HitPredict

Interactor 1: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25693804, 25665578
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 1821
+	Hs
		1153882 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		1016285 IF16_HUMAN (1-785): 0: 1155: 100.00		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		1085870 IF16_HUMAN (1-785): 0: 1155: 100.00		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		1085801 IF16_HUMAN (1-785): 0: 1155: 100.00		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1085988 IF16_HUMAN (1-785): 0: 1155: 100.00		NLE1_HUMAN (1-79): 1.4e-13: 77.6: 12.66
+	Hs
		781730 MNDA_HUMAN (486-772): 1.61e-106: 334: 37.67		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		1016290 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		TBL3_HUMAN (7-495): 2.68e-90: 315: 14.31
+	Hs
		197040 IFIX_HUMAN (485-768): 1.32e-102: 326: 39.13		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35