HitPredict

Interactor 1: H0YKT8 (H0YKT8)
Proteasome subunit beta
Gene: PSMA4

Interactor 2: PSMD7 (P51665)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Mov34 protein homolog) (Proteasome subunit p40)
Gene: PSMD7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 324
+	Dm
		640767 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSMD7_DROME (3-323): 3.82e-118: 345: 75.54
+	Hs
		637651 PSA2_HUMAN (1-178): 1.38e-77: 233: 38.76		PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00
+	Mm
		643130 PSA1_MOUSE (1-177): 4.11e-76: 229: 29.21		PSMD7_MOUSE (1-285): 4.25e-110: 324: 99.30
+	Dm
		640776 PSA5_DROME (1-179): 2.3e-67: 207: 27.96		PSMD7_DROME (3-323): 3.82e-118: 345: 75.54
+	Dm
		574013 PSA4_DROME (1-181): 9.01e-66: 203: 73.37		PSMD7_DROME (3-323): 3.82e-118: 345: 75.54
+	Dm
		611629 PSA71_DROME (2-181): 2.94e-64: 199: 28.18		PSMD7_DROME (3-323): 3.82e-118: 345: 75.54
+	Hs
		638089 PSA4_HUMAN (1-181): 1.2e-69: 213: 100.00		PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00
+	Hs
		656177 PSA5_HUMAN (1-179): 2.12e-66: 204: 31.52		PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00
+	Hs
		849173 PSA6_HUMAN (2-180): 6.87e-65: 201: 28.73		PSMD7_HUMAN (1-285): 5.24e-110: 324: 100.00
+	Sc
		771389 PSA4_YEAST (1-178): 5.6e-67: 206: 32.60		RPN8_YEAST (7-322): 1.4e-99: 298: 47.01
+	Sc
		619393 PSA3_YEAST (1-179): 1.05e-65: 203: 53.63		RPN8_YEAST (7-322): 1.4e-99: 298: 47.01
+	Sc
		619520 PSA2_YEAST (1-178): 1.91e-29: 110: 37.99		RPN8_YEAST (7-322): 1.4e-99: 298: 47.01
+	Sp
		784767 PSA3_SCHPO (1-180): 2.19e-67: 207: 52.22		RPN11_SCHPO (7-217): 2.01e-50: 171: 19.26
+	Sp
		784781 PSA5_SCHPO (1-179): 1.89e-64: 199: 32.97		RPN11_SCHPO (7-217): 2.01e-50: 171: 19.26
+	Hs
		156334 PSA7_HUMAN (2-179): 8.31e-68: 208: 32.96		CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38
+	Hs
		893720 PSA6_HUMAN (2-180): 6.87e-65: 201: 28.73		CSN5_HUMAN (7-160): 1.07e-41: 149: 19.38
+	Dm
		771306 PSA2_DROME (1-178): 4.03e-76: 229: 37.08		PSDE_DROME (5-142): 5.79e-28: 112: 24.31
+	Dm
		1278634 PSA5_DROME (1-179): 2.3e-67: 207: 27.96		PSDE_DROME (5-142): 5.79e-28: 112: 24.31
+	Dm
		574029 PSA4_DROME (1-181): 9.01e-66: 203: 73.37		PSDE_DROME (5-142): 5.79e-28: 112: 24.31
+	Dm
		611650 PSA71_DROME (2-181): 2.94e-64: 199: 28.18		PSDE_DROME (5-142): 5.79e-28: 112: 24.31