HitPredict

Interactor 1: SMCL1 (Q18616)
Structural maintenance of chromosomes-like protein 1
Gene: smcl-1

Interactor 2: SMC4 (Q20060)
Structural maintenance of chromosomes protein 4 (SMC protein 4) (SMC-4)
Gene: smc-4

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28301465
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SMC_N~SMC_N
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 537 Ce			1 1549
+	Sc
		810789 SMC4_YEAST (150-535): 9.91e-45: 171: 14.95		SMC3_YEAST (90-1369): 2.2e-158: 515: 18.49
+	Sc
		700779 SMC1_YEAST (6-426): 4.62e-44: 169: 17.92		SMC3_YEAST (90-1369): 2.2e-158: 515: 18.49
+	Ce
		823189 SMCL1_CAEEL (1-537): 1.02e-90: 289: 100.00		DPY27_CAEEL (55-1366): 1.11e-100: 357: 28.06
+	Ce
		999499 SMCL1_CAEEL (1-537): 1.02e-90: 289: 100.00		MIX1_CAEEL (90-1365): 8.31e-78: 285: 15.21
+	Hs
		311633 SMC2_HUMAN (6-463): 9.91e-46: 174: 11.66		SMC4_HUMAN (11-1370): 4.52e-105: 367: 28.19
+	Mm
		1265312 SMC1B_MOUSE (6-461): 6.5e-47: 178: 17.13		SMC1A_MOUSE (90-1371): 2.62e-82: 299: 18.01
+	Hs
		1057252 SMC1A_HUMAN (105-535): 3.29e-45: 173: 18.28		SMC1A_HUMAN (90-1371): 2.79e-82: 299: 17.94
+	Sc
		700811 SMC4_YEAST (150-535): 9.91e-45: 171: 14.95		SMC1_YEAST (90-1371): 8.04e-63: 238: 19.07
+	Sc
		700754 SMC1_YEAST (6-426): 4.62e-44: 169: 17.92		SMC1_YEAST (90-1371): 8.04e-63: 238: 19.07
+	Xl
		840134 SMC4_XENLA (4-455): 1.96e-48: 182: 13.29		SMC2_XENLA (330-1368): 7.64e-52: 202: 14.52
+	Sp
		780419 SMC4_SCHPO (92-535): 9.51e-50: 186: 14.83		SMC2_SCHPO (335-1361): 1.97e-48: 191: 14.37
+	Bs
		850842 SMC_BACSU (6-396): 5.86e-45: 172: 14.22		SMC_BACSU (344-1374): 2.86e-47: 188: 14.16
+	Sc
		758766 SMC4_YEAST (150-535): 9.91e-45: 171: 14.95		SMC2_YEAST (339-1361): 2.39e-44: 178: 15.02
+	Sc
		700765 SMC1_YEAST (6-426): 4.62e-44: 169: 17.92		SMC2_YEAST (339-1361): 2.39e-44: 178: 15.02
+	Mm
		1265313 SMC1B_MOUSE (6-461): 6.5e-47: 178: 17.13		SMC3_MOUSE (366-1378): 1.41e-40: 166: 12.70
+	Hs
		311648 SMC2_HUMAN (6-463): 9.91e-46: 174: 11.66		SMC3_HUMAN (366-1378): 1.64e-40: 166: 12.70
+	Hs
		1057429 SMC1A_HUMAN (105-535): 3.29e-45: 173: 18.28		SMC3_HUMAN (366-1378): 1.64e-40: 166: 12.70
+	Mm
		1321813 SMC1A_MOUSE (105-535): 3.03e-45: 173: 18.50		SMC3_MOUSE (366-1378): 1.41e-40: 166: 12.70
+	Bt
		333283 SMC1A_BOVIN (105-535): 3.11e-45: 173: 18.28		SMC3_BOVIN (366-1378): 5.77e-40: 164: 12.50