Protein: PKHA1
Pleckstrin homology domain-containing family A member 1 (PH domain-containing family A member 1) (Tandem PH domain-containing protein 1) (TAPP-1)

Gene: PKHA1, PLEKHA1
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9HB21

Gene Ontology (top 5):
GO:0001553 - luteinization
GO:0005543 - phospholipid binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375966

RASK
GTPase KRas

2

20

High-throughput

0.754

High

978316

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

1437923

ALK
ALK tyrosine kinase receptor

2

20

High-throughput

0.754

High

1437921

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.702

High

855941

CRKL
Crk-like protein

1

20

High-throughput

0.656

High

720328

UFO
Tyrosine-protein kinase receptor UFO

1

20

High-throughput

0.646

High

1090185

PTN13
Tyrosine-protein phosphatase non-receptor type 13

2

12

Small-scale

0.646

High

299794

MPDZ
Multiple PDZ domain protein

2

20

Small-scale

0.643

High

1208379

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

2

7

High-throughput

0.628

High

1437904

PKHA2
Pleckstrin homology domain-containing family A member 2

1

16

Small-scale

0.621

High

126811

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

181826

EPHB6
Ephrin type-B receptor 6

1

20

High-throughput

0.618

High

341146

DIRA3
GTP-binding protein Di-Ras3

1

11

High-throughput

0.618

High

349247

LATS1
Serine/threonine-protein kinase LATS1

1

10

High-throughput

0.618

High

363881

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

374203

RASN
GTPase NRas

1

20

High-throughput

0.618

High

412636

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

439850

INSR
Insulin receptor

1

20

High-throughput

0.618

High

463776

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

465655

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.618

High

466470

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

541695

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

601451

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

630979

RAB4A
Ras-related protein Rab-4A

1

7

High-throughput

0.618

High

631486

RAB5A
Ras-related protein Rab-5A

1

11

High-throughput

0.618

High

648683

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

710895

EPHB2
Ephrin type-B receptor 2

1

20

High-throughput

0.618

High

901584

RAB7A
Ras-related protein Rab-7a

1

15

High-throughput

0.618

High

902082

RAB9A
Ras-related protein Rab-9A

1

19

High-throughput

0.618

High

910206

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

931901

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.618

High

932137

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.618

High

936452

AFAD
Afadin

1

20

High-throughput

0.618

High

953683

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

955616

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

962507

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

962832

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

975256

ARF6
ADP-ribosylation factor 6

1

17

High-throughput

0.618

High

976574

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.618

High

988724

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015802

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1034350

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.618

High

1145118

RAB35
Ras-related protein Rab-35

1

14

High-throughput

0.618

High

1147437

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.618

High

1151884

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1157072

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.618

High

1235334

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.618

High

1271000

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1396632

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1433516

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1433935

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.618

High

1437917

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1437919

LATS2
Serine/threonine-protein kinase LATS2

1

11

High-throughput

0.618

High

294753

PR15A
Protein phosphatase 1 regulatory subunit 15A

2

0

High-throughput

0.602

High

1328607

MS3L1
MSL complex subunit 3

2

0

High-throughput

0.602

High

540685

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.584

High

966891

1433G
14-3-3 protein gamma

1

20

High-throughput

0.554

High

1049803

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

338721

CLD14
Claudin-14

1

0

High-throughput

0.536

High

1437920

SNTG1
Gamma-1-syntrophin

1

19

Small-scale

0.527

High

1293566

F131B
Protein FAM131B

1

0

High-throughput

0.513

High

1415077

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.513

High

1437924

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

1332321

ZN610
Zinc finger protein 610

1

20

High-throughput

0.489

High

1398842

DOCK7
Dedicator of cytokinesis protein 7

1

3

High-throughput

0.489

High

189854

STX7
Syntaxin-7

1

6

High-throughput

0.479

High

218796

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

226211

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

242977

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

299379

FLOT1
Flotillin-1

1

5

High-throughput

0.479

High

556354

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

562407

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.479

High

582966

EZRI
Ezrin

1

20

High-throughput

0.479

High

604216

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

643078

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

691448

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

715786

MARCS
Myristoylated alanine-rich C-kinase substrate

1

7

High-throughput

0.479

High

730257

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

730897

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

951858

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

High-throughput

0.479

High

972015

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.479

High

990756

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1004205

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.479

High

1041303

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1087293

STX4
Syntaxin-4

1

6

High-throughput

0.479

High

1159857

OCLN
Occludin

1

4

High-throughput

0.479

High

1229090

RNF43
E3 ubiquitin-protein ligase RNF43

1

4

High-throughput

0.479

High

1233495

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1322995

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

1353278

PARD3
Partitioning defective 3 homolog

1

19

High-throughput

0.479

High

1381971

CK052
Uncharacterized protein C11orf52

1

6

High-throughput

0.479

High

1399098

SCLT1
Sodium channel and clathrin linker 1

1

14

High-throughput

0.479

High

1400334

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1432973

DNJC5
DnaJ homolog subfamily C member 5

1

9

High-throughput

0.479

High

1437918

E41LA
Band 4.1-like protein 4A

1

15

High-throughput

0.479

High

1437922

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1397113

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

139994

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

276180

NIPS2
Protein NipSnap homolog 2

1

1

Small-scale

0.437

High

327456

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.437

High

1276324

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

1293157

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

823915

PBX2
Pre-B-cell leukemia transcription factor 2

2

0

High-throughput

0.328

High

377727

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025