HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 589
+	Hs
		707791 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Hs
		886213 H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1087430 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Hs
		707764 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Hs
		1136638 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		924319 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		883009 H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		918278 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924315 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924375 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924398 H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924377 H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		918277 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924017 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924103 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		241495 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924129 H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		924107 H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68