HitPredict

Interactor 1: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Interactor 2: SC22A (Q96IW7)
Vesicle-trafficking protein SEC22a (SEC22 vesicle-trafficking protein homolog A) (SEC22 vesicle-trafficking protein-like 2)
Gene: SEC22A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Hs			1 307
+	Hs
		699279 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		SC22A_HUMAN (1-307): 2.28e-138: 395: 100.00
+	Hs
		1017753 STX4_HUMAN (1-287): 1.22e-63: 203: 43.58		SC22A_HUMAN (1-307): 2.28e-138: 395: 100.00
+	Mm
		139056 STX1A_MOUSE (1-288): 3.69e-86: 261: 98.26		SC22B_MOUSE (3-200): 1.99e-64: 203: 28.64
+	Hs
		263248 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		SC22B_HUMAN (3-200): 1.99e-64: 203: 28.64
+	Hs
		263179 STX2_HUMAN (1-288): 6.6e-82: 250: 63.89		SC22B_HUMAN (3-200): 1.99e-64: 203: 28.64
+	Rn
		699183 STX1A_RAT (1-288): 3.03e-86: 261: 98.61		VAMP7_RAT (4-212): 2.08e-53: 175: 14.67
+	Hs
		850569 STX1A_HUMAN (1-288): 1.66e-84: 256: 100.00		VAMP7_HUMAN (4-212): 1.96e-52: 173: 13.33
+	Dm
		115805 STX1A_DROME (2-287): 2.6e-75: 233: 69.90		M9PGI6_DROME (3-201): 5.1e-57: 184: 23.36
+	At
		812702 SY121_ARATH (19-266): 2.64e-58: 191: 22.27		VA722_ARATH (4-187): 8.03e-73: 225: 10.66
+	At
		1378372 SY121_ARATH (19-266): 2.64e-58: 191: 22.27		VA721_ARATH (4-187): 4.19e-72: 223: 11.17
+	Dm
		1098086 STX1A_DROME (2-287): 2.6e-75: 233: 69.90		Q7JYX5_DROME (4-211): 6.54e-55: 179: 14.73
+	Hs
		263226 STX4_HUMAN (1-287): 1.22e-63: 203: 43.58		SC22B_HUMAN (3-200): 1.99e-64: 203: 28.64
+	At
		1352937 SY122_ARATH (25-266): 1.04e-53: 179: 23.20		VA721_ARATH (4-187): 4.19e-72: 223: 11.17
+	Hs
		850562 STX3_HUMAN (1-288): 2.81e-64: 205: 62.41		VAMP7_HUMAN (4-212): 1.96e-52: 173: 13.33
+	Hs
		850561 STX4_HUMAN (1-287): 1.22e-63: 203: 43.58		VAMP7_HUMAN (4-212): 1.96e-52: 173: 13.33
+	Mm
		936372 Q8BH40_MOUSE (37-288): 4.59e-58: 188: 25.49		VAMP7_MOUSE (4-212): 3.07e-53: 175: 16.00
+	Dm
		115804 STX5_DROME (2-268): 2.15e-51: 176: 16.61		M9PGI6_DROME (3-201): 5.1e-57: 184: 23.36
+	Dm
		1097995 STX5_DROME (2-268): 2.15e-51: 176: 16.61		Q7JYX5_DROME (4-211): 6.54e-55: 179: 14.73
+	Hs
		180867 STX3_HUMAN (1-288): 2.81e-64: 205: 62.41		YKT6_HUMAN (30-176): 1.35e-38: 136: 16.15
+	Hs
		180770 STX11_HUMAN (1-274): 2.87e-54: 179: 29.72		YKT6_HUMAN (30-176): 1.35e-38: 136: 16.15