HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: PHF8 (Q9UPP1)
Histone lysine demethylase PHF8 (EC 1.14.11.27) (EC 1.14.11.65) (PHD finger protein 8) ([histone H3]-dimethyl-L-lysine(36) demethylase PHF8) ([histone H3]-dimethyl-L-lysine(9) demethylase PHF8)
Gene: PHF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1060
+	Hs
		256396 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		256413 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PHF2_HUMAN (37-1060): 0: 1122: 46.37
+	Hs
		1087500 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		918780 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KDM2A_HUMAN (90-901): 0: 622: 25.09
+	Hs
		918535 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		KDM2B_HUMAN (75-968): 0: 601: 24.09
+	Hs
		1017308 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		1017333 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		918323 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BPTF_HUMAN (30-153): 6.03e-29: 128: 22.40
+	Hs
		918742 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		CXXC1_HUMAN (11-145): 9.34e-28: 122: 25.93
+	Sp
		392632 H2B1_SCHPO (4-125): 1.24e-45: 145: 70.49		MSC1_SCHPO (43-202): 1.49e-28: 126: 18.01
+	Zm
		17621 B4FYZ0_MAIZE (2-125): 7.85e-44: 142: 65.32		A0A1D6GXC6_MAIZE (30-143): 3.34e-22: 106: 21.01
+	Zm
		17631 B6T1G5_MAIZE (14-125): 6.43e-44: 142: 69.64		A0A1D6GXC6_MAIZE (30-143): 3.34e-22: 106: 21.01
+	Sc
		355605 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		SPP1_YEAST (13-147): 3.22e-29: 122: 19.26
+	Hs
		1087376 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		918650 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		241628 H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43
+	Hs
		707733 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		DIDO1_HUMAN (41-92): 9.31e-11: 68.6: 46.43