HitPredict

Interactor 1: WAGO1 (Q21770)
Argonaute protein wago-1 (Worm-specific argonaute protein 1)
Gene: wago-1

Interactor 2: LIN41 (Q9U489)
Protein lin-41 (Abnormal cell lineage protein 41)
Gene: lin-41

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28576864
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0035198 - miRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 945 Ce			1 1147
+	Ce
		108593 G5EGR6_CAEEL (3-931): 0: 835: 19.76		LIN41_CAEEL (1-1147): 0: 1087: 100.00
+	Hs
		1102507 AGO2_HUMAN (59-919): 0: 842: 21.15		LIN41_HUMAN (349-1147): 1.44e-127: 413: 32.30
+	Mm
		1093411 AGO2_MOUSE (46-919): 0: 841: 20.96		LIN41_MOUSE (365-1147): 3.79e-125: 406: 31.94
+	Hs
		585070 AGO3_HUMAN (55-913): 0: 844: 22.51		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		585074 AGO4_HUMAN (51-913): 0: 823: 20.80		RO52_HUMAN (357-848): 1.73e-81: 276: 11.51
+	Hs
		1282069 AGO2_HUMAN (59-919): 0: 842: 21.15		TRI63_HUMAN (361-673): 7.46e-59: 208: 15.18
+	Hs
		1317538 AGO2_HUMAN (59-919): 0: 842: 21.15		TRI55_HUMAN (366-673): 6.7e-49: 185: 12.99
+	Mm
		1208468 AGO1_MOUSE (56-913): 0: 847: 21.97		TRI32_MOUSE (878-1147): 2.31e-29: 127: 23.26
+	Dm
		1103832 Q32KD4_DROME (2-913): 0: 816: 20.39		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Dm
		1100038 Q27IR0_DROME (40-901): 0: 808: 21.02		WECH_DROME (927-1147): 3.56e-36: 150: 27.78
+	Dm
		1103862 Q32KD4_DROME (2-913): 0: 816: 20.39		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Hs
		170510 AGO1_HUMAN (56-913): 0: 847: 21.97		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Hs
		170478 AGO3_HUMAN (55-913): 0: 844: 22.51		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Hs
		170508 AGO2_HUMAN (59-919): 0: 842: 21.15		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1100039 Q27IR0_DROME (40-901): 0: 808: 21.02		Q9W378_DROME (971-1147): 5.1e-26: 118: 22.10
+	Hs
		1294945 PIWL1_HUMAN (3-924): 0: 712: 17.14		TRI54_HUMAN (366-704): 2.45e-58: 207: 13.54
+	Hs
		170484 AGO4_HUMAN (51-913): 0: 823: 20.80		TIF1A_HUMAN (347-664): 5.67e-16: 85.3: 17.79
+	Dm
		1103819 Q32KD4_DROME (2-913): 0: 816: 20.39		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Dm
		1100037 Q27IR0_DROME (40-901): 0: 808: 21.02		BRAT_DROME (368-709): 6.28e-17: 88.5: 13.35
+	Ce
		998324 YQ53_CAEEL (338-905): 8.98e-156: 487: 22.71		Q19818_CAEEL (944-1147): 5.98e-09: 62.6: 24.30