9BXW4

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315816

ATG4B
Cysteine protease ATG4B

5

20

Small-scale

0.928

High

311750

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

16

Small-scale

0.825

High

1201299

KBTB6
Kelch repeat and BTB domain-containing protein 6

2

19

Small-scale

0.792

High

1262059

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

19

Small-scale

0.792

High

1036868

SQSTM
Sequestosome-1

12

20

Small-scale

0.755

High

1315797

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

14

Small-scale

0.755

High

1025542

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

7

20

Small-scale

0.751

High

255197

ATG13
Autophagy-related protein 13

4

7

Small-scale

0.707

High

262314

ULK1
Serine/threonine-protein kinase ULK1

4

12

Small-scale

0.696

High

306302

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

14

High-throughput

0.691

High

891303

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

14

High-throughput

0.691

High

1201898

TAXB1
Tax1-binding protein 1

4

18

Small-scale

0.688

High

1315800

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

20

High-throughput

0.681

High

1255678

RBCC1
RB1-inducible coiled-coil protein 1

3

14

Small-scale

0.670

High

1056120

NBR1
Next to BRCA1 gene 1 protein

3

12

Small-scale

0.667

High

1064108

TNIP1
TNFAIP3-interacting protein 1

3

16

High-throughput

0.658

High

915495

ACTA
Actin, aortic smooth muscle

3

15

High-throughput

0.657

High

1027422

STK3
Serine/threonine-protein kinase 3

2

14

Small-scale

0.636

High

1309818

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

14

Small-scale

0.636

High

808254

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

9

Small-scale

0.629

High

1310977

ATGA1
Autophagy-related protein 101

2

5

Small-scale

0.629

High

595841

CAN3
Calpain-3

2

3

High-throughput

0.606

High

1109688

TBC25
TBC1 domain family member 25

2

20

High-throughput

0.606

High

1169304

RUFY4
RUN and FYVE domain-containing protein 4

2

19

High-throughput

0.606

High

1283551

T53I1
Tumor protein p53-inducible nuclear protein 1

2

8

High-throughput

0.606

High

1224697

WDFY3
WD repeat and FYVE domain-containing protein 3

1

20

Small-scale

0.597

High

1287366

OPTN
Optineurin

2

14

Small-scale

0.594

High

1146808

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.586

High

1246065

RHXF1
Rhox homeobox family member 1

2

0

High-throughput

0.580

High

1315811

GMEB2
Glucocorticoid modulatory element-binding protein 2

2

0

High-throughput

0.580

High

943457

TCPB
T-complex protein 1 subunit beta

1

20

Small-scale

0.561

High

1122381

WDR81
WD repeat-containing protein 81

1

18

Small-scale

0.561

High

563669

ZNF24
Zinc finger protein 24

2

3

High-throughput

0.553

High

723096

OPRM
Mu-type opioid receptor

2

4

High-throughput

0.553

High

1217896

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.553

High

1281092

TSR2
Pre-rRNA-processing protein TSR2 homolog

2

2

High-throughput

0.553

High

1037152

MTX1
Metaxin-1

2

3

Small-scale

0.543

High

882799

STX17
Syntaxin-17

1

0

Small-scale

0.537

High

850180

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.536

High

1016859

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.536

High

1243072

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

High-throughput

0.536

High

1315802

ATG5
Autophagy protein 5

1

9

High-throughput

0.536

High

1315807

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

19

High-throughput

0.536

High

49665

IRGM
Immunity-related GTPase family M protein

1

0

Small-scale

0.529

High

127362

IPO5
Importin-5

1

8

High-throughput

0.527

High

165335

TCPR2
Tectonin beta-propeller repeat-containing protein 2

1

4

High-throughput

0.527

High

1254369

NEK9
Serine/threonine-protein kinase Nek9

1

19

High-throughput

0.527

High

1262930

RASF5
Ras association domain-containing protein 5

1

13

High-throughput

0.527

High

1264070

DAAF4
Dynein axonemal assembly factor 4

1

9

High-throughput

0.527

High

1315806

RASF1
Ras association domain-containing protein 1

1

16

High-throughput

0.527

High

1315814

TBD2B
TBC1 domain family member 2B

1

20

High-throughput

0.527

High

1074225

SF3A1
Splicing factor 3A subunit 1

1

17

High-throughput

0.506

High

183333

MEFV
Pyrin

1

12

Small-scale

0.501

High

261582

NCOR1
Nuclear receptor corepressor 1

1

7

High-throughput

0.501

High

498341

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

5

High-throughput

0.501

High

585053

RO52
E3 ubiquitin-protein ligase TRIM21

1

12

Small-scale

0.501

High

868319

ATX3
Ataxin-3

1

2

Small-scale

0.501

High

965144

ANK2
Ankyrin-2

1

15

Small-scale

0.501

High

1021453

ANK3
Ankyrin-3

1

15

Small-scale

0.501

High

1023104

STK4
Serine/threonine-protein kinase 4

1

15

High-throughput

0.501

High

1023326

TRI32
E3 ubiquitin-protein ligase TRIM32

1

12

Small-scale

0.501

High

1042457

CUL3
Cullin-3

1

4

Small-scale

0.501

High

1057102

EPN4
Clathrin interactor 1

1

11

High-throughput

0.501

High

1082964

CDC37
Hsp90 co-chaperone Cdc37

1

5

High-throughput

0.501

High

1103081

ATG2A
Autophagy-related protein 2 homolog A

1

7

High-throughput

0.501

High

1140734

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.501

High

1154071

NIPBL
Nipped-B-like protein

1

20

High-throughput

0.501

High

1257108

FNIP1
Folliculin-interacting protein 1

1

5

High-throughput

0.501

High

1260389

PDC6I
Programmed cell death 6-interacting protein

1

6

High-throughput

0.501

High

1268697

FAN
Protein FAN

1

18

High-throughput

0.501

High

1315801

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

19

High-throughput

0.501

High

1315812

DP13A
DCC-interacting protein 13-alpha

1

6

High-throughput

0.501

High

259469

NIPS2
Protein NipSnap homolog 2

1

10

High-throughput

0.481

High

533726

GYS1
Glycogen [starch] synthase, muscle

1

6

High-throughput

0.479

High

573461

TCPA
T-complex protein 1 subunit alpha

1

14

Small-scale

0.479

High

606481

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

3

Small-scale

0.479

High

751810

GRP75
Stress-70 protein, mitochondrial

1

20

Small-scale

0.479

High

771025

TCPZ
T-complex protein 1 subunit zeta

1

14

Small-scale

0.479

High

826864

TCPG
T-complex protein 1 subunit gamma

1

16

Small-scale

0.479

High

876051

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

6

High-throughput

0.479

High

1068902

PCM1
Pericentriolar material 1 protein

1

4

Small-scale

0.479

High

1286001

MOAP1
Modulator of apoptosis 1

1

2

Small-scale

0.479

High

1301537

FNBP1
Formin-binding protein 1

1

3

High-throughput

0.479

High

1304596

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

6

High-throughput

0.479

High

1315805

BIRC6
Baculoviral IAP repeat-containing protein 6

1

6

Small-scale

0.479

High

1315808

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

17

Small-scale

0.479

High

1315809

ANFY1
Rabankyrin-5

1

15

High-throughput

0.479

High

1315815

RBGP1
Rab GTPase-activating protein 1

1

20

High-throughput

0.479

High

117304

PDLI1
PDZ and LIM domain protein 1

1

3

High-throughput

0.457

High

595389

LMNB1
Lamin-B1

1

20

Small-scale

0.457

High

1246288

NCOA7
Nuclear receptor coactivator 7

1

4

High-throughput

0.457

High

1253202

TBC15
TBC1 domain family member 15

1

20

High-throughput

0.457

High

1315817

SAM50
Sorting and assembly machinery component 50 homolog

1

4

Small-scale

0.457

High

1049518

SAFB2
Scaffold attachment factor B2

1

20

High-throughput

0.437

High

1315813

CCPG1
Cell cycle progression protein 1

1

6

High-throughput

0.437

High

1315798

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

6

Small-scale

0.408

High

610030

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

20

High-throughput

0.407

High

1315810

ABC3B
DNA dC->dU-editing enzyme APOBEC-3B

1

3

High-throughput

0.407

High

1315803

BICC1
Protein bicaudal C homolog 1

1

20

High-throughput

0.373

High

1315804

RESF1
Retroelement silencing factor 1

1

4

High-throughput

0.373

High

207487

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.316

High

1315799

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024