Protein: E41L1
Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N)

Gene: E41L1, EPB41L1
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q9H4G0

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

217522

E41L2
Band 4.1-like protein 2

2

16

High-throughput

0.811

High

1433658

E41L3
Band 4.1-like protein 3

2

15

High-throughput

0.811

High

1404714

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

2

8

Small-scale

0.808

High

374928

RASH
GTPase HRas

2

20

High-throughput

0.754

High

375951

RASK
GTPase KRas

2

20

High-throughput

0.754

High

978302

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

539010

EPB41
Protein 4.1

1

15

High-throughput

0.691

High

720325

UFO
Tyrosine-protein kinase receptor UFO

1

20

High-throughput

0.646

High

350307

DDAH2
Putative hydrolase DDAH2

4

4

High-throughput

0.630

High

134454

EF2K
Eukaryotic elongation factor 2 kinase

2

3

High-throughput

0.628

High

230662

PRIC3
Prickle planar cell polarity protein 3

2

15

High-throughput

0.628

High

926224

ICLN
Methylosome subunit pICln

2

6

High-throughput

0.628

High

1309167

MISP
Mitotic interactor and substrate of PLK1

2

4

High-throughput

0.628

High

126801

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

341142

DIRA3
GTP-binding protein Di-Ras3

1

12

High-throughput

0.618

High

363857

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

374195

RASN
GTPase NRas

1

20

High-throughput

0.618

High

440209

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.618

High

463768

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

466459

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

581289

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

582960

EZRI
Ezrin

1

16

High-throughput

0.618

High

601444

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

614733

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

7

High-throughput

0.618

High

710493

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

910197

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

953672

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

955593

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

956491

RAB2A
Ras-related protein Rab-2A

1

8

High-throughput

0.618

High

962481

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

976560

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.618

High

988705

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1015784

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1145110

RAB35
Ras-related protein Rab-35

1

12

High-throughput

0.618

High

1151875

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1270994

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1366883

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1433504

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1433635

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1433637

E41LA
Band 4.1-like protein 4A

1

15

High-throughput

0.618

High

1433653

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.618

High

691429

1433T
14-3-3 protein theta

2

20

High-throughput

0.611

High

966871

1433G
14-3-3 protein gamma

2

20

High-throughput

0.611

High

1102906

EIF3I
Eukaryotic translation initiation factor 3 subunit I

2

3

High-throughput

0.611

High

1433642

KTU
Protein kintoun

2

3

High-throughput

0.611

High

190168

TNC18
Trinucleotide repeat-containing gene 18 protein

2

5

High-throughput

0.601

High

730240

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

1145366

RNPS1
RNA-binding protein with serine-rich domain 1

2

11

High-throughput

0.601

High

1346641

VANG1
Vang-like protein 1

2

10

High-throughput

0.601

High

1432351

PININ
Pinin

2

5

High-throughput

0.601

High

1433636

CWC22
Pre-mRNA-splicing factor CWC22 homolog

2

7

High-throughput

0.601

High

1433645

CXXC1
CXXC-type zinc finger protein 1

2

3

High-throughput

0.601

High

1433651

ACINU
Apoptotic chromatin condensation inducer in the nucleus

2

19

High-throughput

0.601

High

1433652

VANG2
Vang-like protein 2

2

10

High-throughput

0.601

High

838464

GRIA1
Glutamate receptor 1

2

12

Small-scale

0.595

High

1164236

DGUOK
Deoxyguanosine kinase, mitochondrial

2

0

High-throughput

0.585

High

1433643

ARMC1
Armadillo repeat-containing protein 1

2

0

High-throughput

0.585

High

771647

DRD3
D(3) dopamine receptor

1

2

Small-scale

0.573

High

1134723

NUMA1
Nuclear mitotic apparatus protein 1

1

14

Small-scale

0.573

High

396937

ESR1
Estrogen receptor

2

19

High-throughput

0.571

High

870109

GRIA4
Glutamate receptor 4

1

12

Small-scale

0.561

High

1006709

SRPK2
SRSF protein kinase 2

1

15

High-throughput

0.550

High

126184

AP3B1
AP-3 complex subunit beta-1

2

5

High-throughput

0.549

High

175927

SET1A
Histone-lysine N-methyltransferase SETD1A

2

10

High-throughput

0.549

High

1290723

ZCH18
Zinc finger CCCH domain-containing protein 18

2

15

High-throughput

0.549

High

1348958

ZCH10
Zinc finger CCHC domain-containing protein 10

2

8

High-throughput

0.549

High

1393408

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

3

High-throughput

0.549

High

1433646

AFF4
AF4/FMR2 family member 4

2

16

High-throughput

0.549

High

1433650

GPTC8
G patch domain-containing protein 8

2

14

High-throughput

0.549

High

1433657

SRRM2
Serine/arginine repetitive matrix protein 2

2

19

High-throughput

0.549

High

415862

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.541

High

477177

ACM5
Muscarinic acetylcholine receptor M5

1

3

High-throughput

0.541

High

134868

SAP18
Histone deacetylase complex subunit SAP18

1

3

High-throughput

0.536

High

269810

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

4

High-throughput

0.536

High

530378

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.536

High

718462

CD6
T-cell differentiation antigen CD6

1

7

High-throughput

0.536

High

839920

AF9
Protein AF-9

1

13

High-throughput

0.536

High

971997

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

974842

SMD3
Small nuclear ribonucleoprotein Sm D3

1

4

High-throughput

0.536

High

990729

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1040756

ENL
Protein ENL

1

14

High-throughput

0.536

High

1280223

MILR1
Allergin-1

1

4

High-throughput

0.536

High

1323283

KT222
Keratin-like protein KRT222

1

7

High-throughput

0.536

High

1357753

TRI41
E3 ubiquitin-protein ligase TRIM41

1

5

High-throughput

0.536

High

1410369

MEP50
Methylosome protein WDR77

1

4

High-throughput

0.536

High

106651

APRIO
Alternative prion protein

2

7

High-throughput

0.533

High

1129035

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

0

Small-scale

0.529

High

572473

DRD2
D(2) dopamine receptor

1

4

Small-scale

0.527

High

928550

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.523

High

1433655

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

8

High-throughput

0.514

High

906930

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

1389115

KBP
KIF-binding protein

1

0

High-throughput

0.513

High

1433634

CB39L
Calcium-binding protein 39-like

1

0

High-throughput

0.513

High

1433660

STA13
StAR-related lipid transfer protein 13

1

8

Small-scale

0.508

High

423162

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

674329

BRD2
Bromodomain-containing protein 2

1

8

High-throughput

0.489

High

889661

CLK2
Dual specificity protein kinase CLK2

1

7

High-throughput

0.489

High

889812

CLK3
Dual specificity protein kinase CLK3

1

7

High-throughput

0.489

High

908292

AFF1
AF4/FMR2 family member 1

1

16

High-throughput

0.489

High

1249395

CWC27
Spliceosome-associated protein CWC27 homolog

1

2

High-throughput

0.489

High

1413980

MMTA2
Multiple myeloma tumor-associated protein 2

1

3

High-throughput

0.489

High

1433638

ANKE1
Ankyrin repeat and EF-hand domain-containing protein 1

1

11

High-throughput

0.489

High

1433654

SCML1
Sex comb on midleg-like protein 1

1

4

High-throughput

0.489

High

1433659

AP3M1
AP-3 complex subunit mu-1

1

5

High-throughput

0.489

High

1433661

MYH4
Myosin-4

1

4

High-throughput

0.489

High

404418

GCR
Glucocorticoid receptor

1

18

Small-scale

0.481

High

1433641

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

7

Small-scale

0.481

High

189843

STX7
Syntaxin-7

1

8

High-throughput

0.479

High

299373

FLOT1
Flotillin-1

1

9

High-throughput

0.479

High

540675

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.479

High

556344

CADH1
Cadherin-1

1

15

High-throughput

0.479

High

604206

CXA1
Gap junction alpha-1 protein

1

8

High-throughput

0.479

High

643069

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

10

High-throughput

0.479

High

715776

MARCS
Myristoylated alanine-rich C-kinase substrate

1

11

High-throughput

0.479

High

760502

SDC2
Syndecan-2

1

6

Small-scale

0.479

High

791730

SYUA
Alpha-synuclein

1

6

High-throughput

0.479

High

845804

MUC18
Cell surface glycoprotein MUC18

1

15

High-throughput

0.479

High

975243

ARF6
ADP-ribosylation factor 6

1

6

High-throughput

0.479

High

1004200

CXAR
Coxsackievirus and adenovirus receptor

1

7

High-throughput

0.479

High

1041289

CAV1
Caveolin-1

1

7

High-throughput

0.479

High

1049782

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1159845

OCLN
Occludin

1

10

High-throughput

0.479

High

1255530

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

1432967

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.479

High

1056971

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.457

High

183515

CASC3
Protein CASC3

1

6

High-throughput

0.445

High

193819

PER1
Period circadian protein homolog 1

1

5

High-throughput

0.445

High

404914

PRIO
Major prion protein

1

4

High-throughput

0.445

High

786849

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

Small-scale

0.445

High

967968

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

Small-scale

0.445

High

968445

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

8

Small-scale

0.445

High

1186504

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

8

High-throughput

0.445

High

1234955

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

1239666

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

2

High-throughput

0.445

High

1250522

RBP10
Ran-binding protein 10

1

5

High-throughput

0.445

High

1252386

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.445

High

1257944

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

7

High-throughput

0.445

High

1324793

LAT4
Large neutral amino acids transporter small subunit 4

1

5

High-throughput

0.445

High

1353452

PNISR
Arginine/serine-rich protein PNISR

1

3

High-throughput

0.445

High

1433644

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

3

High-throughput

0.445

High

1395028

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

327448

ZFPL1
Zinc finger protein-like 1

1

6

High-throughput

0.437

High

1293150

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1381966

CK052
Uncharacterized protein C11orf52

1

8

High-throughput

0.437

High

1433648

XPO7
Exportin-7

1

2

High-throughput

0.437

High

1142816

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.426

High

1244532

SHQ1
Protein SHQ1 homolog

1

0

High-throughput

0.426

High

158883

AP3D1
AP-3 complex subunit delta-1

1

7

High-throughput

0.407

High

160133

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

7

High-throughput

0.407

High

326780

DUS14
Dual specificity protein phosphatase 14

1

1

High-throughput

0.407

High

1217017

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

7

High-throughput

0.407

High

1218541

PPRC1
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

1

7

High-throughput

0.407

High

1258579

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

3

High-throughput

0.407

High

1277090

PRIC2
Prickle-like protein 2

1

14

High-throughput

0.407

High

1364931

AP3S1
AP-3 complex subunit sigma-1

1

8

High-throughput

0.407

High

1394888

EAF1
ELL-associated factor 1

1

2

High-throughput

0.407

High

1404325

NP1L3
Nucleosome assembly protein 1-like 3

1

5

High-throughput

0.407

High

1433649

BAZ2B
Bromodomain adjacent to zinc finger domain protein 2B

1

13

High-throughput

0.407

High

1433656

SET1B
Histone-lysine N-methyltransferase SETD1B

1

10

High-throughput

0.407

High

1433647

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

124493

HAX1
HCLS1-associated protein X-1

2

0

High-throughput

0.318

High

1433639

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High

665713

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.279

Low

1288252

LYRIC
Protein LYRIC

1

0

High-throughput

0.279

Low

1383907

ISG20
Interferon-stimulated gene 20 kDa protein

1

0

High-throughput

0.279

Low

1433640

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.279

Low

880691

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

298863

LYZL6
Lysozyme-like protein 6

1

0

High-throughput

0.232

Low

598772

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025