Protein: FOXK1
Forkhead box protein K1 (Myocyte nuclear factor) (MNF)

Gene: FOXK1
Organism: Homo sapiens
Interactions: 212
UniProt ID: P85037

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1017517

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

2

12

High-throughput

0.811

High

1017456

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

11

6

Small-scale

0.757

High

159607

DVL2
Segment polarity protein dishevelled homolog DVL-2

6

4

Small-scale

0.729

High

729746

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.727

High

219719

FOXO3
Forkhead box protein O3

1

19

High-throughput

0.715

High

1017440

ASXL2
Putative Polycomb group protein ASXL2

5

15

Small-scale

0.714

High

1017412

GPS2
G protein pathway suppressor 2

4

2

High-throughput

0.699

High

1017443

ASXL1
Polycomb group protein ASXL1

4

6

Small-scale

0.697

High

484103

PGFRB
Platelet-derived growth factor receptor beta

4

4

High-throughput

0.697

High

354948

CHK2
Serine/threonine-protein kinase Chk2

1

10

High-throughput

0.691

High

1017401

FOXK2
Forkhead box protein K2

1

18

High-throughput

0.691

High

1017447

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

3

High-throughput

0.691

High

1017500

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

1

14

High-throughput

0.691

High

966193

1433G
14-3-3 protein gamma

4

20

High-throughput

0.691

High

1017427

RBBP7
Histone-binding protein RBBP7

4

7

High-throughput

0.691

High

571585

IRF2
Interferon regulatory factor 2

3

6

High-throughput

0.686

High

282233

SAP30
Histone deacetylase complex subunit SAP30

3

2

High-throughput

0.675

High

1017416

HDAC1
Histone deacetylase 1

3

15

High-throughput

0.675

High

244844

TRAK2
Trafficking kinesin-binding protein 2

3

4

High-throughput

0.667

High

1017476

KLDC3
Kelch domain-containing protein 3

3

5

High-throughput

0.667

High

279340

TULP3
Tubby-related protein 3

3

1

High-throughput

0.662

High

1017414

IKZF1
DNA-binding protein Ikaros

3

5

High-throughput

0.662

High

1017424

RNPS1
RNA-binding protein with serine-rich domain 1

3

3

High-throughput

0.662

High

1017496

SHCAF
SIN3-HDAC complex-associated factor

3

1

High-throughput

0.662

High

1017405

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

711758

ARI4A
AT-rich interactive domain-containing protein 4A

2

20

High-throughput

0.628

High

964579

DCAF7
DDB1- and CUL4-associated factor 7

2

8

High-throughput

0.628

High

1017402

TFAP4
Transcription factor AP-4

2

2

High-throughput

0.628

High

1017460

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

5

High-throughput

0.628

High

1017487

ING2
Inhibitor of growth protein 2

2

9

High-throughput

0.628

High

1017488

P63
Tumor protein 63

2

13

High-throughput

0.628

High

302483

RNF8
E3 ubiquitin-protein ligase RNF8

1

6

Small-scale

0.618

High

340867

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

15

High-throughput

0.618

High

585782

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

3

High-throughput

0.618

High

738966

ELF1
ETS-related transcription factor Elf-1

1

16

High-throughput

0.618

High

837034

ELK3
ETS domain-containing protein Elk-3

1

16

High-throughput

0.618

High

1017404

TF65
Transcription factor p65

1

12

High-throughput

0.618

High

1017415

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

12

High-throughput

0.618

High

1017425

ELF2
ETS-related transcription factor Elf-2

1

14

High-throughput

0.618

High

1017426

MK14
Mitogen-activated protein kinase 14

1

3

High-throughput

0.618

High

1017445

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.618

High

1017473

FEV
Protein FEV

1

15

High-throughput

0.618

High

1017474

ELF4
ETS-related transcription factor Elf-4

1

15

High-throughput

0.618

High

1017490

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.618

High

413622

P53
Cellular tumor antigen p53

2

13

High-throughput

0.611

High

1017464

ZN428
Zinc finger protein 428

3

1

High-throughput

0.604

High

211913

SPIT1
Kunitz-type protease inhibitor 1

2

3

High-throughput

0.601

High

259795

BRD4
Bromodomain-containing protein 4

2

11

High-throughput

0.584

High

872202

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

944627

KLF3
Krueppel-like factor 3

2

17

High-throughput

0.584

High

1017409

EP300
Histone acetyltransferase p300

2

20

High-throughput

0.584

High

1017400

FOXK1
Forkhead box protein K1

1

17

High-throughput

0.575

High

622584

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

2

High-throughput

0.574

High

1017467

SAHH3
Adenosylhomocysteinase 3

2

9

High-throughput

0.574

High

395909

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

549308

SRF
Serum response factor

1

2

Small-scale

0.561

High

1017455

TITIN
Titin

1

2

High-throughput

0.553

High

1017429

DDR2
Discoidin domain-containing receptor 2

2

6

High-throughput

0.543

High

158426

RFXK
DNA-binding protein RFXANK

1

7

High-throughput

0.536

High

176294

ZBT39
Zinc finger and BTB domain-containing protein 39

1

2

High-throughput

0.536

High

177199

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

6

High-throughput

0.536

High

187061

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.536

High

230006

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

9

High-throughput

0.536

High

243847

K0513
Uncharacterized protein KIAA0513

1

1

High-throughput

0.536

High

278305

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.536

High

442668

RB
Retinoblastoma-associated protein

1

9

High-throughput

0.536

High

553743

MYCL
Protein L-Myc

1

12

High-throughput

0.536

High

636837

GSTM3
Glutathione S-transferase Mu 3

1

4

High-throughput

0.536

High

659442

CRCM
Colorectal mutant cancer protein

1

4

High-throughput

0.536

High

659762

SAHH
Adenosylhomocysteinase

1

9

High-throughput

0.536

High

704939

RBL1
Retinoblastoma-like protein 1

1

9

High-throughput

0.536

High

765391

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.536

High

833591

UBA7
Ubiquitin-like modifier-activating enzyme 7

1

1

High-throughput

0.536

High

943464

DSCR6
Protein ripply3

1

1

High-throughput

0.536

High

959562

MAX
Protein max

1

12

High-throughput

0.536

High

1017408

RBL2
Retinoblastoma-like protein 2

1

9

High-throughput

0.536

High

1017411

TP53B
TP53-binding protein 1

1

6

High-throughput

0.536

High

1017417

FHL3
Four and a half LIM domains protein 3

1

5

High-throughput

0.536

High

1017420

SCRIB
Protein scribble homolog

1

5

High-throughput

0.536

High

1017421

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

1017430

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.536

High

1017431

AMOT
Angiomotin

1

13

High-throughput

0.536

High

1017432

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

8

High-throughput

0.536

High

1017433

UBR4
E3 ubiquitin-protein ligase UBR4

1

4

High-throughput

0.536

High

1017434

FAXC
Failed axon connections homolog

1

1

High-throughput

0.536

High

1017435

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

12

High-throughput

0.536

High

1017442

TF2LX
Homeobox protein TGIF2LX

1

9

High-throughput

0.536

High

1017446

CLASR
CLK4-associating serine/arginine rich protein

1

1

High-throughput

0.536

High

1017458

HDAC2
Histone deacetylase 2

1

15

High-throughput

0.536

High

1017463

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1017468

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

12

High-throughput

0.536

High

1017471

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

11

High-throughput

0.536

High

1017472

SIN3A
Paired amphipathic helix protein Sin3a

1

6

High-throughput

0.536

High

1017475

NPAS1
Neuronal PAS domain-containing protein 1

1

11

High-throughput

0.536

High

1017480

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

12

High-throughput

0.536

High

1017481

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1017486

SP130
Histone deacetylase complex subunit SAP130

1

14

High-throughput

0.536

High

1017493

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

8

High-throughput

0.536

High

1017495

BRMS1
Breast cancer metastasis-suppressor 1

1

8

High-throughput

0.536

High

1017509

ING1
Inhibitor of growth protein 1

1

10

High-throughput

0.536

High

1017512

CBPC1
Cytosolic carboxypeptidase 1

1

1

High-throughput

0.536

High

886750

CEBPA
CCAAT/enhancer-binding protein alpha

1

14

High-throughput

0.527

High

116962

J3KNN3
phosphorylase kinase

1

2

High-throughput

0.514

High

212877

AP5Z1
AP-5 complex subunit zeta-1

1

0

High-throughput

0.513

High

1017444

TM192
Transmembrane protein 192

1

0

High-throughput

0.513

High

1017502

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

951612

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.501

High

346954

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

420490

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.489

High

718385

CD6
T-cell differentiation antigen CD6

1

3

High-throughput

0.489

High

854427

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

1

High-throughput

0.489

High

1017436

BLT3A
Bridge-like lipid transfer protein family member 3A

1

1

High-throughput

0.489

High

1017437

PLBL1
Phospholipase B-like 1

1

1

High-throughput

0.489

High

1017449

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

5

High-throughput

0.489

High

1017453

NPRL2
GATOR1 complex protein NPRL2

1

1

High-throughput

0.489

High

1017466

ZB10P
Putative protein ZBED10P

1

1

High-throughput

0.489

High

1017469

CC85A
Coiled-coil domain-containing protein 85A

1

1

High-throughput

0.489

High

1017478

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

6

High-throughput

0.489

High

1017485

DNAI2
Dynein axonemal intermediate chain 2

1

14

High-throughput

0.489

High

1017491

RABE2
Rab GTPase-binding effector protein 2

1

6

High-throughput

0.489

High

1017494

TANC2
Protein TANC2

1

7

High-throughput

0.489

High

1017497

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

1

High-throughput

0.489

High

1017501

HPBP1
Hsp70-binding protein 1

1

5

High-throughput

0.489

High

1017506

FBLN5
Fibulin-5

1

9

High-throughput

0.489

High

1017513

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

3

High-throughput

0.489

High

1017515

DOP1B
Protein DOP1B

1

1

High-throughput

0.489

High

128971

MEN1
Menin

1

6

High-throughput

0.479

High

142938

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

172699

XPO1
Exportin-1

1

11

High-throughput

0.479

High

194545

KDM6A
Lysine-specific demethylase 6A

1

7

Small-scale

0.479

High

209981

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

224973

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

239936

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

339721

KLF8
Krueppel-like factor 8

1

19

High-throughput

0.479

High

406068

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

473917

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

519947

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

536970

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

606628

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

629784

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

685156

PAX6
Paired box protein Pax-6

1

16

High-throughput

0.479

High

690903

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

695215

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

697073

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

714030

PML
Protein PML

1

11

High-throughput

0.479

High

725240

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

731201

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

767960

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

776049

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

799847

COIL
Coilin

1

1

High-throughput

0.479

High

883503

CENPA
Histone H3-like centromeric protein A

1

10

High-throughput

0.479

High

895702

LHX2
LIM/homeobox protein Lhx2

1

12

High-throughput

0.479

High

905378

HCFC1
Host cell factor 1

1

5

Small-scale

0.479

High

938431

PAX9
Paired box protein Pax-9

1

12

High-throughput

0.479

High

971401

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.479

High

979500

H4
Histone H4

1

6

High-throughput

0.479

High

990094

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1016776

H33
Histone H3.3

1

10

High-throughput

0.479

High

1017403

HEN1
Helix-loop-helix protein 1

1

2

High-throughput

0.479

High

1017407

GOGA2
Golgin subfamily A member 2

1

5

High-throughput

0.479

High

1017410

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1017413

CTBP1
C-terminal-binding protein 1

1

9

High-throughput

0.479

High

1017418

KLF9
Krueppel-like factor 9

1

14

High-throughput

0.479

High

1017419

KLF5
Krueppel-like factor 5

1

17

High-throughput

0.479

High

1017422

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1017423

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1017428

TBR1
T-box brain protein 1

1

7

High-throughput

0.479

High

1017438

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1017441

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1017450

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1017451

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

1017452

SP7
Transcription factor Sp7

1

14

High-throughput

0.479

High

1017454

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

1017457

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1017459

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1017461

LHX4
LIM/homeobox protein Lhx4

1

9

High-throughput

0.479

High

1017465

MBD6
Methyl-CpG-binding domain protein 6

1

8

High-throughput

0.479

High

1017470

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1017479

MET22
Methyltransferase-like protein 22

1

2

High-throughput

0.479

High

1017482

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1017492

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1017499

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

2

High-throughput

0.479

High

1017503

MBD5
Methyl-CpG-binding domain protein 5

1

2

High-throughput

0.479

High

1017504

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

11

High-throughput

0.479

High

1017505

LHX3
LIM/homeobox protein Lhx3

1

7

High-throughput

0.479

High

1017507

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1017508

KLF15
Krueppel-like factor 15

1

17

High-throughput

0.479

High

1017510

BAG5
BAG family molecular chaperone regulator 5

1

2

High-throughput

0.479

High

1017511

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

8

High-throughput

0.479

High

1017516

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1017518

KLF12
Krueppel-like factor 12

1

17

High-throughput

0.479

High

1017519

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

High-throughput

0.479

High

293561

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

1017520

TX264
Testis-expressed protein 264

1

0

High-throughput

0.458

High

166516

BACH1
Transcription regulator protein BACH1

1

12

High-throughput

0.445

High

848771

MAGAA
Melanoma-associated antigen 10

1

4

High-throughput

0.445

High

1017439

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.445

High

1017448

STAG2
Cohesin subunit SA-2

1

2

Small-scale

0.445

High

105758

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

411740

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

1017406

DDR1
Epithelial discoidin domain-containing receptor 1

1

4

High-throughput

0.437

High

1017483

ASXL3
Putative Polycomb group protein ASXL3

1

11

Small-scale

0.437

High

1017498

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

1017514

NINL
Ninein-like protein

1

6

High-throughput

0.437

High

1017462

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.426

High

64174

ARG35
Rho guanine nucleotide exchange factor 35

1

1

High-throughput

0.407

High

1017477

GORS1
Golgi reassembly-stacking protein 1

1

2

High-throughput

0.407

High

1017484

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

4

High-throughput

0.407

High

1017489

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

4

High-throughput

0.407

High

921530

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

0

High-throughput

0.347

High

247107

TBCD4
TBC1 domain family member 4

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025