Protein: FOXL1
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)

Gene: FOXL1
Organism: Homo sapiens
Interactions: 197
UniProt ID: Q12952

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1091093

FOXC1
Forkhead box protein C1

1

18

High-throughput

0.618

High

1091311

FOXP4
Forkhead box protein P4

1

18

High-throughput

0.618

High

1091343

FOXP1
Forkhead box protein P1

1

19

High-throughput

0.618

High

1032749

SATB1
DNA-binding protein SATB1

2

20

High-throughput

0.611

High

1047963

TLE3
Transducin-like enhancer protein 3

2

20

High-throughput

0.611

High

1091308

ZFHX4
Zinc finger homeobox protein 4

2

4

High-throughput

0.611

High

1091312

ARI3B
AT-rich interactive domain-containing protein 3B

2

19

High-throughput

0.611

High

1091337

ARI3A
AT-rich interactive domain-containing protein 3A

2

19

High-throughput

0.611

High

1091379

SATB2
DNA-binding protein SATB2

2

20

High-throughput

0.611

High

142975

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.578

High

1091271

FOXL1
Forkhead box protein L1

1

16

High-throughput

0.575

High

1087717

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.561

High

123088

DX39A
ATP-dependent RNA helicase DDX39A

1

10

High-throughput

0.536

High

173697

BTAF1
TATA-binding protein-associated factor 172

1

20

High-throughput

0.536

High

231471

ORC4
Origin recognition complex subunit 4

1

3

High-throughput

0.536

High

243617

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.536

High

319724

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.536

High

333999

SMC2
Structural maintenance of chromosomes protein 2

1

15

High-throughput

0.536

High

404020

GCR
Glucocorticoid receptor

1

19

High-throughput

0.536

High

451503

CENPB
Major centromere autoantigen B

1

2

High-throughput

0.536

High

522819

COT1
COUP transcription factor 1

1

14

High-throughput

0.536

High

675485

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.536

High

703305

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

20

High-throughput

0.536

High

714840

EF1D
Elongation factor 1-delta

1

3

High-throughput

0.536

High

814516

FEN1
Flap endonuclease 1

1

1

High-throughput

0.536

High

854639

RAGP1
Ran GTPase-activating protein 1

1

3

High-throughput

0.536

High

858640

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

4

High-throughput

0.536

High

879028

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.536

High

890460

RBP2
E3 SUMO-protein ligase RanBP2

1

2

High-throughput

0.536

High

903012

NOVA1
RNA-binding protein Nova-1

1

17

High-throughput

0.536

High

929779

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.536

High

937232

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

13

High-throughput

0.536

High

1028126

IRF9
Interferon regulatory factor 9

1

2

High-throughput

0.536

High

1046983

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.536

High

1060437

DPOE1
DNA polymerase epsilon catalytic subunit A

1

5

High-throughput

0.536

High

1081616

HSP7E
Heat shock 70 kDa protein 14

1

5

High-throughput

0.536

High

1085739

TF3C1
General transcription factor 3C polypeptide 1

1

2

High-throughput

0.536

High

1091273

ORC2
Origin recognition complex subunit 2

1

3

High-throughput

0.536

High

1091276

UBE4A
Ubiquitin conjugation factor E4 A

1

4

High-throughput

0.536

High

1091280

SMC1A
Structural maintenance of chromosomes protein 1A

1

16

High-throughput

0.536

High

1091282

KIF22
Kinesin-like protein KIF22

1

1

High-throughput

0.536

High

1091286

CND1
Condensin complex subunit 1

1

4

High-throughput

0.536

High

1091290

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

12

High-throughput

0.536

High

1091291

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

6

High-throughput

0.536

High

1091297

RIF1
Telomere-associated protein RIF1

1

6

High-throughput

0.536

High

1091298

ECM29
Proteasome adapter and scaffold protein ECM29

1

13

High-throughput

0.536

High

1091304

NFXL1
NF-X1-type zinc finger protein NFXL1

1

8

High-throughput

0.536

High

1091310

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

20

High-throughput

0.536

High

1091317

SIX5
Homeobox protein SIX5

1

16

High-throughput

0.536

High

1091324

STAG1
Cohesin subunit SA-1

1

2

High-throughput

0.536

High

1091327

HDAC2
Histone deacetylase 2

1

14

High-throughput

0.536

High

1091329

RAD50
DNA repair protein RAD50

1

7

High-throughput

0.536

High

1091335

STRBP
Spermatid perinuclear RNA-binding protein

1

17

High-throughput

0.536

High

1091336

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.536

High

1091338

CND3
Condensin complex subunit 3

1

1

High-throughput

0.536

High

1091342

DCNL5
DCN1-like protein 5

1

1

High-throughput

0.536

High

1091344

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

20

High-throughput

0.536

High

1091354

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

10

High-throughput

0.536

High

1091355

HELLS
Lymphoid-specific helicase

1

20

High-throughput

0.536

High

1091356

SMC4
Structural maintenance of chromosomes protein 4

1

15

High-throughput

0.536

High

1091357

MDN1
Midasin

1

5

High-throughput

0.536

High

1091365

ORC3
Origin recognition complex subunit 3

1

1

High-throughput

0.536

High

1091366

HDAC6
Protein deacetylase HDAC6

1

14

High-throughput

0.536

High

1091368

PUF60
Poly(U)-binding-splicing factor PUF60

1

4

High-throughput

0.536

High

1091372

RALY
RNA-binding protein Raly

1

11

High-throughput

0.536

High

1091373

TF3C4
General transcription factor 3C polypeptide 4

1

2

High-throughput

0.536

High

1091380

PA2G4
Proliferation-associated protein 2G4

1

2

High-throughput

0.536

High

1091381

SMC3
Structural maintenance of chromosomes protein 3

1

16

High-throughput

0.536

High

1091384

NOC2L
Nucleolar complex protein 2 homolog

1

1

High-throughput

0.536

High

1091385

TF3C5
General transcription factor 3C polypeptide 5

1

3

High-throughput

0.536

High

136212

IFRD1
Interferon-related developmental regulator 1

1

0

High-throughput

0.513

High

1091296

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

0

High-throughput

0.513

High

1091299

INT3
Integrator complex subunit 3

1

0

High-throughput

0.513

High

1091314

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.513

High

473959

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.501

High

255417

SNX2
Sorting nexin-2

1

3

High-throughput

0.489

High

291088

UTP20
Small subunit processome component 20 homolog

1

1

High-throughput

0.489

High

318006

TOM70
Mitochondrial import receptor subunit TOM70

1

5

High-throughput

0.489

High

354329

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

4

High-throughput

0.489

High

359809

DYR
Dihydrofolate reductase

1

1

High-throughput

0.489

High

687794

SYVC
Valine--tRNA ligase

1

15

High-throughput

0.489

High

690241

STOM
Stomatin

1

6

High-throughput

0.489

High

834437

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

14

High-throughput

0.489

High

841170

CNDD3
Condensin-2 complex subunit D3

1

4

High-throughput

0.489

High

857093

NSF
Vesicle-fusing ATPase

1

1

High-throughput

0.489

High

881164

FAS
Fatty acid synthase

1

2

High-throughput

0.489

High

914076

HXK2
Hexokinase-2

1

6

High-throughput

0.489

High

914148

HXK3
Hexokinase-3

1

6

High-throughput

0.489

High

915951

NUP98
Nuclear pore complex protein Nup98-Nup96

1

4

High-throughput

0.489

High

921876

COPA
Coatomer subunit alpha

1

2

High-throughput

0.489

High

1041984

LMNB2
Lamin-B2

1

4

High-throughput

0.489

High

1091274

MYO9B
Unconventional myosin-IXb

1

2

High-throughput

0.489

High

1091275

CKAP5
Cytoskeleton-associated protein 5

1

9

High-throughput

0.489

High

1091278

SCRIB
Protein scribble homolog

1

4

High-throughput

0.489

High

1091279

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.489

High

1091284

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

6

High-throughput

0.489

High

1091285

CND2
Condensin complex subunit 2

1

1

High-throughput

0.489

High

1091287

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

5

High-throughput

0.489

High

1091292

MA7D1
MAP7 domain-containing protein 1

1

4

High-throughput

0.489

High

1091295

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.489

High

1091301

SYDM
Aspartate--tRNA ligase, mitochondrial

1

5

High-throughput

0.489

High

1091307

NOP9
Nucleolar protein 9

1

2

High-throughput

0.489

High

1091316

TRM2A
tRNA

1

2

High-throughput

0.489

High

1091321

G45IP
Large ribosomal subunit protein mL64

1

3

High-throughput

0.489

High

1091323

NU133
Nuclear pore complex protein Nup133

1

1

High-throughput

0.489

High

1091325

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.489

High

1091326

NU205
Nuclear pore complex protein Nup205

1

4

High-throughput

0.489

High

1091328

SYMPK
Symplekin

1

4

High-throughput

0.489

High

1091331

RM38
Large ribosomal subunit protein mL38

1

3

High-throughput

0.489

High

1091345

HEAT1
HEAT repeat-containing protein 1

1

4

High-throughput

0.489

High

1091351

RT30
Large ribosomal subunit protein mL65

1

1

High-throughput

0.489

High

1091359

NSMA3
Sphingomyelin phosphodiesterase 4

1

7

High-throughput

0.489

High

1091360

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

2

High-throughput

0.489

High

1091362

RRBP1
Ribosome-binding protein 1

1

4

High-throughput

0.489

High

1091370

HERC5
E3 ISG15--protein ligase HERC5

1

3

High-throughput

0.489

High

1091377

COG5
Conserved oligomeric Golgi complex subunit 5

1

1

High-throughput

0.489

High

1091382

DDX52
Probable ATP-dependent RNA helicase DDX52

1

4

High-throughput

0.489

High

161460

KMT2D
Histone-lysine N-methyltransferase 2D

1

10

High-throughput

0.479

High

174349

ZN609
Zinc finger protein 609

1

7

High-throughput

0.479

High

177457

ZN536
Zinc finger protein 536

1

3

High-throughput

0.479

High

188262

HDAC3
Histone deacetylase 3

1

13

High-throughput

0.479

High

194559

KDM6A
Lysine-specific demethylase 6A

1

6

High-throughput

0.479

High

245620

ZEB2
Zinc finger E-box-binding homeobox 2

1

1

High-throughput

0.479

High

261403

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

10

High-throughput

0.479

High

278326

NCOR1
Nuclear receptor corepressor 1

1

19

High-throughput

0.479

High

285896

SF3B1
Splicing factor 3B subunit 1

1

10

High-throughput

0.479

High

505554

ATX1L
Ataxin-1-like

1

2

High-throughput

0.479

High

576225

PO2F1
POU domain, class 2, transcription factor 1

1

16

High-throughput

0.479

High

586284

ZEP1
Zinc finger protein 40

1

4

High-throughput

0.479

High

766506

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

790042

ZEB1
Zinc finger E-box-binding homeobox 1

1

1

High-throughput

0.479

High

814802

CUX1
Homeobox protein cut-like 1

1

19

High-throughput

0.479

High

927265

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

992153

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.479

High

1047808

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

1048155

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

1055796

RING1
E3 ubiquitin-protein ligase RING1

1

7

High-throughput

0.479

High

1061681

TLE5
TLE family member 5

1

20

High-throughput

0.479

High

1091272

GPS2
G protein pathway suppressor 2

1

2

High-throughput

0.479

High

1091283

ARI5B
AT-rich interactive domain-containing protein 5B

1

19

High-throughput

0.479

High

1091288

ZFHX3
Zinc finger homeobox protein 3

1

4

High-throughput

0.479

High

1091289

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.479

High

1091293

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1091302

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

9

High-throughput

0.479

High

1091303

BCOR
BCL-6 corepressor

1

9

High-throughput

0.479

High

1091305

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.479

High

1091309

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1091315

YAF2
YY1-associated factor 2

1

1

High-throughput

0.479

High

1091318

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.479

High

1091319

KMT2C
Histone-lysine N-methyltransferase 2C

1

16

High-throughput

0.479

High

1091320

KDM2B
Lysine-specific demethylase 2B

1

5

High-throughput

0.479

High

1091330

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.479

High

1091332

ZN503
Zinc finger protein 503

1

3

High-throughput

0.479

High

1091334

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1091341

PCGF1
Polycomb group RING finger protein 1

1

11

High-throughput

0.479

High

1091346

ZN703
Zinc finger protein 703

1

8

High-throughput

0.479

High

1091350

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

1091353

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

1091361

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.479

High

1091364

RCOR3
REST corepressor 3

1

15

High-throughput

0.479

High

1091367

TRPS1
Zinc finger transcription factor Trps1

1

17

High-throughput

0.479

High

1091369

DACH1
Dachshund homolog 1

1

4

High-throughput

0.479

High

1091371

SIX4
Homeobox protein SIX4

1

18

High-throughput

0.479

High

1091374

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

1091375

PRR12
Proline-rich protein 12

1

16

High-throughput

0.479

High

1091376

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.479

High

1091378

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

7

High-throughput

0.479

High

1091386

NCOR2
Nuclear receptor corepressor 2

1

14

High-throughput

0.479

High

352420

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

1048487

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1091322

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.458

High

1091333

DYL2
Dynein light chain 2, cytoplasmic

1

0

High-throughput

0.458

High

1091347

YYAP1
YY1-associated protein 1

1

0

High-throughput

0.458

High

1091352

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.458

High

1091383

ZN281
Zinc finger protein 281

1

0

High-throughput

0.458

High

75951

B4DEF8
Large ribosomal subunit protein mL45

1

5

High-throughput

0.437

High

138998

BCL9
B-cell CLL/lymphoma 9 protein

1

14

High-throughput

0.437

High

227864

MYO1B
Unconventional myosin-Ib

1

1

High-throughput

0.437

High

482895

TPM1
Tropomyosin alpha-1 chain

1

1

High-throughput

0.437

High

945219

NU107
Nuclear pore complex protein Nup107

1

3

High-throughput

0.437

High

1091281

GSE1
Genetic suppressor element 1

1

1

High-throughput

0.437

High

1091294

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.437

High

1091306

MYH14
Myosin-14

1

1

High-throughput

0.437

High

1091313

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.437

High

1091349

FBSL
Fibrosin-1-like protein

1

2

High-throughput

0.437

High

839454

PI4KA
Phosphatidylinositol 4-kinase alpha

1

2

High-throughput

0.407

High

1091339

RM45
Large ribosomal subunit protein mL45

1

5

High-throughput

0.407

High

155576

NEMP1
Nuclear envelope integral membrane protein 1

1

0

High-throughput

0.279

Low

1091277

SPIDR
DNA repair-scaffolding protein

1

0

High-throughput

0.279

Low

1091300

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.279

Low

1091358

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

1091363

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.279

Low

130080

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.249

Low

698619

CALX
Calnexin

1

0

High-throughput

0.249

Low

1091340

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low

1091348

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025