HitPredict

Interactor 1: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Interactor 2: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 27432908, 15978577
Identification Methods affinity chromatography technology, comigration in sds page, tox-r dimerization assay
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0000902 - cell morphogenesis
GO:0002548 - monocyte chemotaxis
GO:0003093 - regulation of glomerular filtration
GO:0003105 - negative regulation of glomerular filtration
GO:0004725 - protein tyrosine phosphatase activity
and 30 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

1 1216
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Last updated: 15 Jul 2024