HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29089422, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1821
+	Hs
		918554 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Hs
		420817 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		903263 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		707570 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1087323 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		FBXW7_HUMAN (294-657): 3.51e-56: 211: 17.33
+	Hs
		1087388 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TBL1R_HUMAN (299-580): 2.26e-57: 210: 13.71
+	Hs
		1087228 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		918481 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		707673 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1274424 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		TEP1_HUMAN (4-454): 7.05e-35: 148: 7.87
+	Hs
		883051 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		TEP1_HUMAN (4-454): 7.05e-35: 148: 7.87
+	Hs
		245607 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TBL1X_HUMAN (423-696): 1.86e-26: 118: 13.03
+	Hs
		196995 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PRP4_HUMAN (160-494): 2.06e-16: 86.7: 25.35
+	Sc
		355860 H2B2_YEAST (3-125): 4.73e-37: 124: 71.55		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Sc
		355443 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Hs
		267752 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TAF5L_HUMAN (260-496): 8.94e-09: 62.4: 26.16
+	Sc
		355459 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		TAF5_YEAST (181-311): 6.96e-09: 63.2: 32.58