HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 2004
+	Hs
		1129832 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		KAT6A_HUMAN (1-2004): 0: 1040: 100.00
+	Hs
		617965 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT6A_HUMAN (1-2004): 0: 1040: 100.00
+	Hs
		309661 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		309686 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Mm
		1145470 H2B2B_MOUSE (1-126): 2.34e-54: 168: 97.62		KAT5_MOUSE (292-779): 1.57e-131: 424: 34.82
+	Hs
		918578 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Hs
		1018625 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		918325 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		918541 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CHD5_HUMAN (165-468): 3.23e-53: 209: 12.87
+	Hs
		1059777 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		918368 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		918573 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		617961 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		KAT6B_HUMAN (924-2004): 4.93e-40: 166: 37.06
+	Hs
		1264460 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		KAT6B_HUMAN (924-2004): 4.93e-40: 166: 37.06
+	Hs
		1129828 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Hs
		918547 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Hs
		1056919 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19
+	Hs
		918364 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MDC1_HUMAN (807-1825): 3.66e-30: 133: 11.19
+	Hs
		918533 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KMT2C_HUMAN (229-311): 4.1e-22: 107: 37.35
+	Hs
		918628 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		MINT_HUMAN (748-1864): 3.86e-13: 77.8: 10.17