HitPredict

Interactor 1: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	27934968, 34740372
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016604 - nuclear body and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 826 Hs			1 1102
+	Hs
		1273892 ARNT2_HUMAN (2-573): 2.8e-114: 365: 18.75		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1085724 HIF1A_HUMAN (1-826): 0: 741: 100.00		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		1085629 HIF1A_HUMAN (1-826): 0: 741: 100.00		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08