HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: VRK1 (Q99986)
Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1)
Gene: VRK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28927264, 17938195
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 396
+	Hs
		918493 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		VRK2_HUMAN (10-396): 5.7e-124: 369: 47.03
+	Hs
		1307121 H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		918643 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		1231235 H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03		VRK1_HUMAN (1-396): 1.57e-100: 305: 100.00
+	Hs
		1087241 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		VRK3_HUMAN (21-329): 4.13e-62: 208: 36.08
+	Hs
		1217341 H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03		VRK3_HUMAN (21-329): 4.13e-62: 208: 36.08