HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21739721
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HAT_KAT11~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2442
+	Hs
		998782 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		707606 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		1087293 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		918554 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		170321 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		170383 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		TIF1A_HUMAN (667-1202): 2.17e-34: 147: 17.97
+	Hs
		1066994 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631389 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		631445 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		918378 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631358 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		707639 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		1087228 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		918481 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		1017308 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		1017333 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		918323 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09
+	Hs
		1087449 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		918744 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CHD7_HUMAN (70-467): 2.16e-11: 72.1: 9.68
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89