Protein: HIPK3
Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1)

Gene: HIPK3
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q9H422

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

922333

LIMK2
LIM domain kinase 2

1

18

High-throughput

0.656

High

1433059

ZN107
Zinc finger protein 107

1

1

High-throughput

0.656

High

1096927

FADD
FAS-associated death domain protein

1

8

Small-scale

0.618

High

414618

P53
Cellular tumor antigen p53

2

18

Small-scale

0.606

High

578718

GLNA
Glutamine synthetase

1

3

High-throughput

0.541

High

593215

CREB1
Cyclic AMP-responsive element-binding protein 1

1

4

High-throughput

0.541

High

987937

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.541

High

993747

UBC9
SUMO-conjugating enzyme UBC9

1

12

High-throughput

0.541

High

211598

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

18

High-throughput

0.508

High

212735

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

16

High-throughput

0.508

High

318537

TOX4
TOX high mobility group box family member 4

1

17

High-throughput

0.508

High

665143

COT2
COUP transcription factor 2

1

19

High-throughput

0.508

High

732700

ARRB2
Beta-arrestin-2

1

5

High-throughput

0.508

High

1156210

ZYX
Zyxin

1

15

High-throughput

0.508

High

1278491

LIMS2
LIM and senescent cell antigen-like-containing domain protein 2

1

13

High-throughput

0.508

High

1307796

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

15

High-throughput

0.508

High

1433056

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

2

High-throughput

0.508

High

1433057

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

5

High-throughput

0.508

High

1433058

LIMD1
LIM domain-containing protein 1

1

11

High-throughput

0.508

High

186807

P73
Tumor protein p73

1

18

Small-scale

0.481

High

991428

SUMO1
Small ubiquitin-related modifier 1

1

8

Small-scale

0.481

High

1368483

CBP
CREB-binding protein

1

20

Small-scale

0.481

High

675159

TNR6
Tumor necrosis factor receptor superfamily member 6

1

6

Small-scale

0.479

High

1114287

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1185947

PCGF3
Polycomb group RING finger protein 3

1

12

High-throughput

0.479

High

388668

C1QA
Complement C1q subcomponent subunit A

1

2

High-throughput

0.464

High

1410907

GORS1
Golgi reassembly-stacking protein 1

1

6

High-throughput

0.464

High

1199694

KLH22
Kelch-like protein 22

1

5

High-throughput

0.445

High


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Last updated: 11Aug2025