Protein: MRM1
rRNA methyltransferase 1, mitochondrial (EC 2.1.1.-) (21S rRNA (guanosine(2270)-2'-O)-methyltransferase) (21S rRNA [Gm2270] 2'-O-methyltransferase) (Mitochondrial large ribosomal RNA ribose methylase) (Petite colonies protein 56)

Gene: MRM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P25270

Gene Ontology (top 5):
GO:0000154 - rRNA modification
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0008989 - rRNA (guanine-N1-)-methyltransferase activity
GO:0016435 - rRNA (guanine) methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

670184

RM10
Large ribosomal subunit protein uL15m

3

1

High-throughput

0.662

High

626602

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.515

High

603015

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

670188

LSM5
LSM complex subunit LSM5

1

1

High-throughput

0.508

High

670201

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

2

High-throughput

0.489

High

670199

RPM2
Ribonuclease P protein component, mitochondrial

1

0

Small-scale

0.480

High

670176

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

670177

RM09
Large ribosomal subunit protein uL3m

1

4

High-throughput

0.479

High

670181

RML2
Large ribosomal subunit protein uL2m

1

4

High-throughput

0.479

High

670192

MRH4
ATP-dependent RNA helicase MRH4, mitochondrial

1

1

Small-scale

0.479

High

670205

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

670206

RM01
Large ribosomal subunit protein uL1m

1

3

High-throughput

0.479

High

670209

RM23
Large ribosomal subunit protein uL13m

1

3

High-throughput

0.479

High

624717

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

628122

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.458

High

657413

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.458

High

670175

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

670183

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

670185

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.458

High

670186

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.458

High

670187

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.458

High

670194

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.458

High

670196

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.458

High

670204

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

670182

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

380980

H2B1
Histone H2B.1

1

2

High-throughput

0.437

High

381413

H2B2
Histone H2B.2

1

2

High-throughput

0.437

High

392279

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.437

High

670193

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

670197

H3
Histone H3

1

1

High-throughput

0.437

High

670180

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.407

High

670189

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

464557

PBS2
MAP kinase kinase PBS2

1

0

High-throughput

0.279

Low

670178

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.279

Low

670198

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.279

Low

670202

PKH3
Serine/threonine-protein kinase PKH3

1

0

High-throughput

0.279

Low

670203

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.279

Low

670195

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

High-throughput

0.269

Low

670179

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

670190

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

670191

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

670207

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

670208

HBT1
Protein HBT1

1

0

High-throughput

0.249

Low

670200

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025