Protein: RFWD3
E3 ubiquitin-protein ligase RFWD3 (EC 2.3.2.27) (RING finger and WD repeat domain-containing protein 3) (RING finger protein 201)

Gene: RFWD3
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q6PCD5

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849343

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

High-throughput

0.815

High

895816

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

High-throughput

0.815

High

919753

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

High-throughput

0.815

High

1160856

UB2D4
Ubiquitin-conjugating enzyme E2 D4

2

20

High-throughput

0.815

High

651483

RFA1
Replication protein A 70 kDa DNA-binding subunit

10

2

Small-scale

0.754

High

552981

RFA2
Replication protein A 32 kDa subunit

9

0

Small-scale

0.723

High

851824

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

896465

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.698

High

1160836

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

High-throughput

0.698

High

1160837

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

720730

RFA3
Replication protein A 14 kDa subunit

6

0

Small-scale

0.697

High

1160842

TCPH
T-complex protein 1 subunit eta

3

6

High-throughput

0.675

High

636493

DNJB2
DnaJ homolog subfamily B member 2

3

2

High-throughput

0.667

High

1160830

RFWD3
E3 ubiquitin-protein ligase RFWD3

1

17

Small-scale

0.665

High

475927

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

15

High-throughput

0.647

High

1160850

MBIP1
MAP3K12-binding inhibitory protein 1

3

0

High-throughput

0.638

High

817689

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

1

High-throughput

0.628

High

227802

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.618

High

1160832

BBS7
Bardet-Biedl syndrome 7 protein

2

0

High-throughput

0.602

High

962826

MDM2
E3 ubiquitin-protein ligase Mdm2

1

3

Small-scale

0.597

High

386941

P53
Cellular tumor antigen p53

1

5

Small-scale

0.586

High

988088

RAD51
DNA repair protein RAD51 homolog 1

1

1

Small-scale

0.586

High

821272

TCPE
T-complex protein 1 subunit epsilon

2

6

High-throughput

0.574

High

943298

TCPB
T-complex protein 1 subunit beta

2

7

High-throughput

0.574

High

1160841

KCC1G
Calcium/calmodulin-dependent protein kinase type 1G

2

3

High-throughput

0.574

High

1033390

ORC1
Origin recognition complex subunit 1

1

1

Small-scale

0.561

High

1033422

ORC2
Origin recognition complex subunit 2

1

1

Small-scale

0.561

High

1131738

CE170
Centrosomal protein of 170 kDa

2

7

High-throughput

0.558

High

529281

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.541

High

517317

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.537

High

243464

DNJA2
DnaJ homolog subfamily A member 2

1

1

High-throughput

0.536

High

499846

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.536

High

538277

ENPL
Endoplasmin

1

6

High-throughput

0.536

High

770896

TCPZ
T-complex protein 1 subunit zeta

1

5

High-throughput

0.536

High

842919

TCPQ
T-complex protein 1 subunit theta

1

7

High-throughput

0.536

High

843252

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.536

High

1160831

TRI74
Tripartite motif-containing protein 74

1

18

High-throughput

0.536

High

1160834

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

1

High-throughput

0.536

High

1160845

RNF41
E3 ubiquitin-protein ligase NRDP1

1

20

High-throughput

0.536

High

1160851

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

1034592

GOGA4
Golgin subfamily A member 4

1

8

High-throughput

0.515

High

1160847

UBP29
Ubiquitin carboxyl-terminal hydrolase 29

1

16

High-throughput

0.515

High

1160840

PRIPO
DNA-directed primase/polymerase protein

1

0

Small-scale

0.513

High

1160853

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

394967

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

281001

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.489

High

573319

TCPA
T-complex protein 1 subunit alpha

1

5

High-throughput

0.489

High

654442

CALX
Calnexin

1

5

High-throughput

0.489

High

826722

TCPG
T-complex protein 1 subunit gamma

1

6

High-throughput

0.489

High

1160835

GSLG1
Golgi apparatus protein 1

1

2

High-throughput

0.489

High

1160849

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.489

High

1160857

HYOU1
Hypoxia up-regulated protein 1

1

6

High-throughput

0.489

High

162884

XPO1
Exportin-1

1

13

High-throughput

0.479

High

245994

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.479

High

431966

HS90A
Heat shock protein HSP 90-alpha

1

7

High-throughput

0.479

High

438276

HS90B
Heat shock protein HSP 90-beta

1

8

High-throughput

0.479

High

798932

GATA4
Transcription factor GATA-4

1

11

High-throughput

0.479

High

917458

H4
Histone H4

1

4

High-throughput

0.479

High

931686

CSK2B
Casein kinase II subunit beta

1

4

High-throughput

0.479

High

1123623

DCAF6
DDB1- and CUL4-associated factor 6

1

11

High-throughput

0.479

High

1160833

RPTOR
Regulatory-associated protein of mTOR

1

14

High-throughput

0.479

High

1160838

RNF31
E3 ubiquitin-protein ligase RNF31

1

6

High-throughput

0.479

High

1160846

ECT2
Protein ECT2

1

2

High-throughput

0.479

High

1160848

MBNL1
Muscleblind-like protein 1

1

3

High-throughput

0.479

High

1160852

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

1

Small-scale

0.479

High

1160854

PRP19
Pre-mRNA-processing factor 19

1

9

Small-scale

0.479

High

87511

C9JP00
Muscleblind like splicing regulator 1

1

3

High-throughput

0.445

High

91324

E5RGS4
Prefoldin subunit 1

1

1

High-throughput

0.445

High

1160843

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

1160839

C170L
Cep170-like protein

1

2

High-throughput

0.407

High

570816

TPH1
Tryptophan 5-hydroxylase 1

2

0

High-throughput

0.328

High

899972

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.279

Low

1160855

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.279

Low

1160844

COA1
Cytochrome c oxidase assembly factor 1 homolog

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024