HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 651
+	Hs
		918709 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		617938 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		876685 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		876694 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BRPF1_HUMAN (4-406): 3.3e-56: 208: 19.24
+	Hs
		319121 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		617986 H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21		BRPF3_HUMAN (3-537): 1.76e-54: 203: 16.33
+	Hs
		319162 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		319214 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		998782 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1087308 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1087293 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PHIP_HUMAN (115-637): 1.3e-38: 155: 12.74
+	Hs
		918554 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHIP_HUMAN (115-637): 1.3e-38: 155: 12.74
+	Hs
		631389 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		631445 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		918674 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD8_HUMAN (2-261): 5.61e-27: 119: 16.23
+	Hs
		918760 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BAZ2A_HUMAN (70-240): 3.27e-19: 94.9: 22.65
+	Hs
		1017308 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Hs
		1017333 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Hs
		1274470 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		BAZ2B_HUMAN (59-225): 1.34e-18: 93: 19.16
+	Hs
		918323 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52