HitPredict

Interactor 1: NPR1 (Q18534)
Neuropeptide receptor npr-1 (Neuropeptide Y receptor homolog npr-1)
Gene: npr-1

Interactor 2: FLP18 (Q9N4V0)
FMRFamide-like neuropeptide 18 [Cleaved into: EMPGVLRF-amide; SVPGVLRF-amide 1; SVPGVLRF-amide 2; EIPGVLRF-amide; SEVPGVLRF-amide; DVPGVLRF-amide; SVPGVLRF-amide 3]
Gene: flp-18

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	14555955, 16768454, 31533726
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006937 - regulation of muscle contraction GO:0007218 - neuropeptide signaling pathway GO:0030431 - sleep
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 457 Ce			1 208
+	Ce
		1093710 Q20275_CAEEL (14-392): 9.47e-74: 239: 27.46		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		1150975 Q6F3C9_CAEEL (29-345): 1.53e-49: 176: 31.48		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		247924 O62062_CAEEL (5-354): 1.72e-42: 158: 30.62		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		1095285 Q23305_CAEEL (29-351): 2.18e-38: 146: 29.91		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		1150826 Q6EUU1_CAEEL (8-350): 5.15e-38: 143: 28.70		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		1089848 NPR11_CAEEL (29-350): 2.05e-31: 126: 28.18		FLP18_CAEEL (1-208): 1.1e-129: 365: 100.00
+	Ce
		1093706 Q20275_CAEEL (14-392): 9.47e-74: 239: 27.46		FLP03_CAEEL (53-149): 2.18e-12: 64.7: 35.71
+	Ce
		1095258 Q6F3C9_CAEEL (29-345): 1.53e-49: 176: 31.48		FLP03_CAEEL (53-149): 2.18e-12: 64.7: 35.71
+	Ce
		247923 O62062_CAEEL (5-354): 1.72e-42: 158: 30.62		FLP03_CAEEL (53-149): 2.18e-12: 64.7: 35.71
+	Ce
		1095257 Q6EUU1_CAEEL (8-350): 5.15e-38: 143: 28.70		FLP03_CAEEL (53-149): 2.18e-12: 64.7: 35.71